0000000000529812

AUTHOR

Sebastiano Campagna

showing 2 related works from this author

Boosting the properties of a fluorescent dye by encapsulation into halloysite nanotubes

2021

Abstract The synthesis of a new biocompatible bichromophoric system (CURBO) was developed, by connecting the skeleton of the naturally occurring curcumin to a BODIPY derivative. The system exhibited an intense fluorescence band with maximum at about 510 nm in organic solvent, while its emission spectra in aqueous solution were more complicated and slightly red-shifted, due to the effect of aggregation for the poor solubility of the dyad. To overcome these problems, the bichomophoric system has been loaded into the halloysite nanotubes (HNT). The HNT/CURBO nanocomposite, suspended in aqueous solution, showed an intensity of emission in the red region of the spectrum higher than the one exhib…

Materials scienceBiocompatibilityhalloysite bicromophoric systems fluorescent dyadGeneral Chemical EngineeringBodipy02 engineering and technologyengineering.material010402 general chemistryPhotochemistry01 natural sciencesHalloysitechemistry.chemical_compoundHallosytluminescenceSolubilitySettore CHIM/02 - Chimica FisicaAqueous solutionNanocompositedyeProcess Chemistry and TechnologySettore CHIM/06 - Chimica Organica021001 nanoscience & nanotechnologyFluorescenceHallosyt Bodipy luminescence dye0104 chemical sciencesMembranechemistryengineeringBODIPY0210 nano-technology
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A Curcumin-BODIPY Dyad and Its Silica Hybrid as NIR Bioimaging Probes

2022

In this paper we describe the synthesis of a novel bichromophoric system in which an efficient photoinduced intercomponent energy transfer process is active. The dyad consists of one subunit of curcumin and one of BODIPY and is able to emit in the far-red region, offering a large Stokes shift, capable of limiting light scattering processes for applications in microscopy. The system has been encapsulated in MCM-41 nanoparticles with dimensions between 50 and 80 nm. Both the molecular dyad and individual subunits were tested with different cell lines to study their effective applicability in bioimaging. MCM-41 nanoparticles showed no reduction in cell viability, indicating their biocompatibil…

Boron CompoundsNIR probeOrganic Chemistryluminescence curcumin BODIPY NIR probes bioimaging bichromophoric dyadGeneral MedicineSettore CHIM/06 - Chimica OrganicaSilicon DioxideCatalysisComputer Science ApplicationsInorganic ChemistryBODIPYNIR probesluminescencebichromophoric dyadSettore BIO/14 - FarmacologiaNanoparticlescurcuminluminescence; curcumin; BODIPY; NIR probes; bioimaging; bichromophoric dyadPhysical and Theoretical ChemistrybioimagingMolecular BiologySpectroscopy
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