0000000000482095

AUTHOR

Harald Löffler

0000-0002-2017-8469

showing 5 related works from this author

The MOAHLFA index of irritant sodium lauryl sulfate reactions: first results of a multicentre study on routine sodium lauryl sulfate patch testing

2004

In a multicentre study of the German Contact Dermatitis Research Group, sodium lauryl sulfate (SLS) 0.25% and 0.5% aq. has been added to routine allergen patch tests to assess its properties as a convenient diagnostic indicator of individual susceptibility to irritation at the time of patch testing. Previous studies indicated that irritant SLS reactivity may be related to individual factors such as age and sex. As these factors are, in turn, among the important predictors of contact allergy to many allergens, e.g. summarized in the 'MOAHLFA index', the impact of the MOAHLFA factors on irritant SLS patch test reactivity, and thus a potential for confounding, was assessed in the 5971 particip…

AdultMalemedicine.medical_specialtyTime FactorsHand DermatosesDermatologyLeg Dermatosesmedicine.disease_causeLogistic regressionSeverity of Illness IndexDermatitis Atopic030207 dermatology & venereal diseases03 medical and health sciencesSex Factors0302 clinical medicineAllergenRisk FactorsmedicineHumansImmunology and AllergyRisk factorintegumentary systemChemistryConfoundingAge FactorsSodium Dodecyl SulfatePatch testConfounding Factors EpidemiologicPatch Testsmedicine.diseaseDermatology3. Good healthSurgeryDermatitis Occupational030220 oncology & carcinogenesisToxicityIrritantsDermatitis IrritantFemaleDisease SusceptibilityIrritationContact dermatitisFacial DermatosesContact Dermatitis
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The concentration of para-phenylenediamine (PPD) for routine patch testing in a standard series needs to be redefined

2005

medicine.medical_specialtyPediatricsDose-Response Relationship Drugbusiness.industryDermatologyPatch TestsPhenylenediaminesPara phenylenediamineDermatologyPatch testing030207 dermatology & venereal diseases03 medical and health sciences0302 clinical medicineGermany030220 oncology & carcinogenesisDermatitis Allergic ContactmedicineHumansImmunology and AllergyColoring AgentsbusinessContact Dermatitis
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Chromated metal products may be hazardous to patients with chromate allergy.

2009

Background:  Hidden allergen exposure may contribute to persistence and relapse of chromate dermatitis. According to case reports, chromated metal products, such as screws, fittings, etc., may be relevant allergen sources for patients sensitized to chromate. Objectives:  To examine concomitant patch test reactivity to potassium dichromate 0.5% petrolatum (pet.) and three different types of chromated metal rings. Patients/Methods:  Patients with proven or suspected chromate allergy were patch tested with potassium dichromate 0.5% pet. and three different types of chromated metal rings (yellow, olive, and black). Hexavalent chromium Cr(VI) release from the patch tested rings was chemically an…

AdultChromiumMaleAllergyDermatologyMetal030207 dermatology & venereal diseases03 medical and health scienceschemistry.chemical_compound0302 clinical medicineChromium CompoundsGermanymedicineImmunology and AllergyHumansIn patientHexavalent chromium030223 otorhinolaryngologyPotassium dichromateChromate conversion coatingMetallurgyPatch testAllergensMiddle AgedPatch Testsmedicine.disease3. Good healthchemistryvisual_artDermatitis Allergic Contactvisual_art.visual_art_mediumFemalePotassium DichromateContact dermatitisNuclear chemistryContact dermatitis
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Late reactions to patch test preparations with reduced concentrations of p-phenylenediamine : a multicentre investigation of the German Contact Derma…

2011

Background. p-Phenylenediamine (PPD) 1% in petrolatum has been shown in a prospective study to elicit late reactions in 1.5% of routine patch tests, which may be indicative of patch test sensitization. Objectives. To assess the frequency of late reactions to reduced PPD patch test concentrations. Methods. In 1838 patients, PPD was tested at three concentrations (0.5% pet., group I; 0.4% pet., group II; and 0.35% pet., group III). Patch tests were read on D1 (D2) to D3 (D4); additional late readings were performed on D7, D14, and D21. Patients who were not able to return for all scheduled late readings were telephoned on D7, D14, and D21, and questioned about a reaction at the patch test sit…

AdultMalemedicine.medical_specialtyAllergyTime FactorsMedizinDermatologyPhenylenediaminesGastroenterology030207 dermatology & venereal diseases03 medical and health scienceschemistry.chemical_compoundYoung Adult0302 clinical medicineImmunopathologyInternal medicineImmunology and AllergyMedicineHumans030212 general & internal medicineProspective cohort studySensitizationbusiness.industryPatch testp-PhenylenediamineMiddle AgedPatch Testsmedicine.disease3. Good healthSurgerymedicine.anatomical_structurechemistryPatch test sensitizationDermatitis Allergic ContactFemalebusinessContact dermatitis
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Very late reactions in the patch test with fragrance mix I and oak moss absolute (Evernia prunastri, INCI): Data of the Information Network of Depart…

2022

medicine.medical_specialtyTime Factors610 Medicine & healthDermatology030207 dermatology & venereal diseases03 medical and health sciences0302 clinical medicineActive sensitizationmedicineImmunology and AllergyHumansddc:610610 Medicine & healthFragrance mixAllergic contact dermatitisbiologybusiness.industryParmeliaceaePatch testAbsolute (perfumery)AllergensPatch Testsmedicine.diseasebiology.organism_classificationMossDermatology030228 respiratory systemOdorantsbusiness
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