Author: Takashi Hirano

0000000000546991

AUTHOR

Takashi Hirano

showing 2 related works from this author

Synthesis of activated cyclophosphamide derivatives bearing functional groups

1979

Aus Cyclophosphamid (I) erhalt man mit Ozon das Hydroperoxid (IIa), das mit Triethylphosphit zu (IIb) reduziert und dann in Trifluoressigsaure mit entsprechenden Thioverbindungen zu zahlreichen Thioethern (III) mit funktionellen Gruppen substituiert werden kann . Diese werden auf Antitumorwirkung untersucht.

CyclophosphamideChemistryStereochemistryOrganic ChemistryDrug DiscoverymedicineOrganic chemistryBiochemistrymedicine.drugTetrahedron Letters

researchProduct

1979

chemistry.chemical_classificationChemotherapychemistryCyclophosphamidemedicine.medical_treatmentPolymer chemistryDrug deliverymedicinePolymerPharmacologymedicine.drugDie Makromolekulare Chemie

researchProduct

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