0000000000480900

AUTHOR

Eugenio Gimenez

showing 3 related works from this author

The kinetics of torque teno virus plasma DNA load shortly after engraftment predicts the risk of high-level CMV DNAemia in allogeneic hematopoietic s…

2018

Monitoring Torque teno virus (TTV) DNA load helps to estimate the risk of opportunistic infections in solid organ transplant recipients. We investigated whether the early kinetic pattern of plasma TTV DNA load after allogeneic hematopoietic stem cell transplantation (allo-HSCT) associates with subsequent CMV and EBV DNAemia. This study included 71 allo-HSCT patients. We found that the area under the curve (AUC) for log10 TTV DNA loads quantified by days 20 and 30 after transplantation (TTV DNA load AUC20-30), was significantly lower (P=0.036) in patients who subsequently developed CMV DNAemia requiring preemptive antiviral therapy (n=17) than in those who did not (n=8) or had no CMV DNAemia…

Male0301 basic medicineTorque teno virusTransplantation Conditioningmedicine.medical_treatment030106 microbiologyHematopoietic stem cell transplantation03 medical and health sciencesInterferonmedicineHumansRetrospective StudiesTorque teno virusTransplantationbusiness.industryHematopoietic Stem Cell TransplantationArea under the curvevirus diseasesHematologyCmv dnaemiaVirologyTransplantation030104 developmental biologyHematology; TransplantationCytomegalovirus InfectionsDNA ViralImmunologyFemaleTransplantation ConditioningbusinessCD8medicine.drugBone Marrow Transplantation
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When should preemptive antiviral therapy for active CMV infection be withdrawn from allogeneic stem cell transplant recipients?

2017

When should preemptive antiviral therapy for active CMV infection be withdrawn from allogeneic stem cell transplant recipients?

AdultMaleAdolescentCongenital cytomegalovirus infectionCytomegalovirusHematologic Neoplasms03 medical and health sciences0302 clinical medicinemedicineHumansProspective StudiesProgenitor cellProspective cohort studyAgedTransplantationbusiness.industryAntiviral therapyHematologyMiddle Agedmedicine.diseaseAllograftsTransplantationGraft-versus-host disease030220 oncology & carcinogenesisHematologic NeoplasmsImmunologyCytomegalovirus InfectionsFemaleStem cellbusiness030215 immunologyStem Cell TransplantationBone marrow transplantation
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Preemptive antiviral therapy for CMV infection in allogeneic stem cell transplant recipients guided by the viral doubling time in the blood

2015

Preemptive antiviral therapy for CMV infection in allogeneic stem cell transplant recipients guided by the viral doubling time in the blood

AdultMale0301 basic medicineAdolescent030106 microbiologyCytomegalovirusVirus ReplicationAntiviral AgentsYoung Adult03 medical and health sciences0302 clinical medicineHumansTransplantation HomologousMedicineDoubling timeProgenitor cellGanciclovirAgedTransplantationbusiness.industryHematopoietic Stem Cell TransplantationAntiviral therapyHematologyMiddle Agedmedicine.diseaseTransplantationGraft-versus-host diseaseCytomegalovirus InfectionsDNA ViralImmunologyFemaleStem cellbusiness030215 immunologyBone Marrow Transplantation
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