0000000000515281

AUTHOR

Ahmed M. El-sharkawy

showing 2 related works from this author

LP24 : Safety, efficacy and impact on liver function of simeprevir (SMV) in combination with daclatasvir (DCV) or sofosbuvir (SOF) in patients with s…

2015

Simeprevirmedicine.medical_specialtyDaclatasvirHepatologySofosbuvirbusiness.industrymedicine.medical_treatmentCompassionate UseLiver transplantationGastroenterologyHepatitis a virusSurgeryInternal medicinemedicineIn patientLiver functionbusinessmedicine.drugJournal of Hepatology
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The Impact of Direct-acting Antivirals on Overall Mortality and Tumoral Recurrence in Patients With Hepatocellular Carcinoma Listed for Liver Transpl…

2020

BACKGROUND There is a lack of data on the use of direct-acting antivirals (DAA) on the risk of death and tumoral recurrence in patients with hepatitis C virus (HCV) and hepatocellular carcinoma (HCC) listed for liver transplantation (LT). We aimed to assess the impact of antiviral treatment on mortality and HCC recurrence patients with HCC-HCV. METHODS This was a retrospective multicenter study of patients with HCC-HCV listed for LT from 2005 to 2015. Patients were divided according to the antiviral treatment received after HCC diagnosis: DAA, interferon (IFN), or no antiviral. Intention-to-treat overall survival and HCC recurrence incidence were compared by the Kaplan-Meier method. Multiva…

Malemedicine.medical_specialtyCarcinoma HepatocellularTime FactorsWaiting Listsmedicine.medical_treatment030230 surgeryLiver transplantationGastroenterologyAntiviral AgentsRisk Assessment03 medical and health sciences0302 clinical medicineInterquartile rangeRisk FactorsInternal medicineCarcinomamedicineHumansRisk factorRetrospective StudiesTransplantationbusiness.industryIncidence (epidemiology)Hazard ratioLiver NeoplasmsRetrospective cohort studyMiddle Agedmedicine.diseaseHepatitis Cdigestive system diseasesLiver TransplantationTreatment OutcomeHepatocellular carcinoma030211 gastroenterology & hepatologyFemaleNeoplasm Recurrence LocalbusinessTransplantation
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