A framework for remission in SLE

ObjectivesTreat-to-target recommendations have identified ‘remission’ as a target in systemic lupus erythematosus (SLE), but recognise that there is no universally accepted definition for this. Therefore, we initiated a process to achieve consensus on potential definitions for remission in SLE.MethodsAn international task force of 60 specialists and patient representatives participated in preparatory exercises, a face-to-face meeting and follow-up electronic voting. The level for agreement was set at 90%.ResultsThe task force agreed on eight key statements regarding remission in SLE and three principles to guide the further development of remission definitions:1. Definitions of remission wi…

Proceedings of the 23rd Paediatric Rheumatology European Society Congress: part one

Individualisierte Chirurgie des Rektumprolapses

Patienten zur operativen Behandlung des Rektumprolapses konnen in folgende Gruppen eingeteilt werden: Patienten mit Operation uber den perinealen Zugang; Patienten mit Operation uber den abdominalen Zugang. Wegen der Vielzahl der operativen Varianten und technischen Modifikationen konnen die schwierigen Entscheidungssituationen bereits bei der Wahl des operativen Verfahrens anstehen und sind mit allgemeinen und lokalen Patientenfaktoren verbunden. Zu den lokalen Patientenfaktoren zahlen Prolapslange, Kombination des Rektumprolapses mit anderen Beckenbodensenkungserkrankungen (Genitalprolaps, Rektozele, Zystozele, Deszendens-perinei-Syndrom usw.), spezifische anatomische Rektumkonstellatione…

Respiratory manifestations of eosinophilic granulomatosis with polyangiitis (Churg-Strauss)

The respiratory manifestations of eosinophilic granulomatosis with polyangiitis (EGPA) have not been studied in detail.In this retrospective multicentre study, EGPA was defined by asthma, eosinophilia and at least one new onset extra-bronchopulmonary organ manifestation of disease.The study population included 157 patients (mean±sd age 49.4±14.1 years), with a mean±sd blood eosinophil count of 7.4±6.4×109 L−1 at diagnosis. There was a mean±sd of 11.8±18.2 years from the onset of asthma to the diagnosis of EGPA, of 1.4±8.4 years from the first onset of peripheral eosinophilia to the diagnosis of EGPA, and of 7.4±6.4 years from EGPA diagnosis to the final visit. Despite inhaled and oral corti…