0000000000532362

AUTHOR

Gambarini G

Study of optical absorbance and MR relaxation of irradiated Fricke Xylenol Orange Gel Dosimeters

Studies on the optical absorbance spectra of Fricke xylenol orange gel dosimeters were performed, in the wavelength range from 300 nm to 800 nm, in order to highlight some particular characteristics that can affect the achievable precision. The spectra are different mainly due to the different types of xylenol orange that was used and to a lower extent due to the different gelling agents (agarose or gelatine). The characteristic of variation of absorbance spectra versus dose, however, are similar in the various cases and can explain some peculiarities, as apparent effects of dose threshold. Changes of spectral shapes appear over the time after irradiation. Magnetic resonance measurements pe…

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Studio di assorbanza ottica e rilassometria RM in dosimetri a gel di Fricke

I dosimetri a gel di Fricke con xylenol-orange, analizzati otticamente, presentano alcune limitazioni se impiegati per misure di basse dosi (pochi Gy o meno), per irraggiamenti di lunga durata o per individuare procedure di calibrazione che permettano l'utilizzo in radioterapia. Le difficoltà derivano da variazioni nello spettro di assorbanza verosimilmente dovute a variazioni dei legami degli ioni ferrici con lo xylenol-orange. Sono state effettuate misure: i) di assorbanza ottica, anche spettrometrica, per dosimetri irraggiati a diverse dosi e a diversi tempi rispetto all'irraggiamento; ii) di rilassometria RM per valutare le variazioni dovute al solo aumento del numero di ioni ferrici.

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Novel dosimetric gels for three-dimensional dose mapping in radiotherapy

One of the most recent and promising developments for radiotherapy (RT) dosimetry was the introduction of 3D radiation- sensitive gels. The gels are tissue equivalent, so they also serve as a phantom, and their response is largely independent of rad iation quality and dose rate. Some gels are infused with ferrous sulfate and rely on the radiation-induced oxidation of ferrous ions to ferric ions (Fricke-gels) . These gels suffer from spontaneous-oxidation and diffusion of ferric ions after irradiation; the latter is significantly reduced by chelating agents such as xylenol orange (XO) (Fricke-XO gels) [2]. Other formulations consist of dispersed monomers, and rely on radiation-induced cross-…

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