0000000000485925
AUTHOR
Elex Hill
Additional file 1 of The prevalence of onchocerciasis in Africa and Yemen, 2000–2018: a geospatial analysis
Additional file 1: Supplementary Appendix. This file contains a GATHER compliance checklist, a list of data sources used in the present analysis, and further details of the analytical methodology and results.
Predicting the environmental suitability for onchocerciasis in Africa as an aid to elimination planning
Recent evidence suggests that, in some foci, elimination of onchocerciasis from Africa may be feasible with mass drug administration (MDA) of ivermectin. To achieve continental elimination of transmission, mapping surveys will need to be conducted across all implementation units (IUs) for which endemicity status is currently unknown. Using boosted regression tree models with optimised hyperparameter selection, we estimated environmental suitability for onchocerciasis at the 5 × 5-km resolution across Africa. In order to classify IUs that include locations that are environmentally suitable, we used receiver operating characteristic (ROC) analysis to identify an optimal threshold for suitabil…