0000000000519365

AUTHOR

Pozo-kreilinger Jj

showing 1 related works from this author

Bisphosphonate-related osteonecrosis. Application of adipose-derived stem cells in an experimental murine model

2019

Background Bisphosphonate-related osteonecrosis of the jaw is a pathological condition without effective established treatment and preventive strategies. The aim of this study was to analyse the effect of adipose-derived stem cells (ASC) in an experimental murine model of osteonecrosis. Material and Methods 38 Wistar rats were injected intraperitoneally with zoledronic acid. After treatment, upper jaw molars were extracted. The animals were randomly assigned to one of two groups. In the control group, saline solution was applied over the alveolar sockets after the tooth extractions. In the treatment group, ASCs were applied instead of saline solution. The control and treatment groups were s…

Pathologymedicine.medical_specialtymedicine.medical_treatmentReviewBone remodelingMice03 medical and health sciences0302 clinical medicinemedicineAnimalsRats WistarGeneral DentistryDental alveolusBisphosphonate-associated osteonecrosis of the jawBone Density Conservation AgentsDiphosphonatesbusiness.industryStem CellsImidazolesOsteonecrosis030206 dentistryBisphosphonate:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseRatsDisease Models AnimalBone Density Conservation AgentsZoledronic acidOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASTooth ExtractionBisphosphonate-Associated Osteonecrosis of the JawSurgeryOral SurgeryStem cellbusinessOsteonecrosis of the jawmedicine.drugMedicina Oral Patología Oral y Cirugia Bucal
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