0000000000497523

AUTHOR

Benjamin Lebwohl

showing 3 related works from this author

The Risk of Contracting COVID-19 Is Not Increased in Patients With Celiac Disease

2021

The World Health Organization declared coronavirus disease-2019 (COVID-19) a global pandemic in March 2020. Since then, there are more than 34 million cases of COVID-19 leading to more than 1 million deaths worldwide. Numerous studies suggest that celiac disease (CeD), a chronic immune-mediated gastrointestinal condition triggered by gluten, is associated with an increased risk of respiratory infections.(1-3) However, how it relates to the risk of COVID-19 is unknown. To address this gap, we conducted a cross-sectional study to evaluate whether patients with self-reported CeD are at an increased risk of contracting COVID-19.

AdultMalePediatricsmedicine.medical_specialtySettore MED/09 - Medicina InternaCoronavirus disease 2019 (COVID-19)coronavirusDiseasemedicine.disease_causeArticle03 medical and health sciencesDiet Gluten-Free0302 clinical medicineRisk FactorsSurveys and QuestionnairesPandemicOdds RatioMedicineHumansIn patientCoronavirusriskHepatologybusiness.industrySARS-CoV-2Case-control studyGastroenterologyCOVID-19Odds ratioinfectionCeliac Disease030220 oncology & carcinogenesisCase-Control Studiesgluten030211 gastroenterology & hepatologyGluten freeFemalebusiness
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Accuracy of a no-biopsy approach for the diagnosis of coeliac disease across different adult cohorts

2020

ObjectiveWe aimed to determine the predictive capacity and diagnostic yield of a 10-fold increase in serum IgA antitissue transglutaminase (tTG) antibody levels for detecting small intestinal injury diagnostic of coeliac disease (CD) in adult patients.DesignThe study comprised three adult cohorts. Cohort 1: 740 patients assessed in the specialist CD clinic at a UK centre; cohort 2: 532 patients with low suspicion for CD referred for upper GI endoscopy at a UK centre; cohort 3: 145 patients with raised tTG titres from multiple international sites. Marsh 3 histology was used as a reference standard against which we determined the performance characteristics of an IgA tTG titre of ≥10×ULN for …

AdultMalemedicine.medical_specialty2312AdolescentTissue transglutaminaseSerum igaGastroenterologySensitivity and SpecificityCoeliac diseaseEndoscopy GastrointestinalDiagnosis DifferentialPredictive Value of TestsInternal medicineBiopsyMedicineHumans1506Transglutaminasesbiologymedicine.diagnostic_testbusiness.industryGastroenterologyHistologyMiddle Agedmedicine.diseaseUpper GI endoscopyUnited KingdomImmunoglobulin ATiterCeliac DiseaseCohortbiology.proteinbusinessBiomarkerscoeliac disease
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Risk perception and knowledge of COVID-19 in patients with celiac disease

2021

BACKGROUND We recently demonstrated that the odds of contracting coronavirus disease 2019 (COVID-19) in patients with celiac disease (CeD) is similar to that of the general population. However, how patients with CeD perceive their COVID-19 risk may differ from their actual risk. AIM To investigate risk perceptions of contracting COVID-19 in patients with CeD and determine the factors that may influence their perception. METHODS We distributed a survey throughout 10 countries between March and June 2020 and collected data on demographics, diet, COVID-19 testing, and risk perceptions of COVID-19 in patients with CeD. Participants were recruited through various celiac associations, clinic visi…

RiskMalemedicine.medical_specialtyPopulationObservational StudyDiseaseLogistic regressionOdds03 medical and health sciences0302 clinical medicineCOVID-19 TestingCeliac diseaseMedicineHumansCOVID-19 Celiac disease Coronavirus Gluten Infection Knowledge Perception RiskeducationAgededucation.field_of_studyCOVID-19; Celiac disease; Coronavirus; Gluten; Infection; Knowledge; Perception; Risk; Aged; COVID-19 Testing; Humans; Male; Perception; SARS-CoV-2; COVID-19; Celiac Diseasebusiness.industrySARS-CoV-2Public healthfungiGastroenterologyCOVID-19General MedicineOdds ratioMental healthRisk perceptionCoronavirusCeliac DiseaseKnowledge030220 oncology & carcinogenesis030211 gastroenterology & hepatologyPerceptionbusinessInfectionGlutenDemography
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