0000000000485120
AUTHOR
D. De Argila
Determination of Minimal Erythema Dose and Anomalous Reactions to UVA Radiation by Skin Phototype
Background: Phototesting is a technique that assesses the skin’s sensitivity to UV radiation by determining the smallest dose of radiation capable of inducing erythema (minimal erythema dose [MED]) and anomalous responses to UV-A radiation. No phototesting protocol guidelines have been published to date. Methodology: This was a multicenter prospective cohort study in which 232 healthy volunteers were recruited at 9 hospitals. Phototests were carried out with solar simulators or fluorescent broadband UV-B lamps. Each individual received a total of 5 or 6 incremental doses of erythemal radiation and 4 doses of UV-A radiation. The results were read at 24 hours. Results: At hospitals where sola…
Determinación de la dosis eritemática mínima y reacciones anómalas a radiación ultravioleta A según fototipo
Resumen Antecedentes La tecnica del fototest evalua la sensibilidad de la piel a la radiacion ultravioleta (RUV) mediante la determinacion de la minima dosis de radiacion capaz de producir eritema (dosis minima eritematica [DEM]) y la respuesta anomala a UVA. No existen guias protocolizadas para la tecnica del fototest. Metodologia Estudio multicentrico de cohortes prospectivo. Un total de 232 voluntarios sanos fueron reclutados en 9 centros hospitalarios. El fototest se realizo con simuladores solares (SS) o lamparas fluorescentes de UVB de banda ancha (UVBBA). Cada sujeto recibio un total de 5 o 6 dosis progresivas de radiacion eritematica y 4 dosis de UVA. La lectura se realizo a las 24 …