0000000000549841

AUTHOR

Xiaojun Yao

showing 2 related works from this author

N-Desmethyldauricine Induces Autophagic Cell Death in Apoptosis-Defective Cells via Ca2+ Mobilization

2017

Resistance of cancer cells to chemotherapy remains a significant problem in oncology. Mechanisms regulating programmed cell death, including apoptosis, autophagy or necrosis, in the treatment of cancers have been extensively investigated over the last few decades. Autophagy is now emerging as an important pathway in regulating cell death or survival in cancer therapy. Recent studies demonstrated variety of natural small-molecules could induce autophagic cell death in apoptosis-resistant cancer cells, therefore, discovery of novel autophagic enhancers from natural products could be a promising strategy for treatment of chemotherapy-resistant cancer. By computational virtual docking analysis,…

0301 basic medicinePharmacologyProgrammed cell deathautophagyKinaseDrug discoveryAutophagylcsh:RM1-950BiologyCell biology03 medical and health sciences030104 developmental biologylcsh:Therapeutics. PharmacologyApoptosisautophagic cell deathN-desmethyldauricineSERCACancer cellCytotoxic T cellPharmacology (medical)apoptosis-resistantProtein kinase AOriginal ResearchFrontiers in Pharmacology
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Prospects for quarkonium studies at the high-luminosity LHC

2020

Prospects for quarkonium-production studies accessible during the upcoming high-luminosity phases of the CERN Large Hadron Collider operation after 2021 are reviewed. Current experimental and theoretical open issues in the field are assessed together with the potential for future studies in quarkonium-related physics. This will be possible through the exploitation of the huge data samples to be collected in proton-proton, proton-nucleus and nucleus-nucleus collisions, both in the collider and fixed-target modes. Such investigations include, among others, those of: (i) J/psi and Upsilon produced in association with other hard particles; (ii) chi(c,b) and eta(c,b) down to small transverse mom…

J/psi(3100)heavy ion: scatteringgeneralized parton distributionNuclear TheoryProtonNuclear Theorynucleus nucleusparton: distribution functionPartoneta/c(3590)nucl-extransverse momentum dependenceLarge Hadron Collider (LHC)7. Clean energy01 natural sciencesHigh Energy Physics - Experimentlaw.inventionSivers functionHigh Energy Physics - Experiment (hep-ex)High Energy Physics - Phenomenology (hep-ph)lawHigh Luminosity[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]partonNuclear Experiment (nucl-ex)Quarkonium productionNuclear ExperimentNuclear Experimentquark gluon: plasmaPhysicsLarge Hadron ColliderLuminosity (scattering theory)hep-phhighnucleus nucleus: scatteringQuarkoniumheavy ionHigh Energy Physics - PhenomenologyCERN LHC CollNuclear Physics - Theoryluminosity: higheta/c(2980)Particle Physics - ExperimentquarkoniumHigh Luminosity; Large Hadron Collider (LHC); Quarkonium productionNuclear and High Energy PhysicsParticle physicsp p: scatteringsmall-xCERN Labnucl-th[PHYS.NUCL]Physics [physics]/Nuclear Theory [nucl-th]collectiveFOS: Physical sciencestransverse momentum[PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex]Nuclear Theory (nucl-th)0103 physical sciencesNuclear Physics - Experimentluminosity010306 general physicsColliderp nucleus: scatteringquark gluonplasmaParticle Physics - Phenomenology010308 nuclear & particles physicshep-exHigh Energy Physics::PhenomenologyscatteringnucleusgluonGluon[PHYS.HPHE]Physics [physics]/High Energy Physics - Phenomenology [hep-ph]Quark–gluon plasmaHigh Energy Physics::Experimentp nucleusproduction
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