0000000000514323
AUTHOR
G. Alfieri
showing 3 related works from this author
Real-life impact of early interferon beta therapy in relapsing multiple sclerosis.
2009
OBJECTIVE: Recent findings support greater efficacy of early vs. delayed interferon beta (IFNbeta) treatment in patients with a first clinical event suggestive of multiple sclerosis (MS). We aimed to evaluate the effectiveness of early IFNbeta treatment in definite relapsing-remitting MS (RRMS) and to assess the optimal time to initiate IFNbeta treatment with regard to the greatest benefits on disability progression. METHODS: A cohort of 2,570 IFNbeta-treated RRMS patients was prospectively followed for up to 7 years in 15 Italian MS Centers. A Cox proportional hazards regression model adjusted for propensity score (PS) quintiles was used to assess differences between groups of patients wit…
Fine-scale spatial variability of soil organic carbon and related environmental variables in a protected area of Sicily, Italy
2008
The institution of Natural Reserves has promoted, in Italy, the conservation and the environmental improvement of several areas and their physical and biological factors. Agriculture, forestry and every human activity are regulated to preserve their high ecological and naturalistic value. Land use, in particular, must follow careful rules to preserve the soil fertility and to limit the factors of landscape degradation. Maps of soil organic carbon (SOC) or soil organic matter (SOM) are of interest for agricultural management, resulting a very important soil fertility parameter, as well as in environmental policy related to the terrestrial sequestration of atmospheric carbon. Thus, a better u…
Vascular risk factors in glaucoma: The results of a national survey
2007
Background The role of vascular risk factors in glaucoma is still being debated. To assess the importance of vascular risk factors in patients with primary open-angle glaucoma (POAG), data from the medical history of 2,879 POAG patients and 973 age-matched controls were collected and analyzed. Methods Design: observational survey. Setting: 35 Italian academic centers. Study population: POAG patients and age-matched controls. In order to reduce bias consecutive patients were included. Observation procedures: data concerning vascular risk factors were collected for all patients with a detailed questionnaire. A complete ophthalmological examination with assessment of intraocular pressure (IOP)…