0000000000530743

AUTHOR

Marco Ventura

showing 2 related works from this author

Ranking the impact of human health disorders on gut metabolism: Systemic lupus erythematosus and obesity as study cases

2015

Multiple factors have been shown to alter intestinal microbial diversity. It remains to be seen, however, how multiple collective pressures impact the activity in the gut environment and which, if any, is positioned as a dominant driving factor determining the final metabolic outcomes. Here, we describe the results of a metabolome-wide scan of gut microbiota in 18 subjects with systemic lupus erythematosus (SLE) and 17 healthy control subjects and demonstrate a statistically significant difference (p < 0.05) between the two groups. Healthy controls could be categorized (p < 0.05) based on their body mass index (BMI), whereas individuals with SLE could not. We discuss the prevalence of SLE c…

AdultAutoimmunityGut floramedicine.disease_causeArticleAutoimmunityBody Mass IndexmedicineHomeostasisHumansLupus Erythematosus SystemicMetabolomicsClinical significanceMicrobiomeObesityMultidisciplinaryLupus erythematosusbiologyMicrobiotaCase-control studyMiddle Agedmedicine.diseasebiology.organism_classificationObesityN-Acetylneuraminic AcidGastrointestinal TractCase-Control StudiesImmunologyMetabolomeFemaleMicrobiomeBody mass indexMetabolic Networks and PathwaysScientific Reports
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Phage Biodiversity in Artisanal Cheese Wheys Reflects the Complexity of the Fermentation Process

2017

Dairy fermentations constitute a perfect “breeding ground” for bacteriophages infecting starter cultures, particularly strains of Lactococcus lactis. In modern fermentations, these phages typically belong to one of three groups, i.e., the 936, P335, and c2 phage groups. Traditional production methods present fewer chemical and physical barriers to phage proliferation compared to modern production systems, while the starter cultures used are typically complex, variable, and undefined. In the current study, a variety of cheese whey, animal-derived rennet, and vat swab samples from artisanal cheeses produced in Sicily were analysed for the presence of lactococcal phages to assess phage div…

0301 basic medicineHot TemperaturevirusesLactococcusLactococcu030106 microbiologylcsh:QR1-502Bacteriophage; Cheese; Dairy fermentation; Infection; Lactococcus lactis; Animals; Bacteriophages; Cheese; Fermentation; Genetic Variation; Genome Bacterial; Hot Temperature; Lactococcus; Microbial Viability; Phylogeny; Sequence Analysis DNA; Sicily; Whey; Biodiversity; Infectious Diseases; VirologyInfectious Diseasebacteriophage; <i>Lactococcus lactis</i>; dairy fermentation; cheese; infectionArticlelcsh:MicrobiologyDairy fermentationMicrobiologyBacteriophageSettore AGR/17 - Zootecnica Generale E Miglioramento Genetico03 medical and health sciencesStarterCheesePhylogeneticsWheyVirologyLactococcusAnimalsBacteriophagesFood scienceLactococcus lactiBacteriophageSicilyPhylogenyGenetic diversityMicrobial ViabilitybiologyAnimalLactococcus lactisGenetic VariationSequence Analysis DNABiodiversitybiology.organism_classificationLactococcus lactisInfectious DiseasesFermentationFermentationRennetInfectionGenome BacterialSettore AGR/16 - Microbiologia AgrariaViruses
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