0000000000542223

AUTHOR

Anna Klonowski

showing 3 related works from this author

Realität der Versorgungssituation der Gicht: Daten zur Klinik, Epidemiologie und Komorbiditäten von 4016 Patienten in Rheinland-Pfalz

2019

Zusammenfassung Einleitung Ziel dieser Datenerhebung war die Untersuchung der klinischen, demografischen und Komorbidität-assoziierten Daten der Gicht sowie der klinischen Praxis der hausärztlichen Gichtversorgung in Rheinland-Pfalz (RL-P). Methoden Gicht-spezifische Fragebögen wurden über die kassenärztliche Vereinigung an alle Hausarztpraxen in RL-P versendet. Die Fragebögen setzten sich aus Items zur Erfassung von Epidemiologie, Medikation und Komorbiditäten zusammen. Darüber hinaus wurden Fragen zur klinischen Manifestation der Gicht mit einem besonderen Fokus auf therapierefraktäre Fälle eingebunden. Schließlich wurden die Hausärzte angehalten, den aktuellen Versorgungsstatus anhand ei…

030203 arthritis & rheumatologyGynecology03 medical and health sciencesmedicine.medical_specialty0302 clinical medicinebusiness.industryMedicine030212 general & internal medicineGeneral MedicinebusinessDMW - Deutsche Medizinische Wochenschrift
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THU0366 SYSTEMATIC CORONARY RISK EVALUATION (SCORE) MISCLASSIFIES CARDIOVASCULAR RISK IN ANTISYNTHETASE SYNDROME: RESULTS OF THE PILOT MULTICENTRIC S…

2020

Background:Antisynthetase Syndrom (ASyS) is an autoimmune overlap disease characterized by antiaminoacyl-tRNA-synthetase (anti-ARS) antibodies and the classic triad of arthritis, myositis and interstitial lung disease (ILD) (1). Markers of cardiovascular (CV) or cerebrovascular (CVB) risk have never been examined in ASyS.Objectives:Aim of this study (RIsk of CARdiovascular Disease in ASyS: RI.CAR.D.A.) was to test the ability of an established traditional CV risk prediction score (Systematic Coronary Risk Evaluation-SCORE) and its EULAR modified version (mSCORE) to identify ASyS patients at high CV risk. Moreover, we sought to examine for the first time associations of CV surrogate markers …

medicine.medical_specialtybusiness.industryImmunologyInterstitial lung diseaseArthritisAntisynthetase syndromeGold standard (test)Arteriosclerosismedicine.diseaseGeneral Biochemistry Genetics and Molecular BiologyRheumatologyRheumatologyInternal medicinemedicineCardiologyImmunology and AllergybusinessMyositisSubclinical infectionAnnals of the Rheumatic Diseases
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Possible misclassification of cardiovascular risk by SCORE in antisynthetase syndrome: results of the pilot multicenter study RI.CAR.D.A

2020

Abstract Objectives To test the ability of an established traditional cardiovascular (CV) risk prediction score [Systematic COronary Risk Evaluation (SCORE)] and its EULAR modified version (mSCORE) to identify antisynthetase syndrome (ASyS) patients at high CV risk and to examine for the first time associations of CV and cerebrovascular surrogate markers with clinical and immunological ASyS parameters. Methods SCORE/mSCORE and the gold standard marker of aortic stiffness [carotid-femoral pulse wave velocity (cfPWV)] were examined in ASyS patients and healthy controls. Moreover, sonography of the common- (CCA) and internal- (ICA) carotid arteries was performed in subsets of both groups, eval…

AdultCarotid Artery DiseasesMaleCarotid atherosclerosismedicine.medical_specialtyPilot ProjectsAntisynthetase syndrome030204 cardiovascular system & hematologyCarotid Intima-Media Thickness03 medical and health sciencesVascular Stiffness0302 clinical medicineRheumatologyInternal medicineDiabetes mellitusHumansMedicinePharmacology (medical)Prospective StudiesPulse wave velocitySubclinical infection030203 arthritis & rheumatologyMyositisbiologybusiness.industryConfoundingGold standard (test)Middle Agedmedicine.diseaseCarotid ArteriesCross-Sectional StudiesHeart Disease Risk FactorsCase-Control Studiescardiovascular systembiology.proteinCardiologyFemaleCreatine kinasebusinessRheumatology
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