0000000000477745

AUTHOR

Antonio De Luca

0000-0002-3905-6154

showing 2 related works from this author

The Italian law on body donation: A position paper of the Italian College of Anatomists

2021

In Italy, recent legislation (Law No. 10/2020) has tuned regulations concerning the donation of one's postmortem body and tissues for study, training, and scientific research purposes. This study discusses several specific issues to optimise the applicability and effectiveness of such an important, novel regulatory setting. Some of these unsolved issues may involve the grantees of teaching and training activities, the role of academic anatomical institutes, the role of family members in the donation process, the universal time limit indicated for any donation, the handling of corpses, and the limited body donation and its subordination to the donation of organs and tissues. Critical issues …

0301 basic medicineStudents MedicalTissue and Organ ProcurementeducationTissue DonorLegislationBody donation programme Law Regulation Cadaver lab EducationCadaver labNOEducation03 medical and health sciencesBody donationAnatomistBody donation programme Law Regulation Cadaver lab EducationPolitical scienceMedicalCadaverHumansAnatomistsStudentsImplementationSettore BIO/16Body donation programmeSettore BIO/16 - Anatomia UmanaGeneral MedicineTissue DonorsTransplantationSubordination (finance)030104 developmental biologyItalyLawDonationBody donation programme; Cadaver lab; Education; Law; Regulation; Cadaver; Humans; Italy; Tissue Donors; Anatomists; Students Medical; Tissue and Organ ProcurementBody donation programme; Cadaver lab; Education; Law; RegulationPosition paperBody donation programme; Law; Regulation; Cadaver lab; Education030101 anatomy & morphologyAnatomyInefficiencyLawDevelopmental BiologyHumanRegulation
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OPLA scaffold, collagen I, and horse serum induce a higher degree of myogenic differentiation of adult rat cardiac stem cells

2009

In the last few years, a major goal of cardiac research has been to drive stem cell differentiation to replace damaged myocardium. Several research groups have attempted to differentiate potential cardiac stem cells (CSCs) using bi- or three-dimensional systems supplemented with growth factors or molecules acting as differentiating substances. We hypothesize that these systems failed to induce a complete differentiation because they lacked an architectural space. In the present study, we isolated a pool of small proliferating and fibroblast-like cells from adult rat myocardium. The phenotype of these cells was assessed and the characterized cells were cultured in a collagen I/OPLA scaffold …

SerumScaffoldPhysiologyCellular differentiationLIM-Homeodomain ProteinsClinical BiochemistryNerve Tissue ProteinsCell SeparationBiologyMuscle DevelopmentCollagen Type INestinRats Sprague-DawleyIntermediate Filament ProteinsMicroscopy Electron TransmissionTroponin TAnimalsMyocyteMyocytes CardiacHorsesTranscription factorHomeodomain ProteinsMyosin Heavy ChainsTissue ScaffoldsSettore BIO/16 - Anatomia UmanaMyocardiumCell DifferentiationCell BiologyAnatomyNestinPhenotypestem cell OPLA scaffoldActinsIn vitroClone CellsGATA4 Transcription FactorRatsCell biologyAdult Stem CellsProto-Oncogene Proteins c-kitConnexin 43FemaleStem cellTranscription FactorsJournal of Cellular Physiology
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