0000000000541571

AUTHOR

O. M. Granata

showing 2 related works from this author

17b-hydroxysteroid oxidoreductase activity in intact cells significantly differs from classical enzymology analysis

1996

17b-hydroxysteroid oxidoreductaseSettore BIO/10 - Biochimica
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Steroid Patterns of Benign Breast Disease

1990

We briefly review some biochemical aspects of benign breast disease (BBD), mainly focusing on free and conjugate estrogen content of breast cyst fluid (BCF), also in relation to cyst type. Evidence is reported that high K(+)-type I-cysts clearly associate with low Cl- levels and accumulate significantly higher quantities of dehydroepiandrosterone sulfate (DHAS) and estrone-3-sulfate (E1S). In spite of the limited number of cases, both increasing DHAS and E1S levels correlate with the increment of K+ to Na+ ratio. A positive correlation was also found between DHAS and E1S. Using electrochemical detection (ECD) on-line to high performance liquid chromatography (HPLC) in the reverse phase mode…

medicine.medical_specialtyEstronemedicine.drug_classmedicine.medical_treatmentBreast NeoplasmsEstroneGeneral Biochemistry Genetics and Molecular BiologySteroidchemistry.chemical_compoundDehydroepiandrosterone sulfateBreast cancerHistory and Philosophy of ScienceInternal medicinemedicineHumansCystFibrocystic Breast DiseaseChromatography High Pressure LiquidDehydroepiandrosterone SulfateGeneral NeuroscienceSulfataseEstrogensDehydroepiandrosteroneMiddle Agedmedicine.diseaseEndocrinologychemistryEstrogenFemaleBreast diseaseAdenofibromaAnnals of the New York Academy of Sciences
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