0000000000513016

AUTHOR

Ana Pérez-heras

showing 5 related works from this author

Legume consumption is inversely associated with type 2 diabetes incidence in adults: A prospective assessment from the PREDIMED study

2018

Background & aims: Legumes, a low-energy, nutrient-dense and low glycemic index food, have shown beneficial effects on glycemic control and adiposity. As such, legumes are widely recommended in diabetic diets, even though there is little evidence that their consumption protects against type 2 diabetes. Therefore the aim of the present study was to examine the associations between consumption of total legumes and specific subtypes, and type 2 diabetes risk. We also investigated the effect of theoretically substituting legumes for other protein- or carbohydrate-rich foods. Methods: Prospective assessment of 3349 participants in the PREvención con DIeta MEDiterránea (PREDIMED) study without ty…

0301 basic medicineGerontologyBlood GlucoseMaleLentilsMediterranean dietPREDIMED-study030209 endocrinology & metabolismContext (language use)Type 2 diabetesCritical Care and Intensive Care MedicineLower riskDiet Mediterranean03 medical and health sciences0302 clinical medicineRisk FactorsDiabetes mellitusmedicineHumansProspective StudiesGlycemicAdiposityAgedProportional Hazards Models030109 nutrition & dieteticsNutrition and Dieteticsbusiness.industryFabaceaeType 2 diabetesMiddle Agedmedicine.diseaseLegumesDietGlycemic indexQuartileDiabetes Mellitus Type 2Glycemic IndexFemalebusinessDemographyFollow-Up Studies
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Effect of a 2-year diet intervention with walnuts on cognitive decline. The Walnuts And Healthy Aging (WAHA) study: a randomized controlled trial

2019

Background Walnut consumption counteracts oxidative stress and inflammation, 2 drivers of cognitive decline. Clinical data concerning effects on cognition are lacking. Objectives The Walnuts And Healthy Aging study is a 2-center (Barcelona, Spain; Loma Linda, CA) randomized controlled trial examining the cognitive effects of a 2-y walnut intervention in cognitively healthy elders. Methods We randomly allocated 708 free-living elders (63-79 y, 68% women) to a diet enriched with walnuts at ∼15% energy (30-60 g/d) or a control diet (abstention from walnuts). We administered a comprehensive neurocognitive test battery at baseline and 2 y. Change in the global cognition composite was the primary…

Malemedicine.medical_specialtyMedicine (miscellaneous)Juglanslaw.inventionHealthy Aging03 medical and health sciences0302 clinical medicineRandomized controlled trialMemorylawInternal medicineIntervention (counseling)medicineHumansNutsCognitive Dysfunction030212 general & internal medicineCognitive declineAgedNutrition and DieteticsIntention-to-treat analysismedicine.diagnostic_testbusiness.industryBrainCognitionNeuropsychological testMiddle AgedMagnetic Resonance ImagingSpainCohortFemalebusinessNeurocognitive030217 neurology & neurosurgeryThe American Journal of Clinical Nutrition
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Mediterranean diet supplemented with nuts reduces waist circumference and shifts lipoprotein subfractions to a less atherogenic pattern in subjects a…

2013

[Objective]: The PREDIMED trial showed that Mediterranean diets supplemented with either extra-virgin olive oil or nuts reduced incident cardiovascular events compared to a control diet. Consumption of both supplemental foods has been associated with reduced LDL-cholesterol, but it is unknown whether they can shift lipoprotein subfractions to a less atherogenic pattern. We investigated changes in adiposity and lipoprotein subfractions after consumption of the PREDIMED diets.

MalePREDIMEDmedicine.medical_specialtyMagnetic Resonance SpectroscopyTime FactorsWaistMediterranean dietLipoproteinsDiet MediterraneanHDL sizeDecreased LDLLDL sizeCohort StudiesRisk FactorsInternal medicinemedicineHumansPlant OilsNutsIncreased ldlParticle SizeSmall-dense LDLTriglyceridesAgedAged 80 and overVLDL sizebusiness.industryfood and beveragesCholesterol LDLMiddle AgedAtherosclerosisCircumferencePredimedLipoproteins LDLEndocrinologyCardiovascular DiseasesFemalelipids (amino acids peptides and proteins)Waist CircumferenceCardiology and Cardiovascular MedicinebusinessOlive oilLipoproteinOlive oil
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Mediterranean Diet and Age-Related Cognitive Decline

2015

IMPORTANCE: Oxidative stress and vascular impairment are believed to partly mediate age-related cognitive decline, a strong risk factor for development of dementia. Epidemiologic studies suggest that a Mediterranean diet, an antioxidant-rich cardioprotective dietary pattern, delays cognitive decline, but clinical trial evidence is lacking. OBJECTIVE: To investigate whether a Mediterranean diet supplemented with antioxidant-rich foods influences cognitive function compared with a control diet. DESIGN, SETTING, AND PARTICIPANTS: Parallel-group randomized clinical trial of 447 cognitively healthy volunteers from Barcelona, Spain (233 women [52.1%]; mean age, 66.9 years), at high cardiovascular…

MaleGerontologyAgingWechsler Memory ScaleMediterranean dietNeuropsychological TestsDiet MediterraneanTrastorns de la cognicióCognitionMediterranean cookingEnvellimentCuina mediterràniaInternal MedicineMemory spanmedicineHumansNeuropsychological assessmentCognitive declineTests neuropsicològicsDieta -- Mediterrània Regió de laAgedAged 80 and overmedicine.diagnostic_testbusiness.industryEnvelliment cerebralWechsler Adult Intelligence ScaleNeuropsychological testMiddle AgedCognitive testAging brainFemaleCognition DisordersbusinessDemographyJAMA Internal Medicine
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Dietary inflammatory index and all-cause mortality in large cohorts: The SUN and PREDIMED studies

2019

[Background]: Inflammation is known to be related to the leading causes of death including cardiovascular disease, several types of cancer, obesity, type 2 diabetes, depression-suicide and other chronic diseases. In the context of whole dietary patterns, the Dietary Inflammatory Index (DII®) was developed to appraise the inflammatory potential of the diet. [Objective]: We prospectively assessed the association between DII scores and all-cause mortality in two large Spanish cohorts and valuated the consistency of findings across these two cohorts and results published based on other cohorts.

AdultMale0301 basic medicinemedicine.medical_specialtyMediterranean diet030209 endocrinology & metabolismContext (language use)Type 2 diabetesDiet MediterraneanCritical Care and Intensive Care MedicineDietary inflammatory indexBody Mass IndexYoung Adult03 medical and health sciences0302 clinical medicineRisk FactorsInternal medicineMediterranean dietHumansMedicineObesityProspective StudiesMortalityProspective cohort studyRandomized Controlled Trials as TopicInflammation030109 nutrition & dieteticsNutrition and Dieteticsbusiness.industrySmokingHazard ratioMiddle Agedmedicine.diseaseObesityDietC-Reactive ProteinDiabetes Mellitus Type 2CohortPatient ComplianceCohort studiesFemalebusinessCRPCohort study
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