The unusual multiwavelength properties of the gamma-ray source PMN J1603-4904

We investigate the nature and classification of PMNJ1603-4904, a bright radio source close to the Galactic plane, which is associated with one of the brightest hard-spectrum gamma-ray sources detected by Fermi/LAT. It has previously been classified as a low-peaked BL Lac object based on its broadband emission and the absence of optical emission lines. Optical measurements, however, suffer strongly from extinction and the absence of pronounced short-time gamma-ray variability over years of monitoring is unusual for a blazar. We are combining new and archival multiwavelength data in order to reconsider the classification and nature of this unusual gamma-ray source. For the first time, we stud…

Third Eular Workshop on Rheumatology Research

Structural Variability of 3C 111 on Parsec Scales

We discuss the parsec-scale structural variability of the extragalactic jet 3C111 related to a major radio flux density outburst in 2007. The data analyzed were taken within the scope of the MOJAVE, UMRAO, and F-GAMMA programs, which monitor a large sample of the radio brightest compact extragalactic jets with the VLBA, the University of Michigan 26 m, the Effelsberg 100 m, and the IRAM 30m radio telescopes. The analysis of the VLBA data is performed by fitting Gaussian model components in the visibility domain. We associate the ejection of bright features in the radio jet with a major flux-density outburst in 2007. The evolution of these features suggests the formation of a leading compone…

A thin absorbing layer at the center of a Fabry-Pérot interferometer

The influence of a dye (Rhodamin B) dissolved in solution or adsorbed at an interface at the center of a Fabry-Perot interferometer on the transmission was investigated both experimentally and theoretically. We show that (i) spectra of extremely thin films are measurable at sub-monolayer concentration (one monolayer reduces the transmission by ≃50%), (ii) the transmission is sensitive to the location of an extremely thin film within nm range and (iii) the absorption coefficient is determined quantitatively by comparison between theory and experiment thus permitting one to estimate the local concentration. The results are relevant for the use of dye probes to monitor changes of organic inter…

ANTARES constrains a blazar origin of two IceCube PeV neutrino events

Abstract Context. The source(s) of the neutrino excess reported by the IceCube Collaboration is unknown. The TANAMI Collaboration recently reported on the multiwavelength emission of six bright, variable blazars which are positionally coincident with two of the most energetic IceCube events. Objects like these are prime candidates to be the source of the highest-energy cosmic rays, and thus of associated neutrino emission. Aims. We present an analysis of neutrino emission from the six blazars using observations with the ANTARES neutrino telescope. Methods. The standard methods of the ANTARES candidate list search are applied to six years of data to search for an excess of muons and hence th…

The Gamma-Ray Emitting Radio-Loud Narrow-Line Seyfert 1 Galaxy PKS 2004-447 II. The Radio View

Gamma-ray detected radio-loud narrow-line Seyfert 1 (g-NLS1) galaxies constitute a small but interesting sample of the gamma-ray loud AGN. The radio-loudest g-NLS1 known, PKS 2004-447, is located in the southern hemisphere and is monitored in the radio regime by the multiwavelength monitoring program TANAMI. We aim for the first detailed study of the radio morphology and long-term radio spectral evolution of PKS 2004-447, which are essential to understand the diversity of the radio properties of g-NLS1s. The TANAMI VLBI monitoring program uses the Australian Long Baseline Array (LBA) and telescopes in Antarctica, Chile, New Zealand, and South Africa to monitor the jets of radio-loud active …

First M87 Event Horizon Telescope Results. VIII. Magnetic Field Structure near The Event Horizon

Full list of authors: Akiyama, Kazunori; Algaba, Juan Carlos; Alberdi, Antxon; Alef, Walter; Anantua, Richard; Asada, Keiichi; Azulay, Rebecca; Baczko, Anne-Kathrin; Ball, David; Baloković, Mislav; Barrett, John; Benson, Bradford A.; Bintley, Dan; Blackburn, Lindy; Blundell, Raymond; Boland, Wilfred; Bouman, Katherine L.; Bower, Geoffrey C.; Boyce, Hope Bremer, Michael; Brinkerink, Christiaan D.; Brissenden, Roger; Britzen, Silke; Broderick, Avery E.; Broguiere, Dominique; Bronzwaer, Thomas; Byun, Do-Young; Carlstrom, John E.; Chael, Andrew; Chan, Chi-kwan; Chatterjee, Shami; Chatterjee, Koushik; Chen, Ming-Tang; Chen, Yongjun; Chesler, Paul M.; Cho, Ilje; Christian, Pierre; Conway, John E.…

Radio and gamma-ray properties of extragalactic jets from the TANAMI sample

Using high-resolution radio imaging with VLBI techniques, the TANAMI program has been observing the parsec-scale radio jets of southern (declination south of -30{\deg}) gamma-ray bright AGN simultaneously with Fermi/LAT monitoring of their gamma-ray emission. We present the radio and gamma-ray properties of the TANAMI sources based on one year of contemporaneous TANAMI and Fermi/LAT data. A large fraction (72%) of the TANAMI sample can be associated with bright gamma-ray sources for this time range. Association rates differ for different optical classes with all BL Lacs, 76% of quasars and just 17% of galaxies detected by the LAT. Upper limits were established on the gamma-ray flux from TAN…

Coincidence of a high-fluence blazar outburst with a PeV-energy neutrino event

The discovery of extraterrestrial very-high-energy neutrinos by the IceCube collaboration has launched a quest for the identification of their astrophysical sources. Gamma-ray blazars have been predicted to yield a cumulative neutrino signal exceeding the atmospheric background above energies of 100 TeV, assuming that both the neutrinos and the gamma-ray photons are produced by accelerated protons in relativistic jets. Since the background spectrum falls steeply with increasing energy, the individual events with the clearest signature of being of an extraterrestrial origin are those at PeV energies. Inside the large positional-uncertainty fields of the first two PeV neutrinos detected by Ic…

Efficacy and Safety of Multiple Doses of Imab362 in Patients with Advanced Gastro-Esophageal Cancer: Results of a Phase Ii Study

ABSTRACT Aim: IMAB362 is a monoclonal antibody specifically targeting claudin 18 isoform 2 (CLDN18.2), which is expressed on gastric cancer cells, whereas it is only present on a fraction of healthy stomach cells. This may reduce the risk of target-related side effects. Single-agent IMAB362 appears safe in patients with advanced gastro-esophageal cancer (GEC) based on data from a phase I trial. Methods: This international, multicenter, non-randomized phase IIa study (NCT01197885) investigated the efficacy and safety of repeated doses of IMAB362 (300 and 600 mg/m2) in patients with metastatic, refractory/recurrent, CLDN18.2-positive GEC (i.e. cancer of the stomach, the lower esophagus and th…

Constraining the neutrino emission of gravitationally lensed Flat-Spectrum Radio Quasars with ANTARES data

This paper proposes to exploit gravitational lensing effects to improve the sensitivity of neutrino telescopes to the intrinsic neutrino emission of distant blazar populations. This strategy is illustrated with a search for cosmic neutrinos in the direction of four distant and gravitationally lensed Flat-Spectrum Radio Quasars. The magnification factor is estimated for each system assuming a singular isothermal profile for the lens. Based on data collected from 2007 to 2012 by the ANTARES neutrino telescope, the strongest constraint is obtained from the lensed quasar B0218+357, providing a limit on the total neutrino luminosity of this source of 1.08×10^46 erg s-1. This limit is about one o…

The gamma-ray emitting radio-loud narrow-line Seyfert 1 galaxy PKS 2004-447 I. The X-ray View

As part of the TANAMI multiwavelength progam, we discuss new X-ray observations of the $\gamma$-ray and radio-loud Narrow Line Seyfert galaxy ($\gamma$-NLS1) PKS 2004-447. The active galaxy is a member of a small sample of radio-loud NLS1s detected in $\gamma$-rays by the Fermi Large Area Telescope. It is the radio-loudest and only southern-hemisphere source in this sample. We present results from our X-ray monitoring program comprised of Swift snapshot observations from 2012 through 2014 and two new X-ray observations with XMM-Newton in 2012. We analyze the X-ray spectrum and variability of this peculiar source using supplementary archival data from 2004 and 2011. The (0.5-10) keV spectrum…

Dynamic SEDs of southern blazars - DSSB

The Dynamic SEDs of southern blazars catalog is based on a TANAMI multiwavelength project that has been monitoring a sample of 22 radio-loud blazars of the southern sky from radio to gamma-ray wavelengths. (4 data files). Simultaneous broadband spectral and temporal studies of blazars are an important tool for investigating active galactic nuclei (AGN) jet physics. Aims. We study the spectral evolution between quiescent and flaring periods of 22 radio-loud AGN through multiepoch, quasi-simultaneous broadband spectra. For many of these sources these are the first broadband studies. Methods. We use a Bayesian block analysis of Fermi/LAT light curves to determine time ranges of constant flux f…