0000000000471902

AUTHOR

P. Severgnini

showing 16 related works from this author

Additional file 2: of Protective intraoperative ventilation with higher versus lower levels of positive end-expiratory pressure in obese patients (PR…

2017

Standard Protocol Items: Recommendations for Interventional Trials (SPIRIT) 2013 checklist: recommended items to address in a clinical trial protocol and related documents. (PDF 122 kb).

behavioral disciplines and activities3. Good health
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Additional file 1: of Protective intraoperative ventilation with higher versus lower levels of positive end-expiratory pressure in obese patients (PR…

2017

PROBESE Study protocol version 2.5. This PDF file includes the most recent version of the PROBESE Study protocol with changes highlighted. (PDF 870Â kb)

ComputingMethodologies_DOCUMENTANDTEXTPROCESSING3. Good health
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The stellar content of the XMM-Newton Bright Serendipitous Survey

2006

Context: The comparison of observed counts in a given sky direction with predictions by Galactic models yields constraints to the spatial distribution and the stellar birthrate of young stellar populations. In this work we present the results of the analysis of the stellar content of the XMM-Newton Bright Serendipitous Survey (XBSS). This unbiased survey includes a total of 58 stellar sources selected in the 0.5 -- 4.5 keV energy band, having a limiting sensitivity of $10^{-2}$ cnt s$^{-1}$ and covering an area of 28.10 sq. deg. Aims: Our main goal is to understand the recent star formation history of the Galaxy in the vicinity of the Sun. Methods: We compare the observations with the predi…

Physicseducation.field_of_studyStar formationmedia_common.quotation_subjectPopulationAstrophysics (astro-ph)FOS: Physical sciencesAstronomy and AstrophysicsContext (language use)AstrophysicsAstrophysics::Cosmology and Extragalactic AstrophysicsAstrophysicsGalaxyStarsSpace and Planetary ScienceSkyMagnitude (astronomy)Content (measure theory)Astrophysics::Solar and Stellar AstrophysicsAstrophysics::Earth and Planetary AstrophysicseducationAstrophysics::Galaxy Astrophysicsmedia_common
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Additional file 1: of Protective ventilation with high versus low positive end-expiratory pressure during one-lung ventilation for thoracic surgery (…

2019

PROTHOR-Patient information. (DOCX 19 kb)

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Additional file 4: of Protective intraoperative ventilation with higher versus lower levels of positive end-expiratory pressure in obese patients (PR…

2017

Standard operating procedures (SOP) for plasma Sampling. (PDF 115Â kb)

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Additional file 1: of Protective intraoperative ventilation with higher versus lower levels of positive end-expiratory pressure in obese patients (PR…

2017

PROBESE Study protocol version 2.5. This PDF file includes the most recent version of the PROBESE Study protocol with changes highlighted. (PDF 870Â kb)

ComputingMethodologies_DOCUMENTANDTEXTPROCESSING3. Good health
researchProduct

Additional file 3: of Protective intraoperative ventilation with higher versus lower levels of positive end-expiratory pressure in obese patients (PR…

2017

PROBESE case report form version 1.2.2. This file corresponds to the paper version of the case report form. (DOC 1610 kb).

3. Good health
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Additional file 2: of Protective intraoperative ventilation with higher versus lower levels of positive end-expiratory pressure in obese patients (PR…

2017

Standard Protocol Items: Recommendations for Interventional Trials (SPIRIT) 2013 checklist: recommended items to address in a clinical trial protocol and related documents. (PDF 122 kb).

behavioral disciplines and activities3. Good health
researchProduct

Additional file 5: of Protective intraoperative ventilation with higher versus lower levels of positive end-expiratory pressure in obese patients (PR…

2017

Standard operating procedures (SOP) for plasma Sampling. (PDF 110Â kb)

researchProduct

Additional file 3: of Protective intraoperative ventilation with higher versus lower levels of positive end-expiratory pressure in obese patients (PR…

2017

PROBESE case report form version 1.2.2. This file corresponds to the paper version of the case report form. (DOC 1610 kb).

3. Good health
researchProduct

Erratum: Protective intraoperative ventilation with higher versus lower levels of positive end-expiratory pressure in obese patients (PROBESE): Study…

2017

Medicine (miscellaneous)Medicine (miscellaneous); Pharmacology (medical)Pharmacology (medical)Protective ventilation
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The NHXM observatory

2011

Exploration of the X-ray sky has established X-ray astronomy as a fundamental astrophysical discipline. While our knowledge of the sky below 10 keV has increased dramatically (∼8 orders of magnitude) by use of grazing incidence optics, we still await a similar improvement above 10 keV, where to date only collimated instruments have been used. Also ripe for exploration is the field of X-ray polarimetry, an unused fundamental tool to understand the physics and morphology of X-ray sources. Here we present a novel mission, the New Hard X-ray Mission (NHXM) that brings together for the first time simultaneous high-sensitivity, hard-X-ray imaging, broadband spectroscopy and polarimetry. NHXM will…

Black-holesAcceleration mechanismCosmic Visionmedia_common.quotation_subjectPolarimetry7. Clean energy01 natural sciencesMissionsCosmologyPhysical cosmologyNon-thermal emissionAcceleration mechanism; Accretion physics; Black-holes; Compact objects; Cosmology; Missions; Non-thermal emission; X-ray imaging; X-ray polarimetry; Astronomy and Astrophysics; Space and Planetary ScienceObservatory0103 physical sciencesBroadbandX-ray polarimetry010303 astronomy & astrophysicsCompact objectsmedia_commonPhysics010308 nuclear & particles physicsX-ray imagingVegaAstronomyAstronomy and AstrophysicsAccretion physicsCosmologySkySpace and Planetary ScienceExperimental Astronomy
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XIPE: the x-ray imaging polarimetry explorer

2016

XIPE, the X-ray Imaging Polarimetry Explorer, is a mission dedicated to X-ray Astronomy. At the time of writing XIPE is in a competitive phase A as fourth medium size mission of ESA (M4). It promises to reopen the polarimetry window in high energy Astrophysics after more than 4 decades thanks to a detector that efficiently exploits the photoelectric effect and to X-ray optics with large effective area. XIPE uniqueness is time-spectrally-spatially- resolved X-ray polarimetry as a breakthrough in high energy astrophysics and fundamental physics. Indeed the payload consists of three Gas Pixel Detectors at the focus of three X-ray optics with a total effective area larger than one XMM mirror bu…

X-ray AstronomyHigh-energy astronomyPolarimetryX-ray opticsX-ray telescopeCondensed Matter Physic01 natural sciencesObservatory0103 physical sciencesPolarimetryElectronicOptical and Magnetic MaterialsSpectral resolutionElectrical and Electronic Engineering010303 astronomy & astrophysicsGas Pixel DetectorPhysicsX-ray astronomyta115X-ray optics010308 nuclear & particles physicsElectronic Optical and Magnetic MaterialApplied MathematicsVegaAstronomyComputer Science Applications1707 Computer Vision and Pattern RecognitionGas Pixel Detector; Polarimetry; X-ray Astronomy; X-ray opticsCondensed Matter PhysicsComputer Science ApplicationsApplied MathematicGas Pixel Detector; Polarimetry; X-ray Astronomy; X-ray optics; Electronic Optical and Magnetic Materials; Condensed Matter Physics; Computer Science Applications1707 Computer Vision and Pattern Recognition; Applied Mathematics; Electrical and Electronic EngineeringGas Pixel Detector; Polarimetry; X-ray Astronomy; X-ray optics; Electronic Optical and Magnetic Materials; Condensed Matter Physics; Computer Science Applications; Computer Vision and Pattern Recognition; Applied Mathematics; Electrical and Electronic EngineeringComputer Vision and Pattern RecognitionX-ray optic
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The Association of Intraoperative driving pressure with postoperative pulmonary complications in open versus closed abdominal surgery patients – a po…

2021

Abstract Background It is uncertain whether the association of the intraoperative driving pressure (ΔP) with postoperative pulmonary complications (PPCs) depends on the surgical approach during abdominal surgery. Our primary objective was to determine and compare the association of time–weighted average ΔP (ΔPTW) with PPCs. We also tested the association of ΔPTW with intraoperative adverse events. Methods Posthoc retrospective propensity score–weighted cohort analysis of patients undergoing open or closed abdominal surgery in the ‘Local ASsessment of Ventilatory management during General Anaesthesia for Surgery’ (LAS VEGAS) study, that included patients in 146 hospitals across 29 countries.…

Driving pressure; Laparoscopic surgery; Laparoscopy; PEEP; Perioperative ventilation; Pneumoperitoneum; Protective ventilation; Respiratory mechanics;Lung DiseasesMaleLaparoscopic surgery[SDV]Life Sciences [q-bio]medicine.medical_treatmentLaparoscopic surgeryCohort StudiesPositive-Pressure RespirationPostoperative Complications0302 clinical medicinePneumoperitoneum030202 anesthesiologyPneumoperitoneumAbdomenClinical endpointPerioperative ventilationMiddle Aged3. Good healthDriving pressure Laparoscopic surgery Laparoscopy PEEP Perioperative ventilation Pneumoperitoneum Protective ventilation Respiratory mechanicsDriving pressureFemaleResearch ArticleCohort studyProtective ventilationAdultmedicine.medical_specialtyAnestesi och intensivvårdRespiratory mechanicsAnesthesia GeneralNOlcsh:RD78.3-87.303 medical and health sciencesmedicineHumansPropensity ScoreAdverse effectPEEPAgedRetrospective StudiesDriving pressure; Laparoscopic surgery; Laparoscopy; PEEP; Perioperative ventilation; Pneumoperitoneum; Protective ventilation; Respiratory mechanicsAnesthesiology and Intensive Carebusiness.industryKirurgi030208 emergency & critical care medicineOdds ratiomedicine.diseaseRespiration ArtificialSurgeryAnesthesiology and Pain Medicinelcsh:AnesthesiologyRelative riskSurgeryLaparoscopyDriving pressure ; Laparoscopic surgery ; Laparoscopy ; PEEP ; Perioperative ventilation ; Pneumoperitoneum ; Protective ventilation ; Respiratory mechanics.businessAbdominal surgery
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Protective intraoperative ventilation with higher versus lower levels of positive end-expiratory pressure in obese patients (PROBESE): study protocol…

2017

Background Postoperative pulmonary complications (PPCs) increase the morbidity and mortality of surgery in obese patients. High levels of positive end-expiratory pressure (PEEP) with lung recruitment maneuvers may improve intraoperative respiratory function, but they can also compromise hemodynamics, and the effects on PPCs are uncertain. We hypothesized that intraoperative mechanical ventilation using high PEEP with periodic recruitment maneuvers, as compared with low PEEP without recruitment maneuvers, prevents PPCs in obese patients. Methods/design The PRotective Ventilation with Higher versus Lower PEEP during General Anesthesia for Surgery in OBESE Patients (PROBESE) study is a multice…

MaleLung DiseasesTime Factors[SDV]Life Sciences [q-bio]Respiratory Medicine and Allergymedicine.medical_treatmentRESPIRATORY-DISTRESS-SYNDROMEMedicine (miscellaneous)HemodynamicsMechanical ventilation; Obesity; Positive end-expiratory pressure; Postoperative pulmonary complication; Recruitment maneuver; Medicine (miscellaneous); Pharmacology (medical)LAPAROSCOPIC BARIATRIC SURGERYLung DiseaseBody Mass Indexlaw.inventionPositive-Pressure RespirationStudy Protocol0302 clinical medicineMechanical ventilationClinical ProtocolsRandomized controlled trialRisk Factors030202 anesthesiologylawMedicine and Health SciencesClinical endpointAnesthesiaPharmacology (medical)Respiratory function030212 general & internal medicineLungLungmedicin och allergi2. Zero hungerlcsh:R5-920ddc:617Positive end-expiratory pressurerespiratory systemOperative3. Good healthTreatment OutcomeRecruitment maneuverTIDAL VOLUMESResearch DesignMechanical ventilation Positive end-expiratory pressure Recruitment maneuver Obesity Postoperative pulmonary complicationSurgical Procedures OperativeAnesthesiaBreathingFemaleErratumlcsh:Medicine (General)ALVEOLAR RECRUITMENT MANEUVERHumancirculatory and respiratory physiologymedicine.medical_specialtyTime FactorMechanical ventilation ; Obesity ; Positive end-expiratory pressure ; Postoperative pulmonary complication ; Recruitment maneuverAnesthesia GeneralLung injuryMechanical ventilation; Obesity; Positive end-expiratory pressure; Postoperative pulmonary complication; Recruitment maneuver; Body Mass Index; Clinical Protocols; Female; Humans; Intraoperative Care; Lung; Lung Diseases; Male; Obesity; Positive-Pressure Respiration; Protective Factors; Research Design; Risk Factors; Time Factors; Treatment Outcome; Anesthesia General; Surgical Procedures Operative; Medicine (miscellaneous); Pharmacology (medical)NOGENERAL-ANESTHESIADRIVING PRESSURE03 medical and health sciencesmedicineHumansddc:610ObesityClinical ProtocolGeneralProtective FactorPositive end-expiratory pressurePOSTOPERATIVE PULMONARY COMPLICATIONSMechanical ventilationSurgical ProceduresIntraoperative CareINTERNATIONAL CONSENSUSbusiness.industryRisk FactorProtective FactorsSurgeryMechanical ventilation; Obesity; Positive end-expiratory pressure; Postoperative pulmonary complication; Recruitment maneuverrespiratory tract diseasesbusinessPostoperative pulmonary complicationLUNG INJURY
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Protective ventilation with high versus low positive end-expiratory pressure during one-lung ventilation for thoracic surgery (PROTHOR): study protoc…

2018

Postoperative pulmonary complications (PPC) may result in longer duration of in-hospital stay and even mortality. Both thoracic surgery and intraoperative mechanical ventilation settings add considerably to the risk of PPC. It is unclear if one-lung ventilation (OLV) for thoracic surgery with a strategy of intraoperative high positive end-expiratory pressure (PEEP) and recruitment maneuvers (RM) reduces PPC, compared to low PEEP without RM.PROTHOR is an international, multicenter, randomized, controlled, assessor-blinded, two-arm trial initiated by investigators of the PROtective VEntilation NETwork. In total, 2378 patients will be randomly assigned to one of two different intraoperative me…

Positive-Pressure RespirationMechanical ventilation; one-lung ventilation; positive end-expiratory pressure; postoperative pulmonary complication; recruitment maneuver; thoracic surgery; Humans; Intraoperative Complications; One-Lung Ventilation; Positive-Pressure Respiration; Research Design; Sample Size; Thoracic Surgical Procedures; Randomized Controlled Trials as TopicResearch DesignSample SizeHumansCorrectionThoracic Surgical ProceduresIntraoperative ComplicationsOne-Lung VentilationRandomized Controlled Trials as TopicTrials
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