0000000000547841

AUTHOR

Martin Bettag

showing 2 related works from this author

Effects of laser-induced thermotherapy (LITT) on proliferation and apoptosis of glioma cells in rat brain transplantation tumors.

2002

Background and Objectives Laser-induced thermotherapy (LITT) is an approach to the treatment of brain tumors especially in poorly accessible regions. Its clinical applicability with tumor cell destruction has been shown in several studies. However, no data are known about specific effects on tumors cells due to LITT in the time course of the lesion. Study Design/Materials and Methods LITT was performed in adult Lewis rats with implanted glioma cells in the brain using a standard exposure of 3 W for 30 seconds. Before and following LITT, neoplastic lesions were monitored by MRI. Proliferation of implanted cells and gliosis were assessed by several histological techniques and immunohistochemi…

Pathologymedicine.medical_specialtyNecrosisLaser-induced thermotherapyApoptosisDermatologyLesionNecrosisGliomaIn Situ Nick-End LabelingMedicineAnimalsLaser Coagulationbusiness.industryBrain NeoplasmsGliomamedicine.diseaseMagnetic Resonance ImagingSurvival AnalysisRatsTransplantationTreatment OutcomeGliosisApoptosisRats Inbred LewImmunohistochemistrySurgerymedicine.symptombusinessCell DivisionNeoplasm TransplantationLasers in surgery and medicine
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Transoral transclival removal of anteriorly placed cavernous malformations of the brainstem.

2001

BACKGROUND The natural history of brain stem cavernous malformations is unfavorable because of their high hemorrhage rate and resulting neurological deterioration among patients. However, direct surgery of intrinsic and anteriorly situated cavernomas is hazardous and leads to a bad postoperative outcome because of trauma to lateral and dorsally situated eloquent areas of the brain stem. METHODS We review the cases of two patients with symptomatic cavernous malformations of the anterior brain stem and describe the usefulness of a transoral-transclival approach. A 23-year-old man developed progressive hemihypaesthesia and paraesthesia, hemiparesis with gait ataxia, dysarthria, dysphonia, and …

AdultMalemedicine.medical_specialtyNeurological examinationNeurosurgical ProceduresCentral nervous system diseaseClivusmedicineHumansDiplopiaMouthmedicine.diagnostic_testbusiness.industryBrain NeoplasmsCavernous malformationsmedicine.diseaseMagnetic Resonance ImagingSurgerymedicine.anatomical_structureHemiparesisHemangioma CavernousTreatment OutcomeCranial Fossa PosteriorGait AtaxiaSurgeryFemaleNeurology (clinical)medicine.symptombusinessTomography X-Ray ComputedMeningitisBrain StemSurgical neurology
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