0000000000489602

AUTHOR

Peter J. Hylands

showing 3 related works from this author

Ethnobotanical survey and cytotoxicity testing of plants of South-western Nigeria used to treat cancer, with isolation of cytotoxic constituents from…

2010

Abstract Ethnopharmacological relevance There is only scant literature on the anticancer components of medicinal plants from Nigeria, yet traditional healers in the area under study claim to have been managing the disease in their patients with some success using the species studied. Aim of study To document plants commonly used to treat cancer in South-western Nigeria and to test the scientific basis of the claims using in vitro cytotoxicity tests. Methods Structured questionnaires were used to explore the ethnobotanical practices amongst the traditional healers. Methanol extracts of the most common species cited were screened for cytotoxicity using the sulforhodamine B (SRB) assay in both…

MalePycnanthus angolensisEthnobotanyNigeriaPharmacognosyCajanusCajanusCell Line TumorNeoplasmsDrug DiscoveryMedicineHumansOleanolic AcidCytotoxicityMedicinal plantsPharmacologyPlants MedicinalbiologyTraditional medicinebusiness.industryData CollectionCancerPlantsbiology.organism_classificationmedicine.diseaseSitosterolsPlant LeavesAcanthospermum hispidumCancer cellEthnopharmacologyFlavanonesbusinessJournal of ethnopharmacology
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Traditional Chinese medicine research in the post-genomic era: good practice, priorities, challenges and opportunities.

2012

Abstract Background and aims GP-TCM is the 1st EU-funded Coordination Action consortium dedicated to traditional Chinese medicine (TCM) research. This paper aims to summarise the objectives, structure and activities of the consortium and introduces the position of the consortium regarding good practice, priorities, challenges and opportunities in TCM research. Serving as the introductory paper for the GP-TCM Journal of Ethnopharmacology special issue, this paper describes the roadmap of this special issue and reports how the main outputs of the ten GP-TCM work packages are integrated, and have led to consortium-wide conclusions. Materials and methods Literature studies, opinion polls and di…

medicine.medical_specialtyBiomedical ResearchCollaborative networkMEDLINEAlternative medicineAcupuncture TherapyOmicsGuidelines as TopicGuidelines03 medical and health sciencesPharmacovigilance0302 clinical medicineTraditional Chinese medicineDrug Discoverymedicinemedia_common.cataloged_instanceHumansEuropean UnionEuropean unionCooperative BehaviorMedicine Chinese Traditional030304 developmental biologyGrand Challengesmedia_commonGP-TCMPharmacology0303 health sciencesIntegrative MedicineEvidence-Based MedicineTraditional medicinebusiness.industrySystems BiologyAcupunctureEvidence-based medicineGenomics3. Good health030220 oncology & carcinogenesisEngineering ethicsIntersectoral CollaborationIntegrative medicineChinese herbal medicinebusinessDrugs Chinese HerbalPhytotherapyJournal of ethnopharmacology
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Omic techniques in systems biology approaches to traditional Chinese medicine research: present and future.

2012

AbstractOmic techniques have become key tools in the development of systems biology. As the holistic approaches underlying the practice of traditional Chinese medicine (TCM) and new tendencies in Western medicine towards personalised medicine require in-depth knowledge of mechanisms of action and active compounds, the use of omic techniques is crucial for understanding and interpretation of TCM development, especially in view of its expansion in Western countries. In this short review, omic applications in TCM research are reviewed which has allowed some speculation regarding future perspectives for these approaches in TCM modernisation and standardisation. Guidelines for good practice for …

ProteomicsBiomedical ResearchSystems biologyHerbal MedicineMEDLINETraditional Chinese medicineBioinformatics03 medical and health sciencesTraditional Chinese medicine0302 clinical medicineChinese traditionalDrug DiscoveryMetabolomicsMedicineHumansTechnology PharmaceuticalMedicine Chinese TraditionalPrecision MedicineTranscriptomicsGood practice030304 developmental biologyPharmacology0303 health sciencesPlants Medicinalbusiness.industrySystems BiologyGenomicsData science3. Good healthMetabonomics030220 oncology & carcinogenesisChinese herbal medicinebusinessWestern medicineDrugs Chinese HerbalPhytotherapyJournal of ethnopharmacology
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