6533b856fe1ef96bd12b2607

RESEARCH PRODUCT

Omic techniques in systems biology approaches to traditional Chinese medicine research: present and future.

Enrica BosisioJavier Lucio-cazanaMaría Laura García-bermejoXuebin DongPeter J. HylandsQihe XuNoelia TejedorMaria CarraraHuige LiMonique S. J. SimmondsAlessandro Buriani

subject

ProteomicsBiomedical ResearchSystems biologyHerbal MedicineMEDLINETraditional Chinese medicineBioinformatics03 medical and health sciencesTraditional Chinese medicine0302 clinical medicineChinese traditionalDrug DiscoveryMetabolomicsMedicineHumansTechnology PharmaceuticalMedicine Chinese TraditionalPrecision MedicineTranscriptomicsGood practice030304 developmental biologyPharmacology0303 health sciencesPlants Medicinalbusiness.industrySystems BiologyGenomicsData science3. Good healthMetabonomics030220 oncology & carcinogenesisChinese herbal medicinebusinessWestern medicineDrugs Chinese HerbalPhytotherapy

description

AbstractOmic techniques have become key tools in the development of systems biology. As the holistic approaches underlying the practice of traditional Chinese medicine (TCM) and new tendencies in Western medicine towards personalised medicine require in-depth knowledge of mechanisms of action and active compounds, the use of omic techniques is crucial for understanding and interpretation of TCM development, especially in view of its expansion in Western countries. In this short review, omic applications in TCM research are reviewed which has allowed some speculation regarding future perspectives for these approaches in TCM modernisation and standardisation. Guidelines for good practice for the application of omics in TCM research are also proposed.

10.1016/j.jep.2012.01.055https://pubmed.ncbi.nlm.nih.gov/22342380