0000000000548656

AUTHOR

M. Nguyen-tat

showing 2 related works from this author

Comparison of computed virtual chromoendoscopy and conventional chromoendoscopy with acetic acid for detection of neoplasia in Barrett's esophagus.

2007

Background and study aims Computed virtual chromoendoscopy (CVC) is a new imaging technique that enhances mucosal surface contrast and highlights the vascular pattern without the need for dye-spraying as in conventional chromoendoscopy. The aim of this prospective randomized pilot study with a crossover design was to compare CVC with conventional chromoendoscopy with acetic acid (CAA) for the detection of high grade intraepithelial neoplasia (HGIN) or early cancer in patients with Barrett's esophagus. Patients and methods 57 patients with Barrett's esophagus (mean length 3.8 cm) and a history of HGIN/early cancer or suspected HGIN/early cancer were randomly allocated to undergo either CAA o…

AdultMalemedicine.medical_specialtyTime FactorsEsophageal NeoplasmsAdministration TopicalBiopsyGastroenterologySensitivity and SpecificitySeverity of Illness IndexEndoscopy GastrointestinalChromoendoscopyBarrett EsophagusUser-Computer InterfaceInternal medicinemedicineHumansEsophagusIntestinal MucosaAcetic AcidAgedNeoplasm StagingRetrospective StudiesAged 80 and overIntraepithelial neoplasiamedicine.diagnostic_testbusiness.industryEsophageal diseaseGastroenterologyCancerReproducibility of ResultsMiddle Agedmedicine.diseasePrognosisEndoscopymedicine.anatomical_structureBarrett's esophagusHigh Grade Intraepithelial NeoplasiaDisease ProgressionFemaleIndicators and ReagentsRadiologybusinessPrecancerous ConditionsFollow-Up StudiesEndoscopy
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"Dry biopsies" with spraying of dilute epinephrine optimize biopsy mapping of long segment Barrett's esophagus

2008

BACKGROUND AND STUDY AIMS: For surveillance of Barrett’s esophagus random stepwise four-quadrant biopsy (4QB) is recommended for detecting macroscopically occult neoplasias. Thorough performance of the systematic protocol is commonly hampered by poor visibility due to oozing from biopsy sites. Topical application of dilute epinephrine may prevent bleeding by vasoconstriction of superficial microvessels and might therefore enable ”dry biopsy” sampling. The aim of this study was to examine the safety and efficacy of spraying dilute epinephrine for optimal 4QB mapping of Barrett’s esophagus. PATIENTS AND METHODS: In this prospective, double-blind trial 40 patients with known long segment Barre…

AdultMalemedicine.medical_specialtyRandomizationEpinephrinemedicine.medical_treatmentAdministration TopicalBarrett EsophagusEsophagusDouble-Blind MethodBiopsymedicineHumansVasoconstrictor AgentsSampling (medicine)EsophagusSalineAgedAged 80 and overmedicine.diagnostic_testbusiness.industryEsophageal diseaseBiopsy NeedleGastroenterologyMiddle Agedmedicine.diseaseSurgerymedicine.anatomical_structureEpinephrineBarrett's esophagusFemaleEsophagoscopybusinessmedicine.drug
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