0000000000544397

AUTHOR

Domenico Fedele

showing 4 related works from this author

Does ethanol intake interfere with the evaluation of glycated hemoglobins?

1989

Ethanol and/or its metabolites interfere with the chromatographic assay of glycated hemoglobins. Fasting plasma glucose, blood ethanol, HbA(1), HbA(1c), HbA(1a+b), MCV and GGT were determined in 22 control subjects; 22 alcoholics, 22 diabetic patients and 22 alcoholic diabetic patients. Fasting plasma glucose and all hemoglobin fractions were lower in alcoholic subjects and, except for HbA(1a+b), higher in diabetic patients and in alcoholic diabetic patients. HbA(1), and HbA(1c) correlated well with plasma glucose but not with blood ethanol, MCV and GGT. Glycated hemoglobin was not found to be a useful marker for alcohol abuse. With the chromatographic method we used, the evaluation of glyc…

Blood GlucoseMalemedicine.medical_specialtyAlcohol DrinkingEndocrinology Diabetes and MetabolismAlcohol abusechemistry.chemical_compoundEndocrinologyInternal medicineDiabetes mellitusInternal MedicinemedicineDiabetes MellitusHumansGlycated HemoglobinEthanolEthanolbusiness.industryGeneral MedicineFastingMiddle Agedmedicine.diseaseControl subjectsAlcoholismEndocrinologyDiabetes Mellitus Type 1chemistryDiabetes Mellitus Type 2Metabolic control analysisFemaleGlycated hemoglobinHemoglobinEthanol intakebusinessActa diabetologica latina
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Red cell sorbitol concentration in relation to short- and medium-term variation of plasma glucose.

1989

To evaluate the time course of changes in red cell sorbitol (RCS) concentration in relation to variations of plasma glucose levels, RCS was determined in 7 normal subjects during i.v. glucose infusion (IVGTT); in 6 hyperglycemic insulin-dependent diabetic subjects while glycemia was normalized with Biostator GC 115 and in 4 diabetic patients in previously poor metabolic control, in whom normal glycemia was obtained in 8–10 days by intensive insulin therapy. During IVGTT, plasma glucose levels increased with significant differences from baseline at 5, 10, 16, 25, 60, 100 and 160 min and returned to basal levels after 3h; RCS concentration showed small and insignificant increases. During i.v.…

Activity CyclesBlood GlucoseMalemedicine.medical_specialtyEndocrinology Diabetes and Metabolismmedicine.medical_treatmentmacromolecular substancesMedium termchemistry.chemical_compoundEndocrinologyReference ValuesInternal medicineDiabetes mellitusInternal MedicinemedicineHumansSorbitolPlasma glucoseRed Cellbusiness.industryInsulinGeneral MedicineGlucose Tolerance TestMiddle Agedmedicine.diseaseCircadian RhythmEndocrinologyDiabetes Mellitus Type 1GlucoseBasal (medicine)chemistryMetabolic control analysisHyperglycemiaSorbitolbusinessActa diabetologica latina
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Diabetes and coronary risk factors. Relative risk for single factors and aggregation of more factors in a general population sample from northern Ita…

1990

In the course of a general population survey in Mirano (Venice), Northern Italy, a random sample of 1,903 subjects (50.1% men) aged 20-59 was examined. Fifty-five were diabetic (fasting plasma glucose greater than or equal to 140 mg/dl or diagnosed by a physician) and 1,670 non-diabetic subjects (fasting plasma glucose below 110 mg/dl). In this paper an assessment was made on the more frequent occurrence of coronary risk factors (serum cholesterol and triglycerides, body mass index (BMI), systolic blood pressure, cigarette smoking) and, in particular, of their aggregation in diabetic patients as compared to non-diabetic controls. The occurrence of any one of the coronary risk factors studie…

AdultMaleRural Populationmedicine.medical_specialtyEndocrinology Diabetes and MetabolismBlood PressureCoronary DiseaseBody Mass IndexDiabetes Complicationschemistry.chemical_compoundSex FactorsEndocrinologyRisk FactorsDiabetes mellitusInternal medicineEpidemiologyInternal MedicinemedicineHumansTriglyceridesCholesterolbusiness.industrySmokingAge FactorsCoronary risk factorsGeneral MedicineMiddle Agedmedicine.diseaseNorthern italyCholesterolBlood pressureEndocrinologyItalychemistryRelative riskFemalebusinessBody mass indexActa Diabetologica Latina
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Glycated serum proteins and glucose tolerance

1988

Glycated serum proteins (GSP), stable glycated hemoglobin (HbA1c) together with some metabolic parameters were evaluated in 120 subjects, 30 with normal glucose tolerance (NGT), 30 with impaired glucose tolerance (IGT), 30 with non-insulin-dependent diabetes mellitus (NIDD), and 30 with insulin-dependent diabetes mellitus (IDD). GSP levels were significantly higher in IGT, NIDD and IDD than in NGT. HbA1c levels were not significantly higher in IGT in comparison with NGT, but were significantly higher in NIDD and in IDD than in NGT and IGT. GSP correlated better than HbA1c with all metabolic parameters considered. Taking into account the distribution of the values, GSP showed a smaller overl…

AdultBlood GlucoseMalemedicine.medical_specialtyGlycosylationendocrine system diseasesEndocrinology Diabetes and MetabolismImpaired glucose toleranceHba1c levelchemistry.chemical_compoundEndocrinologystomatognathic systemReference ValuesInternal medicineDiabetes mellitusInternal MedicinemedicineHumansTriglyceridesGlycated HemoglobinGlucose tolerance testmedicine.diagnostic_testbusiness.industryCholesterolnutritional and metabolic diseasesBlood ProteinsGeneral MedicineGlucose Tolerance TestMiddle Agedmedicine.diseaseBlood proteinsCholesterolDiabetes Mellitus Type 1EndocrinologyDiabetes Mellitus Type 2chemistryHyperglycemiaMetabolic control analysisFemaleGlycated hemoglobinbusinesshormones hormone substitutes and hormone antagonistsActa Diabetologica Latina
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