0000000000489799

AUTHOR

Philip C. Calder

0000-0002-6038-710x

showing 2 related works from this author

Gut microbiota and osteoarthritis management: An expert consensus of the European society for clinical and economic aspects of osteoporosis, osteoart…

2019

Berenbaum, Francis/0000-0001-8252-7815; Dennison, Elaine/0000-0002-3048-4961; Bindels, Laure B./0000-0003-3747-3234; Cooper, Cyrus/0000-0003-3510-0709 WOS:000491638300002 PubMed ID: 31437484 The prevalence of osteoarthritis (OA) increases not only because of longer life expectancy but also because of the modern lifestyle, in particular physical inactivity and diets low in fiber and rich in sugar and saturated fats, which promote chronic low-grade inflammation and obesity. Adverse alterations of the gut microbiota (GMB) composition, called microbial dysbiosis, may favor metabolic syndrome and inflammaging, two important components of OA onset and evolution. Considering the burden of OA and t…

0301 basic medicineAgingmedicine.medical_specialtyOsteoporosisPsychological interventionOsteoarthritisGut microbiotaGut floraDysbiosis; Gut microbiota; Inflammaging; Modern diet; Obesity; OsteoarthritisBiochemistry03 medical and health sciences0302 clinical medicineOsteoarthritismedicineAnimalsHumansMusculoskeletal DiseasesObesityModern dietIntensive care medicineMolecular BiologySocieties MedicalInflammationbiologybusiness.industrymedicine.diseasebiology.organism_classificationObesityInflammagingDysbiosiInflammaging ObesityGastrointestinal MicrobiomeEurope030104 developmental biologyNeurologyOsteoporosisDysbiosisObservational studyOsteoarthritiMetabolic syndromebusinessDysbiosis030217 neurology & neurosurgeryBiotechnology
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Red Blood Cell Eicosapentaenoic Acid Inversely Relates to MRI-Assessed Carotid Plaque Lipid Core Burden in Elders at High Cardiovascular Risk

2017

Supplemental marine omega-3 eicosapentaenoic acid (EPA) has an anti-atherosclerotic effect. Clinical research on EPA supplied by the regular diet and atherosclerosis is scarce. In the framework of the PREvención con DIeta MEDiterránea (PREDIMED) trial, we conducted a cross-sectional study in 161 older individuals at high vascular risk grouped into different stages of carotid atherosclerosis severity, including those without ultrasound-detected atheroma plaque (n = 38), with plaques <2.0 mm thick (n = 65), and with plaques ≥2.0 mm (n = 79). The latter were asked to undergo contrast-enhanced 3T magnetic resonance imaging (MRI) and were subsequently grouped into absence (n = 31) or presence (n…

Carotid Artery DiseasesMalePathologyErythrocytes030204 cardiovascular system & hematologyCarotid Intima-Media Thicknessatherosclerosis; diet; fish; imaging; omega-3Body Mass Indexchemistry.chemical_compound0302 clinical medicineRisk Factors030212 general & internal medicinechemistry.chemical_classificationNutrition and Dieteticsmedicine.diagnostic_testimagingMiddle AgedMagnetic Resonance ImagingEicosapentaenoic acidPlaque AtheroscleroticCholesterolmedicine.anatomical_structureEicosapentaenoic AcidCardiovascular DiseasesCardiologyFemalelipids (amino acids peptides and proteins)Internal carotid arteryomega-3lcsh:Nutrition. Foods and food supplymedicine.medical_specialtylcsh:TX341-641Article03 medical and health sciencesmedicine.arteryInternal medicinemedicineHumansTriglyceridesAgedfishCholesterolbusiness.industryFatty acidMagnetic resonance imagingmedicine.diseaseRed blood cellCross-Sectional StudiesNutrition AssessmentAtheromachemistryatherosclerosisbusinessdietBody mass indexBiomarkersFood ScienceNutrients
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