0000000000527111
AUTHOR
L Giordano
showing 7 related works from this author
Randomized double-blind placebo-controlled trial of acetyl-L-carnitine for ALS.
2013
Our objective was to assess the effects of acetyl-L-carnitine (ALC) with riluzole on disability and mortality of amyotrophic lateral sclerosis (ALS). Definite/probable ALS patients, 40-70 years of age, duration 6-24 months, self-sufficient (i.e. able to swallow, cut food/handle utensils, and walk), and with forced vital capacity (FVC) > 80% entered a pilot double-blind, placebo-controlled, parallel group trial and were followed for 48 weeks. ALC or placebo 3 g/day was added to riluzole 100 mg/day. Primary endpoint: number of patients no longer self-sufficient. Secondary endpoints: changes in ALSFRS-R, MRC, FVC and McGill Quality of Life (QoL) scores. Analysis was made in the intention-to-tr…
Il monumento funerario del Doge Marino Grimani a San Giuseppe di Castello
2003
Final Report of the Oceanographic Survey NextData201. Project NEXTDATA WP-1.5 : Paleoclimatic Data from Marine Sediments
2013
The retrieval of series of proxy data on the past climate will serve to acquire a deeper understanding of the climate system and a more accurate prediction of its future development, as a priority task for the scientific community. In particular, the analysis of climate data of the past is an essential tool for studying the dynamics of the earth's climatic system in conditions different from present ones, and irreplaceable for testing the validity of medium- and long-term forecasting models. The determination of the influence of anthropogenic impacts on the planet’s environment is predicated on a clear understanding of the natural ways in which the earth's climate responds to the complex se…