0000000000548244

AUTHOR

Francesca Grippi

0000-0003-1470-6496

showing 5 related works from this author

Serological and Molecular Evidence of Bartonella henselae in Stray Cats from Southern Italy

2021

Bartonella henselae is a slow growing and facultative intracellular pathogen mainly transmitted by arthropod vectors adapted to domestic and wild mammalian reservoir hosts. Since cats are the major source of the B. henselae infection, this study aimed to evaluate the seroprevalence and the DNA presence in randomly sampled stray cats. Blood samples of 429 cats were collected from shelter of Palermo (Southern Italy) and sera and whole blood were analyzed for the presence of antibodies against B. henselae by indirect immunofluorescence assay (IFA) and by real-time polymerase chain reaction (PCR), respectively. Two hundred and three sera (47.3%) were positive to IFA and 148 blood samples (34.5%…

0301 basic medicineMicrobiology (medical)040301 veterinary sciencesQH301-705.5Microbiologylaw.inventionSerology<i>Bartonella henselae</i>0403 veterinary science03 medical and health scienceslawVirologySeroprevalenceBiology (General)PathogenPolymerase chain reactionBartonella henselaeCATSbiologyseroprevalencecats04 agricultural and veterinary sciencesbiology.organism_classificationVirology030104 developmental biologyReal-time polymerase chain reactionbiology.proteinAntibodyreal-time PCRMicroorganisms
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Seroprevalence of Borrelia burgdorferi in Stray Dogs from Southern Italy

2020

Borrelia burgdorferi is a bacterial pathogen transmitted by Ixodes ticks and is responsible for Lyme disease in both humans and dogs. The aim of this work was to evaluate B. burgdorferi diffusion among stray dogs in Palermo (Sicily, Italy) by serological methods in order to study the risk factors associated with the infection. Serum and blood samples of 316 dogs were collected from a shelter in Palermo, and were analyzed for the presence of antibodies against B. burgdorferi by indirect immunofluorescence assay (IFA), and of the ospA gene by real-time PCR, respectively. Seventeen sera (5.4%) were positive for the antibodies via IFA and one blood (0.3%) for ospA via real time PCR. On the basi…

0301 basic medicineMicrobiology (medical)030231 tropical medicineBiologySettore BIO/19 - Microbiologia GeneraleMicrobiologySerology03 medical and health sciences0302 clinical medicineLyme diseaseVirologymedicineSeroprevalenceBorrelia burgdorferilcsh:QH301-705.5PathogenseroprevalenceCommunicationospA gene<i>ospA</i> geneBorrelia burgdorferi seroprevalence030108 mycology & parasitologymedicine.diseasebiology.organism_classificationbacterial infections and mycosesVirologyBreed<i>Borrelia burgdorferi</i>lcsh:Biology (General)Borrelia burgdorferibiology.proteinIxodesAntibodystray dogsIFAMicroorganisms
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Determination of stilbenes in Sicilian pistachio by high-performance liquid chromatographic diode array (HPLC-DAD/FLD) and evaluation of eventually m…

2008

In this work, we have investigated about the presence of several natural stilbenes in 12 samples of pistachios harvested from 10 different farms of Sicily (Bronte and Agrigento). At the same time, we have evaluated the relation between the stilbenes synthesis and the possible contamination of mycotoxin produced by Aspergillus flavus and Aspergillus parasiticus. We have found two types of stilbenes in the samples of pistachios examined: trans-resveratrol and trans-resveratrol-3-O-β-glucoside (trans-piceid). Their concentration ranged from 0.07 to 0.18 mg/kg (av. = 0.12 ± 0.03 mg/kg) for trans-resveratrol, from 6.20 to 8.15 mg/kg (av. = 6.97 ± 0.55 mg/kg) for trans-piceid and from 6.38 to 8.2…

ChromatographybiologyAspergillus flavusGeneral MedicineContaminationbiology.organism_classificationHigh-performance liquid chromatographyDiode arrayAspergillus parasiticusAnalytical Chemistrychemistry.chemical_compoundGlucosidechemistryAnacardiaceaeMycotoxinFood ScienceFood Chemistry
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Immune response to tick-borne hemoparasites: Host adaptive immune response mechanisms as potential targets for therapies and vaccines

2020

This article belongs to the Section Molecular Immunology.

0301 basic medicineChemokine030106 microbiologyReviewAdaptive ImmunityBiologyCatalysisEpitopeInorganic Chemistry03 medical and health sciencesImmune systemAntigenmedicineAnimalsHumansCytotoxic T cellPhysical and Theoretical ChemistryAntigensMolecular BiologySpectroscopyVaccinesHost Microbial InteractionsEffectorOrganic ChemistryGeneral MedicineT helper cellAcquired immune systemTick-borne hemoparasitesComputer Science Applications030104 developmental biologymedicine.anatomical_structureAdaptive immune response Antigens Tick-borne hemoparasitesTick-Borne DiseasesImmunologybiology.proteinAdaptive immune response
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Recent Advances on the Innate Immune Response to Coxiella burnetii.

2021

Coxiella burnetii is an obligate intracellular Gram-negative bacterium and the causative agent of a worldwide zoonosis known as Q fever. The pathogen invades monocytes and macrophages, replicating within acidic phagolysosomes and evading host defenses through different immune evasion strategies that are mainly associated with the structure of its lipopolysaccharide. The main transmission routes are aerosols and ingestion of fomites from infected animals. The innate immune system provides the first host defense against the microorganism, and it is crucial to direct the infection towards a self-limiting respiratory disease or the chronic form. This review reports the advances in understanding…

Microbiology (medical)LipopolysaccharidesImmunologyexperimental modelcytokine—immunological termsQ feverimmunotherapeuticReviewMicrobiologyMicrobiologyImmune systemCellular and Infection MicrobiologyToll-like receptorinflammasomeautophagiamedicineAnimalsHumansPathogeninnate immunityInnate immune systemObligatebiologyTransmission (medicine)MacrophagesInflammasomeCoxiella burnetiibiology.organism_classificationmedicine.diseasebacterial infections and mycosesImmunity InnateQR1-502Toll-like receptorsimmunotherapeuticsInfectious DiseasesCoxiella burnetiibacteriaQ Fevercytokine—immunological termmedicine.drug
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