0000000000535827

AUTHOR

Lars Budäus

showing 2 related works from this author

Impact of preoperative risk on metastatic progression and cancer-specific mortality in patients with adverse pathology at radical prostatectomy.

2017

Objective To evaluate the impact of preoperative risk category on metastatic disease and prostate cancer-specific mortality (CSM) in patients with prostate cancer (PCa) with adverse pathology at radical prostatectomy (RP). Patients and Methods The records of 6 943 patients who underwent RP at a European tertiary centre were analysed. Biochemical recurrence (BCR), metastatic disease and CSM were assessed for patients with adverse pathology at RP, and stratified according to preoperative low- vs intermediate-/high-risk PCa groups. Kaplan–Meier, cumulative incidence, Cox regression and competing risk regression analyses were performed. Results In patients with extracapsular extension, the meta…

Biochemical recurrenceMalemedicine.medical_specialtyPathologyUrologymedicine.medical_treatment030232 urology & nephrologyUrologyKaplan-Meier EstimateLower riskCohort Studies03 medical and health sciencesProstate cancer0302 clinical medicineRisk FactorsMedicineHumansCumulative incidencePathologicalAgedProstatectomybusiness.industryProportional hazards modelProstatectomyHazard ratioProstatic NeoplasmsMiddle AgedProstate-Specific Antigenmedicine.disease030220 oncology & carcinogenesisMultivariate AnalysisbusinessBJU international
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Antimicrobial Lubricant Did Not Reduce Infection Rate in Transrectal Biopsy Patients in a Large Randomized Trial Due to Low Complication Rates

2018

Abstract Background Transrectal prostate biopsy (pbx) is the most frequent outpatient procedure in the urological field. Septic complications are a major health issue. Objective To evaluate complication rates with or without an antimicrobial lubricant. Design, setting, and participants A total of 1000 patients received pbx between 2013 and 2015. Information about complications was collected by a 3-wk questionnaire. Return rate was 73.2% (n = 732). Intervention Randomization for pbx with the instillation of an antimicrobial lubricant (intervention group, n = 385) or the standard lubricant (control group, n = 347) was performed. Outcome measurements and statistical analysis Multivariable anal…

Image-Guided BiopsyMalemedicine.medical_specialtyProstate biopsyFeverUrology030232 urology & nephrologyPatient ReadmissionHematospermialaw.invention03 medical and health sciencesPostoperative Complications0302 clinical medicineRandomized controlled triallawGermanyInternal medicineBiopsymedicineHumansProspective StudiesAgedHematuriaLubricantsmedicine.diagnostic_testbusiness.industryUrinary retentionProstateRectumProstatic NeoplasmsAntibiotic ProphylaxisHemospermiaUrinary RetentionAnti-Bacterial AgentsTransrectal biopsy030220 oncology & carcinogenesisInternational Prostate Symptom Scoremedicine.symptomGastrointestinal HemorrhageComplicationbusinessEuropean Urology Focus
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