0000000000527233
AUTHOR
La Grutta S
Paracetamol and antibiotics in childhood and subsequent development of wheezing/asthma: association or causation?
Background Several studies found an association between early administration of paracetamol and antibiotics and development of wheezing. This could be due to confounding: wheeze and asthmatic symptoms in early childhood are difficult to distinguish from respiratory tract infections that are widely treated with these drugs; in case of persistence of symptoms up to school age, this could explain the observed relationship. Methods We investigated the association between paracetamol and antibiotics use in the first year of life and wheezing phenotypes, i.e. wheezing starting in different time periods (early, persistent and late-onset) in the SIDRIA-2 study, a cross-sectional survey of 16,933 ch…
Gruppo, traumi collettivi, resilienza, riparazione
i traumi collettivi inducono angoscia e gli effetti drammatici sul singolo e sulla comunità variano lungo un continuum di gravità. in tal senso la riparazione, atta a preservare gli oggetti buoni dalla disintegrazione degli attacchi distruttivi
Congenital adrenal hypoplasia and hearing loss. A case report
We report on the diagnostics, the therapeutics and the follow-up (to 3 years and 5 months) of a newborn affected by X-linked congenital adrenal hypoplasia. After the beginning of substitute hormonal therapy, the patient underwent periodical clinical examinations, with particular attention to the growth, and laboratory tests, which monitored the hormonal pattern. This experience points out the diagnostic role of low maternal levels of urinary estriol during pregnancy and the importance of a prolonged follow-up, so as to discover associated pathologies as early as possible. In our case, in fact, the study of auditory brainstem responses enabled us to recognize a mild transmission hearing loss…
Application of latent class analysis in assessing the awareness, attitude, practice and satisfaction of paediatricians on sleep disorder management in children in Italy
Aim To identify subgroups regarding paediatricians’ awareness, attitude, practice and satisfaction about management of Sleep-Disordered Breathing (SDB) in Italy using Latent Class Analysis (LCA). Methods A cross-sectional study was conducted on a large sample of Italian paediatricians. Using a self-administered questionnaire, the study collected information on 420 Paediatric Hospital Paediatricians (PHPs) and 594 Family Care Paediatricians (FCPs). LCA was used to discover underlying response patterns, thus allowing identification of respondent groups with similar awareness, attitude, practice and satisfaction. A logistic regression model was used to investigate which independent variables i…
Pollen-induced allergic rhinitis in 1360 Italian children: comorbidities and determinants of severity
BACKGROUND: Pollen-induced allergic rhinoconjunctivitis (AR) is highly prevalent and rapidly evolving during childhood. General practitioners may not be fully aware of the nature and severity of symptoms experienced by patients and might underestimate the prevalence of moderate or severe disease. Thus, the relevance of early diagnosis and intervention may be overlooked. OBJECTIVES: To investigate the severity of pollen-induced AR and its determinants in Italian children referred to allergy specialists and who had never received specific immunotherapy (SIT). METHODS: Children (age 4-18 yr) affected by pollen-induced AR who had never undergone SIT were recruited between May 2009 and June 2011…
La spirometria nel bambino collaborante
La spirometria fornisce al medico l’opportunità di accertare la normalità ed il grado di anomalia della funzione respiratoria. Oggi è disponibile una grande varietà di attrezzature computerizzate per l’esecuzione della spirometria in età pediatrica e, in particolare, gli apparecchi che si basano sulla misura del flusso mediante pneumotacografo o turbina sono di facile uso ambulatoriale. I principali parametri misurati sono: FVC, FEV1, PEF, FEF25-75 ed il rapporto FEV1/FVC %. Attraverso l’esame spirometrico è possibile identificare almeno 3 pattern di condizione respiratoria patologica: 1) la disfunzione ventilatoria di tipo ostruttivo; 2) la disfunzione ventilatoria di tipo restrittivo; 3) …
Specific recommendations for PROs and HRQoL assessment in allergic rhinitis and/or asthma: a GA(2)LEN taskforce position paper
The GA(2)LEN taskforce on Patient-Reported Outcomes (PROs) and Health-Related Quality of Life (HRQoL) published in 2009 a position paper concerning PROS and HRQoL assessment in clinical trials on allergy. Because of the specificity of this topic in asthma and rhinitis, specific recommendations are needed. The aim of this position paper is to define PROs and their meaning in asthma and rhinitis research, explore the available tools to provide criteria for a proper choice, identify patient-related factor which could influence PROs assessment, define specific recommendations for assessment, analysis and results spreading, underline the unexplored areas and unmet needs. PROs assessment is gaini…
Predictive signs and indicators of aggressiveness and violence: a comparison between a group of adolescents attending an external penal area, a group of prisoners and a group of patients with borderline personality disorder
Aim. We considered the spreading and the increasing of aggressive and violent behaviours. The most of them have two common roots: lack of actual motivation and brutality. Our research intends to detect specific indicators and predictive signs of violent and aggressive behaviours. In order to this, scientific literature shows that the most reliable indicators and predictive signs are linked to structural personality features (e.g. defensive strategies, impulse control). Methods. This cross sectional study compares a group of 26 male adolescents with Conduct Disorder (F91.8), a group of 29 male patients with Borderline Personality Disorder (F60.31) and a group of 33 male prisoners with Antiso…
Wheeze and asthma in children: associations with body mass index, sports, television viewing, and diet.
Obesity, physical activity, and dietary habits are distinct but strongly interrelated lifestyle factors that may be relevant to the prevalence of wheeze and asthma in children. Our goal was to analyze the relationship of body mass index (BMI), regular sports participation, TV viewing, and diet with current wheezing and asthma.We investigated 20,016 children, aged 6-7 years, who were enrolled in a population-based study. Parents completed standardized questionnaires. Logistic regression was used to estimate odds ratios (ORs) and 95% confidence intervals (CIs), while adjusting for several confounders and simultaneously considering BMI, regular sports activity, TV viewing and selected dietary …
DIFFERENCES BETWEEN CHILDREN'S SELF-PERCEIVED AND TEACHER RATINGS IN TRAIT EMOTIONAL INTELLIGENCE AND ANXIETY: IS THERE A RELATIONSHIP WITH SCHOLASTIC RESULTS IN PRIMARY SCHOOL CHILDREN?
The construct of Emotional Intelligence (EI) has been studied as a potential predictor of psychological wellbeing and social interaction during childhood. Among the different possible EI formulations, some studies about Trait EI during development have also focused on its relationship with academic performance. One main limitation pertains the self-report nature of trait EI assessment tools. The use of cross-informant ratings has become an important aspect of research and clinical practice for those working with children and adolescents because potentially resulting in a less biased approach in the evaluation process. The present study is a cross informant design which involved 150 children…
EXPLORING THE RELATIONSHIP BETWEEN TRAIT EMOTIONAL INTELLIGENCE, ANXIETY AND DEPRESSION ON SCHOLASTIC COMPETENCE IN PRIMARY SCHOOL CHILDREN
The construct of Emotional Intelligence (EI) has been studied as a potential predictor of a good physical and psychological health. Among the different possible EI formulations, Trait EI can act as an important predictor for the good development of psychological wellbeing and social interaction during childhood, and individual differences in trait EI can be relevant for a positive adaptation, emotional competence, socio- emotional behavior and scholastic results within the school context. The present pilot study is a cross-sectional design that involved 150 children aged 8-10 years from several primary schools located in Sicily. This study is part of a larger research project and data colle…
Surgical Antimicrobial Prophylaxis in Pediatric Patients Undergoing Plastic Surgery: A RAND/UCLA Appropriateness Method Consensus Study
For many years, it was clearly shown that surgical procedures might be associated with surgical site infection (SSI). Many scientific institutions prepared guidelines to use in surgery to reduce abuse and misuse of antibiotics. However, in the general guidelines for surgical antibiotic prophylaxis, plastic surgical procedures are not addressed or are only marginally discussed, and children were almost systematically excluded. The main aim of this Consensus document is to provide clinicians with recommendations on antimicrobial prophylaxis for pediatric patients undergoing plastic surgery. The following scenarios were considered: clean plastic surgery in elective procedures with an exclusive…
La pedagogia del trauma della Shoah
L'attenzione è rivolta alle strategie pedagogiche atte a favorire la gestione di una situazione didattica come quella della Shoah, il tutto previa lettura psicosociale delle dinamiche relazionali tra individui e contesto