0000000000299534
AUTHOR
Mario Lecha
showing 3 related works from this author
A European multicentre photopatch test study
2012
The two most common agent groups currently responsible for photoallergic contact dermatitis (PACD) are organic ultraviolet (UV) absorbers in sunscreens and topical nonsteroidal anti-inflammatory drugs (NSAIDs). However, availability of information on the photoallergenic potential of these agents is scarce.To obtain current information on the frequency of PACD to 19 organic UV absorbers and five topical NSAIDs, including newer agents, in common usage in Europe.A prospective, multicentre photopatch test study was conducted with 1031 patients attending for investigation of suspected PACD in 30 centres across 12 European countries.A total of 346 PACD reactions in 200 (19·4%) subjects occurred. …
Determination of Minimal Erythema Dose and Anomalous Reactions to UVA Radiation by Skin Phototype
2014
Background: Phototesting is a technique that assesses the skin’s sensitivity to UV radiation by determining the smallest dose of radiation capable of inducing erythema (minimal erythema dose [MED]) and anomalous responses to UV-A radiation. No phototesting protocol guidelines have been published to date. Methodology: This was a multicenter prospective cohort study in which 232 healthy volunteers were recruited at 9 hospitals. Phototests were carried out with solar simulators or fluorescent broadband UV-B lamps. Each individual received a total of 5 or 6 incremental doses of erythemal radiation and 4 doses of UV-A radiation. The results were read at 24 hours. Results: At hospitals where sola…
Determinación de la dosis eritemática mínima y reacciones anómalas a radiación ultravioleta A según fototipo
2014
Resumen Antecedentes La tecnica del fototest evalua la sensibilidad de la piel a la radiacion ultravioleta (RUV) mediante la determinacion de la minima dosis de radiacion capaz de producir eritema (dosis minima eritematica [DEM]) y la respuesta anomala a UVA. No existen guias protocolizadas para la tecnica del fototest. Metodologia Estudio multicentrico de cohortes prospectivo. Un total de 232 voluntarios sanos fueron reclutados en 9 centros hospitalarios. El fototest se realizo con simuladores solares (SS) o lamparas fluorescentes de UVB de banda ancha (UVBBA). Cada sujeto recibio un total de 5 o 6 dosis progresivas de radiacion eritematica y 4 dosis de UVA. La lectura se realizo a las 24 …