0000000000497016

AUTHOR

Aurelio Secinaro

0000-0002-2611-8061

showing 6 related works from this author

Covid-19 and Congenital Heart Disease: results from a nationwide survey

2020

Background. The pandemic of Novel Coronavirus Disease 2019 (COVID-19) is challenging, given the large number of hospitalized patients. Cardiovascular co-morbidities are linked to a higher mortality risk. Thus, patients with Congenital Heart Disease (CHD) might represent a high-risk population. Nevertheless, no data about them are available, yet. Hence, we conducted a nationwide survey to assess clinical characteristics and outcomes in patients with congenital heart disease affected by COVID-19. Methods and Results. This is a multi-centre, observational, nationwide survey, involving high-volume Italian CHD centres. COVID-19 diagnosis was defined as either &ldquo

medicine.medical_specialtyHeart diseasePopulationcardiovascular complicationslcsh:Medicine030204 cardiovascular system & hematologyChest painArticle03 medical and health sciences0302 clinical medicineDiabetes mellitusInternal medicinecongenital heart disease COVID-19 cardiovascular complicationsmedicinePalpitations030212 general & internal medicineeducationStrokecardiovascular complicationeducation.field_of_studybusiness.industrylcsh:Rcongenital heart disease; COVID-19; cardiovascular complicationsCOVID-19General Medicinemedicine.diseasecongenital heart diseaseHeart failureCohortmedicine.symptombusiness
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Kawasaki disease: Guidelines of Italian Society of Pediatrics, part II - Treatment of resistant forms and cardiovascular complications, follow-up, li…

2018

Abstract This second part of practical Guidelines related to Kawasaki disease (KD) has the goal of contributing to prompt diagnosis and most appropriate treatment of KD resistant forms and cardiovascular complications, including non-pharmacologic treatments, follow-up, lifestyle and prevention of cardiovascular risks in the long-term through a set of 17 recommendations. Guidelines, however, should not be considered a norm that limits the treatment options of pediatricians and practitioners, as treatment modalities other than those recommended may be required as a result of peculiar medical circumstances, patient’s condition, and disease severity or individual complications.

MaleDrug ResistanceReviewCoronary Artery Disease030204 cardiovascular system & hematologySeverity of Illness IndexCoronary artery diseaseEfficacy0302 clinical medicineCardiovascular Diseasecoronary artery abnormalitiesChildCoronary artery abnormalitieSocieties MedicalPediatricAnti-Inflammatory Agents Non-Steroidallcsh:RJ1-570Immunoglobulins IntravenousSettore MED/38Settore MED/38 - PEDIATRIA GENERALE E SPECIALISTICACardiovascular DiseasesInnovative biotechnologieChild PreschoolPractice Guidelines as TopicFemaleRisk assessmentmedicine.drugHumanmedicine.medical_specialtypediatricsMucocutaneous Lymph Node SyndromeRisk AssessmentFollow-Up Studie03 medical and health sciencesinnovative biotechnologies030225 pediatricsDiabetes mellitusSeverity of illnessmedicineHumansIntensive care medicineIntravenous immunoglobulinAspirinKawasaki diseasebusiness.industryWarfarinlcsh:Pediatricsmedicine.diseasePersonalized medicineInfliximabAspirin; Child; Coronary artery abnormalities; Innovative biotechnologies; Intravenous immunoglobulin; Kawasaki disease; Personalized medicine;Immunoglobulins IntravenouPediatrics Perinatology and Child Healthperinatology and child healthKawasaki diseaseaspirin; child; coronary artery abnormalities; innovative biotechnologies; intravenous immunoglobulin; Kawasaki disease; personalized medicine; pediatrics perinatology and child healthbusinessFollow-Up Studies
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Kawasaki disease: guidelines of the Italian Society of Pediatrics, part I - definition, epidemiology, etiopathogenesis, clinical expression and manag…

2018

Abstract The primary purpose of these practical guidelines related to Kawasaki disease (KD) is to contribute to prompt diagnosis and appropriate treatment on the basis of different specialists’ contributions in the field. A set of 40 recommendations is provided, divided in two parts: the first describes the definition of KD, its epidemiology, etiopathogenetic hints, presentation, clinical course and general management, including treatment of the acute phase, through specific 23 recommendations. Their application is aimed at improving the rate of treatment with intravenous immunoglobulin and the overall potential development of coronary artery abnormalities in KD. Guidelines, however, should…

MalePediatricsReviewPediatricsSeverity of Illness Index0302 clinical medicineRetrospective StudieEpidemiology030212 general & internal medicineDisease management (health)Coronary artery abnormalitieChildrenSocieties MedicalRandomized Controlled Trials as TopicPediatriclcsh:RJ1-570Disease ManagementImmunoglobulins IntravenousGeneral MedicinePrognosisSettore MED/38Treatment OutcomeSettore MED/38 - PEDIATRIA GENERALE E SPECIALISTICAItalyMeta-analysisAcute DiseasePractice Guidelines as TopicDisease ProgressionFemaleCoronary artery abnormalitiesAspirin; Children; Coronary artery abnormalities; Intravenous immunoglobulin; Kawasaki disease;Humanmedicine.medical_specialtyPrognosiMucocutaneous Lymph Node SyndromeRisk Assessment03 medical and health sciences030225 pediatricsSeverity of illnessmedicineHumansRisk factorIntravenous immunoglobulinRetrospective Studiesaspirin; children; coronary artery abnormalities; intravenous immunoglobulin; Kawasaki disease; pediatrics perinatology and child healthAspirinKawasaki diseasebusiness.industrylcsh:PediatricsRetrospective cohort studymedicine.diseaseImmunoglobulins IntravenouPediatrics Perinatology and Child Healthperinatology and child healthKawasaki diseaseDifferential diagnosisbusiness
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Right/Left Ventricular Blood Pool T2 Ratio as an Innovative Cardiac MRI Screening Tool for the Identification of Left‐to‐Right Shunts in Patients Wit…

2021

Background Left-to-right (L-R) shunts are characterized by a pathological connection between high- and low-pressure systems, leading to a mixing of oxygen-rich blood with low oxygenated blood. They are typically diagnosed by phase-contrast cardiac magnetic resonance imaging (MRI) which requires extensive planning. T2 is sensitive to blood oxygenation and may be able to detect oxygenation differences between the left (LV) and right ventricles (RV) caused by L-R shunts. Purpose To test the feasibility of routine T2 mapping to detect L-R shunts. Study type Retrospective. Population Patients with known L-R shunts (N = 27), patients with RV disease without L-R shunts (N = 21), and healthy volunt…

medicine.medical_specialtyeducation.field_of_studyImaging biomarkerReceiver operating characteristicmedicine.diagnostic_testbusiness.industryPopulationMagnetic resonance imagingOxygenationCardiac magnetic resonance imagingInternal medicineCardiologyMedicineRadiology Nuclear Medicine and imagingStage (cooking)businesseducationShunt (electrical)Journal of Magnetic Resonance Imaging
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Revised recommendations of the Italian Society of Pediatrics about the general management of Kawasaki disease

2021

AbstractAim of these revised recommendations for the general management of Kawasaki disease is to encourage its prompter recognition and warrant the most appropriate therapy, based on ascertained scientific data, raising awareness of the complications related to misdiagnosis or delayed treatment. A set of 20 synthetic operative statements is herein provided, including the definition of Kawasaki disease, its protean presentations, clinical course and seminal treatment modalities of all disease phases. The application of these recommendations should improve prognosis of Kawasaki disease and prevent the progression to permanent vascular abnormalities, thereby diminishing morbidity and mortalit…

Pediatricsmedicine.medical_specialty2019-20 coronavirus outbreakAspirin; Children; Coronary artery abnormalities; Intravenous immunoglobulin; Kawasaki diseaseReview030204 cardiovascular system & hematologyMucocutaneous Lymph Node SyndromeDiagnosis Differential03 medical and health sciences0302 clinical medicine030225 pediatricshemic and lymphatic diseasesmedicineHumansChildCoronary artery abnormalitieChildrenIntravenous immunoglobulinAspirinAspirinKawasaki diseasebusiness.industryClinical courselcsh:RJ1-570Immunoglobulins Intravenouslcsh:PediatricsGeneral MedicineDelayed treatmentmedicine.diseasePrognosisSettore MED/38Disease phasesSettore MED/38 - PEDIATRIA GENERALE E SPECIALISTICAEl NiñoItalyTreatment modalityDisease ProgressionAspirin Children Coronary artery abnormalities Intravenous immunoglobulin Kawasaki diseaseKawasaki diseasebusinessCoronary artery abnormalitiesmedicine.drug
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Cardiac imaging in congenital heart disease during the coronavirus disease-2019 pandemic: Recommendations from the Working Group on Congenital Heart …

2020

: The recent outbreak of 2019 severe acute respiratory syndrome coronavirus-2 is having major repercussions on healthcare services provision in Italy and worldwide. Data suggest the virus has a strong impact on the cardiovascular system, and cardiac imaging will play an important role in patients affected by coronavirus disease-2019. Although paediatric patients are mildly affected, they represent a clear accelerator in spreading the virus, and healthcare workers are at higher risk of infection. The aim of this position paper is to provide clinical recommendation regarding the execution of imaging investigations for the cardiac diagnostic work-up of paediatric patients with suspected or con…

Heart diseaseClinical Practice Recommendations and Position Papersevere acute respiratory syndrome coronavirus-2030204 cardiovascular system & hematologymedicine.disease_causePediatricsCongenital0302 clinical medicinePandemicMedicineInfection controlViral030212 general & internal medicineChildSocieties MedicalHeart DefectsCoronavirusPediatricRisk of infectionInfectiousGeneral Medicinecongenital heart diseaseItalyCardiology and Cardiovascular MedicineCoronavirus InfectionsHumanHeart Defects Congenitalmedicine.medical_specialtyPneumonia ViralCardiologycardiac imaging03 medical and health sciencesBetacoronavirusDisease TransmissionMedicalOccupational ExposureDisease Transmission InfectiousHumanscardiac imaging; congenital heart disease; coronavirus disease-2019; severe acute respiratory syndrome coronavirus-2; Betacoronavirus; COVID-19; Cardiac Imaging Techniques; Child; Disease Transmission Infectious; Humans; Infection Control; Italy; Occupational Exposure; SARS-CoV-2; Societies Medical; Cardiology; Coronavirus Infections; Heart Defects Congenital; Pandemics; Pediatrics; Pneumonia ViralIntensive care medicinePandemicsCardiac Imaging TechniqueInfection ControlBetacoronaviruPandemicbusiness.industrySARS-CoV-2Coronavirus Infectioncoronavirus disease-2019OutbreakCOVID-19Pneumoniamedicine.diseasePneumoniaCardiac Imaging TechniquesDisease Transmission InfectiouCardiac Imaging TechniquesSocietiesbusiness
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