0000000000481794

AUTHOR

Ahmad R. Hariri

showing 3 related works from this author

Dopamine in amygdala gates limbic processing of aversive stimuli in humans

2008

Dopamine is known to contribute to the amygdala-mediated aversive response, where increased dopamine release can augment amygdala function. Combining fMRI and PET imaging techniques, Kienast et al. present findings that suggest a functional link between anxiety temperament, dopamine storage capacity and emotional processing in the amygdala. Dopamine is released under stress and modulates processing of aversive stimuli. We found that dopamine storage capacity in human amygdala, measured with 6-[18F]fluoro-L-DOPA positron emission tomography, was positively correlated with functional magnetic resonance imaging blood oxygen level–dependent signal changes in amygdala and dorsal anterior cingula…

AdultMaleFluorine RadioisotopesDopamineBrain mappingAmygdalaGyrus CinguliDopaminemedicineImage Processing Computer-AssistedLimbic SystemPsychophysicsHumansAnterior cingulate cortexSystems neuroscienceBrain Mappingmedicine.diagnostic_testGeneral NeuroscienceMiddle AgedAmygdalaMagnetic Resonance ImagingDihydroxyphenylalanineFunctional imagingOxygenAffectmedicine.anatomical_structurenervous systemPositron-Emission TomographyAversive StimulusFunctional magnetic resonance imagingPsychologyNeurosciencepsychological phenomena and processesmedicine.drug
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Building Bridges through Science

2017

WOS: 000415310800007 PubMed ID: 29144972 Science is ideally suited to connect people from different cultures and thereby foster mutual understanding. To promote international life science collaboration, we have launched "The Science Bridge'' initiative. Our current project focuses on partnership between Western and Middle Eastern neuroscience communities. Medical Research Council [MC_UP_1202/5]

Historyhistory 15th centuryhistory 21st centuryhistory medievalInternational CooperationNeurophysiologyEurope; history 15th century; history 21st century; history ancient; history medieval; humans; middle east; neurosciences; international cooperation; neuroscience (all)Bridge (interpersonal)History 21st CenturyAncient03 medical and health sciencesMiddle East0302 clinical medicinehistory ancientPolitical scienceHumansThrough ScienceHistory AncientHistory 15th CenturyEurope; History 15th Century; History 21st Century; History Ancient; History Medieval; Humans; Middle East; Neurosciences; International Cooperation; Neuroscience (all)Neuroscience (all)General NeuroscienceBuilding BridgesNeurosciences21st CenturyHistory Medieval030227 psychiatry3. Good healthEurope15th CenturyGeneral partnershipEngineering ethics030217 neurology & neurosurgeryMedieval
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Dopamine-modulated aversive emotion processing fails in alcohol-dependent patients.

2013

Negative mood states after alco- hol detoxifi cation may enhance the relapse risk. As recently shown in healthy volunteers, dopamine storage capacity ( V d ) in the left amy- gdala was positively correlated with functional activation in the left amygdala and anterior cin- gulate cortex (ACC) during an emotional task; high functional connectivity between the amy- gdala and the ACC, a region important for emo- tion regulation, was associated with low trait anxiety. Based on these fi ndings, we now tested whether detoxifi ed alcohol-dependent patients have a disrupted modulation of the anterior cin- gulate cortex activation in response to aversive stimuli by amygdala dopamine. Furthermore, we …

AdultMaleDopamineEmotionsAnxietyAmygdalaNeuroimagingDopaminemedicineImage Processing Computer-AssistedHumansPharmacology (medical)Cerebral Cortexmedicine.diagnostic_testSmokingMagnetic resonance imagingGeneral MedicineAmygdalaMagnetic Resonance ImagingCortex (botany)Diagnostic and Statistical Manual of Mental DisordersPsychiatry and Mental healthAffectAlcoholismmedicine.anatomical_structurePositron emission tomographyPositron-Emission TomographyAnxietyFemalemedicine.symptomAversive StimulusRadiopharmaceuticalsPsychologyNeurosciencepsychological phenomena and processesPhotic Stimulationmedicine.drugPharmacopsychiatry
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