0000000000502447

AUTHOR

Mariavaleria Pellicano'

Studio longitudinale degli effetti della psicoterapia sulla funzionalità immunitaria in soggetti affetti da disturbo depressivo unipolare

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TRafficking profile in naive and memory B cells in young and old subjects

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Toxic effects induced by recombinant Ab 42 Peptide

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The sea urchin embryo: a model to study Alzheimer's Disease

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Biomarkers of aging

Aging is a complex process that negatively impacts the development of the different systems and its ability to function. Moreover, the Aging rate in humans is not the same, principally due to genetic heterogeneity and environmental factors. The aging rate is measured as the decline of functional capacity and stress resistance. Therefore, several attempts have been made to analyse the individual age, ( so-called biological age) compared to chronological age. The biomarkers of aging are age-related body function or composition, these markers aim to assess the biological age and predict the onset of age-related diseases and/or residual lifetime. Such biomarkers should help in one hand to chara…

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Toxic effects of recombinant b-amyloid prefibrillar oligomers on different model systems

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Sottopopolazioni linfocitarie in soggetti affetti da disturbo depressivo unipolare

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Immune-inflammatory responses in successful and unsuccessful ageing

A dramatic increase in mean life span and life expectancy, coupled with a significant reduction in early mortality, has lead to a large increase in number of elderly people in modern societies. This demographic phenomenon has been paralleled by an epidemic of chronic diseases associated with advancing age. Both innate and instructive immunity are implicated in almost all age-related diseases. The modifications of the immune system in the elderly are evaluated as a deterioration of the immune system, the so-called immunosenescence, which is thought to be mostly the result of the declining effectiveness of T cells and it is responsible for the increased susceptibility of elderly to infectious…

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In vitro reactivity of peripheral blood mononuclear cells from subjects with different genetic background to amyloid b (Ab42) peptide: implication for cancer an immunotherapy.

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