6533b822fe1ef96bd127cc71
RESEARCH PRODUCT
The histology of ovarian cancer: worldwide distribution and implications for international survival comparisons (CONCORD-2).
Melissa MatzMichel ColemanMilena SantMaria Dolores ChirlaqueOtto VisserMartin GoreClaudia AllemaniS BouzbidM Hamdi-chérifZ ZaidiE BahR SwaminathanSh NortjeMm El MistiriS BayoB MalleSs ManrajR Sewpaul-sungkurA FabowaleOj OgunbiyiD BradshawNim SomdyalaDc StefanM Abdel-rahmanL JaidaneM MokniI KumcherF MorenoMs GonzálezEa LauraSb EspinolaGh CalabranoB Carballo QuinteroR FitaDa GarcilazoPl GiaccianiMc DiumenjoWd LaspadaMa GreenMf LanzaSg IbañezCa LimaE Lobo De OliveiraC DanielC ScandiuzziPcf De SouzaCd MeloK Del PinoC LaporteMp CuradoJc De OliveiraCla VenezianoDb VenezianoMrdo LatorreLf TanakaG Azevedo E. SilvaJc GalazJa MoyaDa HerrmannS VargasVm HerreraCj UribeLe BravoNe Arias-ortizDm JuradoMc YépezYh GalánP TorresF Martínez-reyesMl Pérez-mezaL JaramilloR QuintoP CuevaJg YépezCr Torres-cintrónG Tortolero-lunaR AlonsoE BarriosC NikiforukL ShackAj ColdmanRr WoodsG NoonanD TurnerE KumarB ZhangFr MccrateS RyanH HannahRad DewarM MacintyreA LalanyM RutaL MarrettDe NishriC McclureKa VriendsC BertrandR LouchiniK RobbH Stuart-pankoS DemersS WrightJt GeorgeX ShenJt BrockhouseDk O'brienKc WardL AlmonJ BatesR RycroftL MuellerC PhillipsH BrownB CromartieAg SchwartzF VigneauJa MackinnonB WohlerAr BayaklyCa ClarkeSl GlaserD WestMd GreenBy HernandezCj JohnsonD JozwikMe CharltonCf LynchB HuangTc TuckerD DeapenL LiuMc HsiehXc WuK SternSt GershmanRc KnowltonJ AlversonGe CopelandDb RogersD LemonsLl WilliamsonM HoodGm HosainJr ReesKs PawlishA StroupC KeyC WigginsAr KahnMj SchymuraG LeungC RaoL GiljahnB WartherA PateM PatilSs SchubertJj RubertoneSj SlackJp FultonDl RousseauJanesTa: SchwartzSmSw BolickDm HurleyJ RichardsMa WhitesideLm NogueiraK HergetC SweeneyJ MartinS WangDg HarrelsonMb Keitheri CheteriS FarleyAg HudsonR BorchersL StephensonJr EspinozaHk WeirBk EdwardsN WangL YangJs ChenGh SongXp GuP ZhangHm GeDl ZhaoJh ZhangFd ZhuJg TangY ShenJ WangQl LiXp YangJ DongW LiLp ChengJg ChenQh HuangSq HuangGp GuoK WeiWq ChenH ZengAv DemetriouP PavlouWk MangKc NganR SwaminathanAc KatakiM KrishnatreyaPa JayalekshmiP SebastianSd SapkotaY VermaA NandakumarE SuzannaL Keinan-bokerBg SilvermanH ItoH NakagawaM HattoriY KaizakiH SugiyamaM UtadaK KatayamaH NarimatsuS KanemuraT KoikeI MiyashiroM YoshiiI OkiA ShibataT MatsudaO NimriA Ab MananN Bhoo-pathyS TuvshingerelO ChimedsurenAhm Al KhaterMm El MistiriH Al-eidKw JungYj WonCj ChiangMs LaiK SuwanrungruangS WiangnonK DaoprasertD PongnikornSl GeaterH SriplungS EserCi YakutM HacklH MühlböckW OberaignerAa ZborovskayaOv AleinikovaK HenauL Van EyckenN DimitrovaZ ValerianovaM ŠEkerijaM ZvolskýG EngholmH StormK InnosM MägiN MalilaK SeppäJ JéguM VeltenE CornetX TroussardAm BouvierJ FaivreAv GuizardV BouvierG LaunoyP ArveuxM MaynadiéM MounierE FournierAs WoronoffM DaoulasJ ClavelS Le Guyader-peyrouA MonnereauB TrétarreM ColonnaA Cowppli-bonyF MoliniéS BaraD DegréO GanryB Lapôtre-ledouxP GrosclaudeJ EstèveF BrayM PiñerosF SassiR StabenowA EberleC ErbA NenneckeJ KieschkeE SirriH KajueterK EmrichSr ZeissigB HolleczekN EisemannA KatalinicH BrennerRa AsquezV KumarEj ÓLafsdóttirL TryggvadóttirH ComberPm WalshH SundsethE DevigiliG MazzoleniA GiacominFrancesca Di BellaM CastaingA SuteraG GolaS FerrettiD SerrainoA ZucchettoR LilliniM VercelliS BuscoF PannozzoS VitarelliP RicciC PascucciM AutelitanoC CirilliM FedericoElena Maria FuscoMf VitaleM UsalaR CusimanoW MazzuccoM MichiaraP SgargiMm MauleC SacerdoteR TuminoE Di FeliceM VicentiniF FalciniL CremoneM BudroniR CesaraccioMl ContrinoF TisanoAc FanettiS MasperoG CandelaT ScuderiMa GentiliniS PifferS RossoL SacchettoA CaldarellaF La RosaF StracciP ContieroG TagliabueAp Dei TosM ZorziR ZanettiP BailiF BerrinoG GattaM SantR CapocacciaR De AngelisE LiepinaA MaurinaG SmailyteD AgiusN CallejaS SieslingO VisserS LarønningenB MøllerA Dyzmann-srokaM TrojanowskiS GóźdżR MężykM Grądalska-lampartAu RadziszewskaJa DidkowskaU WojciechowskaJ BłaszczykK KępskaM Bielska-lasotaK KwiatkowskaG ForjazRa RegoJ BastosMa SilvaL AntunesMj BentoA Mayer-da-silvaA MirandaD CozaAi TodescuMy ValkovJ AdamcikC Safaei DibaM Primic-žakeljT ŽAgarJ StareE AlmarA MateosJr QuirósJ BidaurrazagaN LarrañagaJm Díaz GarcíaAi MarcosR Marcos-grageraMl Vilardell GilE MolinaMj SánchezP Franch SuredaM Ramos MontserratMd ChirlaqueC NavarroEe ArdanazCc Moreno-iribasR Fernández-delgadoR Peris-bonetJ GalceranS KhanM LambeB CameyC BouchardyM UselSm EssC HerrmannJl BulliardM Maspoli-conconiH FrickCe KuehniM SchindlerA BordoniA SpitaleA ChioleroI KonzelmannSi DehlerKl MatthesJ RashbassCa StillerD FitzpatrickA GavinF BannonRj BlackDh BrewsterDw HuwsC WhiteP FinanC AllemaniA BonaventureH CarreiraMp ColemanV Di CarloR HarewoodK LiuM MatzL MontelM NikšićB RachetN SanzD SpikaR StephensM PeakeE ChalkerL NewmanD BakerMj SoebergJ AitkenC ScottBc StokesA VennH FarrugiaGg GilesT ThrelfallD CurrowH YouJ HendrixC. Lewissubject
Epidemiology; Histology; Morphology; Ovarain cancer; Worldwide0301 basic medicineOncologyPathologyendocrine system diseasesEpidemiologySex Cord-Gonadal Stromal TumorsCarcinoma Ovarian Epithelial0302 clinical medicineNeoplasmsEpidemiologyNeoplasms Glandular and EpithelialOvarian Neoplasmseducation.field_of_studyEpidemiology; Histology; Morphology; Ovarain cancer; Worldwide; Adolescent; Adult; Aged; Female; Humans; Middle Aged; Neoplasms Germ Cell and Embryonal; Neoplasms Glandular and Epithelial; Ovarian Neoplasms; Sex Cord-Gonadal Stromal Tumors; Oncology; Obstetrics and GynecologyGlandular and EpithelialObstetrics and GynecologyMiddle AgedNeoplasms Germ Cell and Embryonalfemale genital diseases and pregnancy complicationsTransitional cell carcinomaOncology030220 oncology & carcinogenesisClear cell carcinomaFemaleWorldwideHumanMorphologyAdultendocrine systemmedicine.medical_specialtyHistologyAdolescentEpidemiology ; Histology ; Morphology ; Ovarain cancer ; WorldwidePopulationSocio-culturale03 medical and health sciencesInternal medicinemedicineHumansSex Cord-Gonadal Stromal TumorseducationAgedMixed tumorbusiness.industryOvarian NeoplasmSex Cord-Gonadal Stromal TumorHistologymedicine.diseaseOvarain cancerEpidemiology; Histology; Morphology; Ovarain cancer; Worldwide;030104 developmental biologyGerm Cell and EmbryonalOvarian cancerbusinessdescription
OBJECTIVE: Ovarian cancers comprise several histologically distinct tumour groups with widely different prognosis. We aimed to describe the worldwide distribution of ovarian cancer histology and to understand what role this may play in international variation in survival. METHODS: The CONCORD programme is the largest population-based study of global trends in cancer survival. Data on 681,759 women diagnosed during 1995-2009 with cancer of the ovary, fallopian tube, peritoneum and retroperitonum in 51 countries were included. We categorised ovarian tumours into six histological groups, and explored the worldwide distribution of histology. RESULTS: During 2005-2009, type II epithelial tumours were the most common. The proportion was much higher in Oceania (73.1%), North America (73.0%) and Europe (72.6%) than in Central and South America (65.7%) and Asia (56.1%). By contrast, type I epithelial tumours were more common in Asia (32.5%), compared with only 19.4% in North America. From 1995 to 2009, the proportion of type II epithelial tumours increased from 68.6% to 71.1%, while the proportion of type I epithelial tumours fell from 23.8% to 21.2%. The proportions of germ cell tumours, sex cord-stromal tumours, other specific non-epithelial tumours and tumours of non-specific morphology all remained stable over time. CONCLUSIONS: The distribution of ovarian cancer histology varies widely worldwide. Type I epithelial, germ cell and sex cord-stromal tumours are generally associated with higher survival than type II tumours, so the proportion of these tumours may influence survival estimates for all ovarian cancers combined. The distribution of histological groups should be considered when comparing survival between countries and regions.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2016-12-06 | Gynecologic oncology |