6533b834fe1ef96bd129d21f

RESEARCH PRODUCT

Specific recommendations for PROs and HRQoL assessment in allergic rhinitis and/or asthma: a GA(2)LEN taskforce position paper

Braido FBousquet P JBrzoza ZCanonica G WCompalati EFiocchi AFokkens WGerth Van Wijk RLa Grutta SLombardi CMaurer MPinto A MRidolo ESenna G ETerreehorst ITodo Bom ABousquet JZuberbier TBaiardini I

subject

Clinical Trials as TopicRhinitis Allergic PerennialHealth Planning GuidelinesRhinitis Allergic SeasonalAsthmahumanitiesOutcome Assessment (Health Care)Treatment OutcomeResearch DesignRhinitis Allergic Perennial; Humans; Rhinitis Allergic Seasonal; Health Planning Guidelines; Treatment Outcome; Clinical Trials as Topic; Quality of Life; Asthma; Outcome Assessment (Health Care); Research DesignHealth Planning GuidelineOutcome Assessment Health CareQuality of LifeHumansRinite Alérgica SazonalAsmaRhinitiQualidade de VidaHuman

description

The GA(2)LEN taskforce on Patient-Reported Outcomes (PROs) and Health-Related Quality of Life (HRQoL) published in 2009 a position paper concerning PROS and HRQoL assessment in clinical trials on allergy. Because of the specificity of this topic in asthma and rhinitis, specific recommendations are needed. The aim of this position paper is to define PROs and their meaning in asthma and rhinitis research, explore the available tools to provide criteria for a proper choice, identify patient-related factor which could influence PROs assessment, define specific recommendations for assessment, analysis and results spreading, underline the unexplored areas and unmet needs. PROs assessment is gaining increasing importance, and it must be performed with a rigorous methodological procedure and using validated tools. This approach enables to better understand patient-related factors influencing clinical trials and real-life management outcomes, identify patients subgroups that can benefit from specific treatment and management plan and tailor treatment to address PROs (not only physician-defined targets) to improve asthma and rhinitis management.

yearjournalcountryeditionlanguage
2010-01-01
10.1111/j.1398-9995.2010.02383.xhttp://hdl.handle.net/10447/102871