showing 5 related works from this author
Selection of the Optimal Algorithm for Real-Time Estimation of Beta Band Power during DBS Surgeries in Patients with Parkinson's Disease
2017
Deep Brain Stimulation (DBS) is a surgical procedure for the treatment of motor disorders in patients with Parkinson’s Disease (PD). DBS involves the application of controlled electrical stimuli to a given brain structure. The implantation of the electrodes for DBS is performed by a minimally invasive stereotactic surgery where neuroimaging and microelectrode recordings (MER) are used to locate the target brain structure. The Subthalamic Nucleus (STN) is often chosen for the implantation of stimulation electrodes in DBS therapy. During the surgery, an intraoperative validation is performed to locate the dorsolateral region of STN. Patients with PD reveal a high power in the β band (frequenc…
Feature selection for KNN classifier to improve accurate detection of subthalamic nucleus during deep brain stimulation surgery in Parkinson’s patien…
2017
The tremor and dystonia associated with Parkinson’s disease can be treated with deep brain stimulation (DBS) implanted into the subthalamic nucleus (STN). The accurate STN detection is a complex neurosurgeon task during a DBS surgery since a proper fixing of stimulating electrodes will impact on the patient’s future life. The brain electrical signals obtained with Micro Electrodes Register (MER) are acquired at different depths of the brain during DBS surgery to detect STN. In our previous work, we found good accuracy performance to improve the localization of STN using K-Nearest Neighbours (KNN) supervised learning algorithm. However, for real-time classification, it is essential to reduce…
Optimization of the KNN Supervised Classification Algorithm as a Support Tool for the Implantation of Deep Brain Stimulators in Patients with Parkins…
2019
Deep Brain Stimulation (DBS) of the Subthalamic Nuclei (STN) is the most used surgical treatment to improve motor skills in patients with Parkinson&rsquo
STN area detection using K-NN classifiers for MER recordings in Parkinson patients during neurostimulator implant surgery
2016
Deep Brain Stimulation (DBS) applies electric pulses into the subthalamic nucleus (STN) improving tremor and other symptoms associated to Parkinson's disease. Accurate STN detection for proper location and implant of the stimulating electrodes is a complex task and surgeons are not always certain about final location. Signals from the STN acquired during DBS surgery are obtained with microelectrodes, having specific characteristics differing from other brain areas. Using supervised learning, a trained model based on previous microelectrode recordings (MER) can be obtained, being able to successfully classify the STN area for new MER signals. The K Nearest Neighbours (K-NN) algorithm has bee…
Determinación mediante minería de datos del núcleo subtalámico utilizando registros MER de cirugías para la implantación de neuroestimuladores en pac…
2018
La enfermedad de Parkinson (EP) es una degeneración del sistema nervioso central (SNC) caracterizada por un deterioro progresivo de funciones motoras como lentitud de movimientos, temblor, rigidez e inestabilidad postura. Un estimulador cerebral profundo (DBS por sus siglas en inglés) es una tecnología novedosa para el tratamiento de los trastornos motores de la EP en los casos donde la medicación no es efectiva o cuando dichos fármacos generan efectos secundarios muy discapacitantes como las discenesias. Básicamente el DBS consiste en un neuroestimulador implantado o marcapasos del cerebro que mediante 2 microelectrodos estimula con pulsos de alta frecuencia al núcleo subtalámico (STN por …