0000000000515255
AUTHOR
J. Benitez-del-castillo Sánchez
showing 2 related works from this author
Determinación de mediadores de la respuesta inmune e inflamación en lágrimas: cambios en ojo seco y glaucoma frente a población sana
2017
Resumen Objetivo Determinar el perfil de expresion de las moleculas mediadoras de inflamacion y respuesta inmune (IRI) en lagrimas de pacientes con ojo seco (OS) y pacientes en tratamiento medico por sospecha o diagnostico de glaucoma primario de angulo abierto (GPAA) para compararlos con sujetos sanos. Metodo Estudio prospectivo observacional de cohortes de 107 participantes subdivididos en: pacientes con OS (GOS; n = 30), pacientes con sospecha o diagnostico de GPAA con tratamiento hipotensor ocular (GGPAA; n = 41) y controles sanos (GC; n = 36). Se obtuvieron muestras de lagrimas mediante capilaridad para analizarlas mediante sistema de multiinmunoanalisis basado en citometria de flujo (…
Determination of inmune response and inflammation mediators in tears: Changes in dry eye and glaucoma as compared to healthy controls
2017
Objective To determine the expression profile of immune response and inflammation (IRI) mediator molecules in tears from patients with dry eye (DE), and those suspected of having or have primary open-angle glaucoma (POAG) under treatment and compare them with healthy controls. Methods A prospective observational cohort study including 107 participants sub-divided into: healthy controls (CG; n = 30), patients with DE (DEG; n = 41) and patients suspected of having or have POAG and on hypotensive treatment (POAG-G; n = 36). Tear samples were collected by capillary to be processed using a multi-immunoassay system based on flow cytometry (Luminex R-200®), in order to determine the interleukins (…