0000000000508738

AUTHOR

Maria Dolores Chirlaque

showing 4 related works from this author

Erratum to "The histology of ovarian cancer: Worldwide distribution and implications for international survival comparisons (CONCORD-2)" [Gynecol. On…

2017

Objective. Ovarian cancers comprise several histologically distinct tumour groups with widely different prognosis. We aimed to describe the worldwide distribution of ovarian cancer histology and to understand what role this may play in international variation in survival. Methods. The CONCORD programme is the largest population-based study of global trends in cancer survival. Data on 681,759 women diagnosed during 1995–2009 with cancer of the ovary, fallopian tube, peritoneum and retroperitonum in 51 countries were included.We categorised ovarian tumours into six histological groups, and explored the worldwide distribution of histology. Results. During 2005–2009, type II epithelial tumours …

Gynecologymedicine.medical_specialty030219 obstetrics & reproductive medicinebusiness.industryPublished ErratumObstetrics and GynecologyLibrary scienceArticle03 medical and health sciences0302 clinical medicineOncologyOvarian cancerEditorial team030220 oncology & carcinogenesisMedicineepidemiologybusinessGynecologic oncology
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Analysis of Heritability and Shared Heritability Based on Genome-Wide Association Studies for Thirteen Cancer Types

2015

BACKGROUND: Studies of related individuals have consistently demonstrated notable familial aggregation of cancer. We aim to estimate the heritability and genetic correlation attributable to the additive effects of common single-nucleotide polymorphisms (SNPs) for cancer at 13 anatomical sites.METHODS: Between 2007 and 2014, the US National Cancer Institute has generated data from genome-wide association studies (GWAS) for 49 492 cancer case patients and 34 131 control patients. We apply novel mixed model methodology (GCTA) to this GWAS data to estimate the heritability of individual cancers, as well as the proportion of heritability attributable to cigarette smoking in smoking-related cance…

MaleCancer ResearchLung NeoplasmsLymphomaGenome-wide association studyPolymorphism (computer science)NeoplasmsMedicineChronicGeneticsOsteosarcomaOncology And CarcinogenesisLeukemiaSmokingFamily aggregationSingle NucleotideMiddle AgedFamilial riskDiffuseKidney NeoplasmsLymphocyticOncologyAdult; Aged; Asian Continental Ancestry Group; Bone Neoplasms; European Continental Ancestry Group; Female; Humans; Kidney Neoplasms; Leukemia Lymphocytic Chronic B-Cell; Lung Neoplasms; Lymphoma Large B-Cell Diffuse; Male; Middle Aged; Neoplasms; Osteosarcoma; Polymorphism Single Nucleotide; Smoking; Testicular Neoplasms; Tissue Array Analysis; Urinary Bladder Neoplasms; Genetic Predisposition to Disease; Genome-Wide Association StudyFemaleLymphoma Large B-Cell DiffuseAdultAsian Continental Ancestry GroupEuropean Continental Ancestry Group/Bone NeoplasmsPolymorphism Single NucleotideGenetic correlationTesticular NeoplasmsLarge B-CellHumansGenetic Predisposition to DiseaseOncology & CarcinogenesisPolymorphismAgedbusiness.industryExtramuralB-CellCancerHeritabilityGenome-wide association studies for thirteen cancer typesmedicine.diseaseLeukemia Lymphocytic Chronic B-CellUrinary Bladder NeoplasmsTissue Array AnalysisbusinessGenome-Wide Association StudyJournal of the National Cancer Institute
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The histology of ovarian cancer: worldwide distribution and implications for international survival comparisons (CONCORD-2).

2016

OBJECTIVE: Ovarian cancers comprise several histologically distinct tumour groups with widely different prognosis. We aimed to describe the worldwide distribution of ovarian cancer histology and to understand what role this may play in international variation in survival. METHODS: The CONCORD programme is the largest population-based study of global trends in cancer survival. Data on 681,759 women diagnosed during 1995-2009 with cancer of the ovary, fallopian tube, peritoneum and retroperitonum in 51 countries were included. We categorised ovarian tumours into six histological groups, and explored the worldwide distribution of histology. RESULTS: During 2005-2009, type II epithelial tumours…

Epidemiology; Histology; Morphology; Ovarain cancer; Worldwide0301 basic medicineOncologyPathologyendocrine system diseasesEpidemiologySex Cord-Gonadal Stromal TumorsCarcinoma Ovarian Epithelial0302 clinical medicineNeoplasmsEpidemiologyNeoplasms Glandular and EpithelialOvarian Neoplasmseducation.field_of_studyEpidemiology; Histology; Morphology; Ovarain cancer; Worldwide; Adolescent; Adult; Aged; Female; Humans; Middle Aged; Neoplasms Germ Cell and Embryonal; Neoplasms Glandular and Epithelial; Ovarian Neoplasms; Sex Cord-Gonadal Stromal Tumors; Oncology; Obstetrics and GynecologyGlandular and EpithelialObstetrics and GynecologyMiddle AgedNeoplasms Germ Cell and Embryonalfemale genital diseases and pregnancy complicationsTransitional cell carcinomaOncology030220 oncology & carcinogenesisClear cell carcinomaFemaleWorldwideHumanMorphologyAdultendocrine systemmedicine.medical_specialtyHistologyAdolescentEpidemiology ; Histology ; Morphology ; Ovarain cancer ; WorldwidePopulationSocio-culturale03 medical and health sciencesInternal medicinemedicineHumansSex Cord-Gonadal Stromal TumorseducationAgedMixed tumorbusiness.industryOvarian NeoplasmSex Cord-Gonadal Stromal TumorHistologymedicine.diseaseOvarain cancerEpidemiology; Histology; Morphology; Ovarain cancer; Worldwide;030104 developmental biologyGerm Cell and EmbryonalOvarian cancerbusinessGynecologic oncology
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Erratum to “Worldwide comparison of ovarian cancer survival: Histological group and stage at diagnosis (CONCORD-2)” [Gynecol. Oncol. 144 (2017) 396–4…

2017

Objective. Ovarian cancer comprises several histological groups with widely differing levels of survival. We aimed to explore international variation in survival for each group to help interpret international differences in survival from all ovarian cancers combined. We also examined differences in stage-specific survival. Methods. The CONCORD programme is the largest population-based study of global trends in cancer survival, including data from 60 countries for 695,932 women (aged 15–99 years) diagnosed with ovarian cancer during 1995–2009. We defined six histological groups: type I epithelial, type II epithelial, germ cell, sex cord-stromal, other specific non-epithelial and non-specific…

0301 basic medicineGynecologymedicine.medical_specialtybusiness.industryPublished ErratumObstetrics and GynecologyLibrary scienceSettore MED/42 - Igiene Generale E Applicata03 medical and health sciences030104 developmental biology0302 clinical medicineOncologyEditorial team030220 oncology & carcinogenesismedicinebusinessStage at diagnosisGynecologic Oncology
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