0000000000538376

AUTHOR

C. Zotti

showing 2 related works from this author

Assessment of humoral and cell-mediated immunity against Bordetella pertussis in adolescent, adult, and senior subjects in Italy

2008

SUMMARYHumoral and cell-mediated immunity (CMI) againstB. pertussiswas assessed in a sample of adolescent, adult and senior subjects distributed in five different geographical areas in Italy. Most (99·1%) subjects had IgG anti-pertussis toxin (PT) antibodies exceeding the minimum detection level [⩾2 ELISA units (EU)/ml]. There were no significant differences between the genders; 6·2% samples recorded titres ⩾100 EU/ml. CMI was positive [stimulation index (SI) ⩾5] against PT in 39·0% of all samples. This study suggests thatB. pertussiscontinues to circulate in age groups that have been previously considered to be uninvolved in the circulation of this pathogen and that adolescent and adult pe…

MaleSettore MED/07 - Microbiologia E Microbiologia ClinicaCellular immunityBordetella pertussisEpidemiologyWhooping CoughBordetella pertussisSeroepidemiologic StudiesEpidemiology80 and overLymphocytesAged 80 and overeducation.field_of_studybiologyadultBacterialMiddle AgedOriginal PapersAntibodies BacterialseniorInfectious DiseasesB. pertussis Humoral and cell-mediated immunity ELISAItalyFemaleAntibodyAdultmedicine.medical_specialtyBordetella pertussiAdolescent; Adult; Aged; Aged 80 and over; Antibodies Bacterial; Antitoxins; Bordetella pertussis; Enzyme-Linked Immunosorbent Assay; Female; Humans; Immunoglobulin G; Italy; Lymphocytes; Male; Middle Aged; Seroepidemiologic Studies; Whooping Cough; Epidemiology; Infectious DiseasesAdolescentPopulationEnzyme-Linked Immunosorbent AssayAntibodiesNOImmunitymedicineHumanseducationimmunità cellulo mediataAgedbusiness.industrybiology.organism_classificationadolescentImmunoglobulin GHumoral immunityImmunologyEtiologybiology.proteinimmunità umoraleAntitoxinsbusiness
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Monitoring the rate of hospitalization before rotavirus immunization in Italy utilizing ICD9-CM regional databases

2009

BACKGROUND: Recently, two Rotavirus (RV) vaccines were licensed in Italy, rendering RV illness a vaccine preventable disease. To assess the RV hospitalization rate in Italy, a study focused on the Regional hospital discharge forms (HDD) databases was carried out. RESULTS: Regional HDD databases from Piemonte, Veneto, Friuli-Venezia-Giulia and Marche were analyzed. A total of 434,335 hospitalizations were counted in the study timeframe and 13,234 VE diagnoses (3% of hospitalizations) were collected. A total of 8546 RVE cases (2% of hospitalizations, 64% of all VE) were observed, of which 1.2% were primary diagnoses (PD) and 0.8% secondary diagnosis (SD). The RVE hospitalization peak (4.9%) w…

RotavirusPediatricsmedicine.medical_specialtyDatabases FactualSettore MED/17 - Malattie InfettiveSettore MED/42 - Igiene Generale e ApplicataImmunologymedicine.disease_causecomputer.software_genreimmunizationRotavirus InfectionsHospitalization rateEnteritisrotavirus; immunization; regional databasesRotavirusvaccineMedicineHumansICD9-CMGeneral Pharmacology Toxicology and PharmaceuticsenteritisdatabaserotaviruDatabasebusiness.industryData CollectionInfant NewbornInfantSecondary diagnosismedicine.diseasevaccinationregional databasesRotavirus; enteritis; vaccine; hospitalization; ICD9-CM; databaseVaccinationRegional hospitalImmunizationItalyChild PreschoolbusinesscomputerViral enteritishospitalization
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