0000000000539914

AUTHOR

Jérôme Schoenhentz

showing 2 related works from this author

Perfluoroalkylated amphiphilic MUC1 glycopeptide antigens as tools for cancer immunotherapy.

2010

The synthesis of perfluoroalkylated glycopeptide antigens and their specific binding to anti-MUC1 mouse antibodies is reported.

medicine.medical_treatmentdigestive systemCatalysisAntibodiesAntigen-Antibody ReactionsMiceAntigenCancer immunotherapyNeoplasmsAmphiphileMaterials ChemistrymedicineAnimalsAntigensskin and connective tissue diseasesneoplasmsMUC1Mice Inbred BALB CBinding SitesbiologyMolecular StructureChemistryMucin-1Metals and AlloysGlycopeptidesGeneral Chemistrybiological factorsdigestive system diseasesGlycopeptideSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialsBiochemistryCeramics and Compositesbiology.proteinImmunotherapyAntibodyChemical communications (Cambridge, England)
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Langmuir−Blodgett Films of Fluorinated Glycolipids and Polymerizable Lipids and Their Phase Separating Behavior

2010

This paper describes the phase separating behavior of Langmuir monolayers from mixtures of different lipids that (i) either carry already a glycopeptide recognition site or can be easily modified to carry one and (ii) polymerizable lipids. To ensure demixing during compression, we used fluorinated lipids for the biological headgroups and hydrocarbon based lipids as polymerizable lipids. As a representative for a lipid monomer, which can be polymerized in the hydrophilic headgroup, a methacrylic monomer was used. As a monomer, which can be polymerized in the hydrophobic tail, a lipid with a diacetylene unit was used (pentacosadiynoic acid, PDA). The fluorinated lipids were on the one hand a …

PolymersSurface PropertiesMicroscopy Atomic ForceLangmuir–Blodgett filmMiscibilityPolymerizationchemistry.chemical_compoundPhase (matter)MonolayerElectrochemistryOrganic chemistryGeneral Materials ScienceLipid bilayer phase behaviorSpectroscopyDiacetyleneChemistryAirTemperatureWaterFluorineSurfaces and InterfacesCondensed Matter PhysicsLipidsHydrocarbonsMonomerModels ChemicalPolymerizationChemical engineeringFatty Acids Unsaturatedlipids (amino acids peptides and proteins)GlycolipidsCrystallizationLangmuir
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