A Multicomponent Exercise Intervention that Reverses Frailty and Improves Cognition, Emotion, and Social Networking in the Community-Dwelling Frail Elderly: A Randomized Clinical Trial

Abstract Background Frailty can be an important clinical target to reduce rates of disability. Objective To ascertain if a supervised-facility multicomponent exercise program (MEP) when performed by frail older persons can reverse frailty and improve functionality; cognitive, emotional, and social networking; as well as biological biomarkers of frailty, when compared with a controlled population that received no training. Design This is an interventional, controlled, simple randomized study. Researchers responsible for data gathering were blinded for this study. Setting Participants from 2 primary rural care centers (Sollana and Carcaixent) of the same health department in Spain were enroll…