0000000000517018

AUTHOR

Michael Koller

showing 3 related works from this author

Psychometric properties of the updated EORTC module for assessing quality of life in patients with lung cancer (QLQ-LC29): an international, observat…

2020

Abstract: Background The European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire-Lung Cancer 13 (QLQ-LC13) assesses quality of life (QOL) in patients with lung cancer and was the first EORTC module developed for use in international clinical trials. Since its publication in 1994, major treatment advances with possible effects on QOL have occurred. These changes called for an update of the module and its international psychometric validation. We aimed to investigate the scale structure and psychometric properties of the updated lung cancer module, QLQ-LC29, in patients with lung cancer. Methods This international, observational field study was done in…

Malemedicine.medical_specialtyPsychometricsPsychometrics10255 Clinic for Thoracic SurgeryQUESTIONNAIRE610 Medicine & health03 medical and health sciences0302 clinical medicineCronbach's alphaQuality of lifeCarcinoma Non-Small-Cell LungSurveys and QuestionnairesMedicine and Health SciencesmedicineHumans030212 general & internal medicineVALIDITYLung cancerAgedLanguagebusiness.industryQLQ-C30CancerMiddle Agedmedicine.diseaseSmall Cell Lung CarcinomaTRENDShumanitiesConfirmatory factor analysisClinical trialOncology030220 oncology & carcinogenesisQuality of LifePhysical therapyFemaleObservational study2730 OncologyHuman medicinebusinessCLINICAL-TRIALS
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Problem solving strategies with biomedical and clinimetric components: The case of perioperative H1-+H2-prophylaxis

1992

A formal (objective) problem solving strategy was developed for the question whether a perioperative histamine H1-+H2-prophylaxis should be applied to patients at risk for a histamine release reaction or for a special severity of such a reaction even in the case of a minor histamine release.

Pharmacologymedicine.medical_specialtybusiness.industryImmunologyPharmacology toxicologyPerioperativeToxicologyRheumatologychemistry.chemical_compoundchemistryInternal medicineAnesthesiaMedicinePharmacology (medical)businessIntensive care medicineHistamineAgents and Actions
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Methodological aspects of clinical trials in tinnitus: a proposal for an international standard

2012

Abstract: Chronic tinnitus is a common condition with a high burden of disease. While many different treatments are used in clinical practice, the evidence for the efficacy of these treatments is low and the variance of treatment response between individuals is high. This is most likely due to the great heterogeneity of tinnitus with respect to clinical features as well as underlying pathophysiological mechanisms. There is a clear need to find effective treatment options in tinnitus, however, clinical trials differ substantially with respect to methodological quality and design. Consequently, the conclusions that can be derived from these studies are limited and jeopardize comparison betwee…

Research designmedicine.medical_specialtyAlternative medicineMEDLINE610 Medicine & health10045 Clinic for OtorhinolaryngologyArticleTinnitus2738 Psychiatry and Mental Healthotorhinolaryngologic diseasesMedicineHumansClinical Trials as TopicEvidence-Based Medicinebusiness.industry3203 Clinical PsychologyVariance (accounting)Evidence-based medicineGuidelineClinical trialPsychiatry and Mental healthClinical PsychologyResearch DesignHuman medicinemedicine.symptombusinessTinnitusClinical psychology
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