6533b821fe1ef96bd127b68d
RESEARCH PRODUCT
Determination of Minimal Erythema Dose and Anomalous Reactions to UVA Radiation by Skin Phototype
J.m. CarrrascosaMario LechaJosé A. Martínez-lozanoA. Pérez FerriolsM.a. BarnadasP. AguileraYolanda SolaJerónimo LorenteX. De CaboMaría P. UtrillasJosé AguileraJesús GardeazabalM.t. Rodríguez GranadosM.v. De Gálvez ArandaAna Giménez-arnauD. De Argilasubject
medicine.medical_specialtyHistologyintegumentary systemErythemaUVA Radiationbusiness.industryDermatologyPhototypeDermatologyPathology and Forensic MedicineSurgeryMinimal erythema doseHealthy volunteersmedicinePhototestingmedicine.symptombusinessProspective cohort studydescription
Background: Phototesting is a technique that assesses the skin’s sensitivity to UV radiation by determining the smallest dose of radiation capable of inducing erythema (minimal erythema dose [MED]) and anomalous responses to UV-A radiation. No phototesting protocol guidelines have been published to date. Methodology: This was a multicenter prospective cohort study in which 232 healthy volunteers were recruited at 9 hospitals. Phototests were carried out with solar simulators or fluorescent broadband UV-B lamps. Each individual received a total of 5 or 6 incremental doses of erythemal radiation and 4 doses of UV-A radiation. The results were read at 24 hours. Results: At hospitals where solar simulators were used, the mean (SD) MED values were 23 (8), 28 (4), 35 (4), and 51 (6) mJ/cm 2 for skin phototypes i to iv, respectively. At hospitals where
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2014-10-01 | Actas Dermo-Sifiliográficas (English Edition) |