0000000000550112

AUTHOR

C. Castillo-höfer

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Assessment of local cellular immunity in lung cancer by bronchoalveolar lavage.

1990

Small cell lung cancer (SCLC) is the most malignant of the pulmonary neoplasms and is associated with a poor local cellular immune response. 16 patients with non small cell lung cancer (NSCLC) and 11 patients with SCLC underwent bronchoalveolar lavage (BAL) in the lung which harbored the tumor in order to investigate the lymphocyte surface antigens utilizing the immunoperoxidase technique. Analysis of blood lymphocytes was performed in parallel. 8 patients with previous sarcoidosis in complete remission who underwent BAL and 10 normal blood donors served as controls. Among blood lymphocytes the CD3+, CD4+ and CD16+ cell populations were elevated significantly and the T4/T8 ratio was elevate…

CD4-Positive T-LymphocytesCellular immunityPathologymedicine.medical_specialtyLung NeoplasmsLymphocyteT-LymphocytesAdenocarcinomaLeukocyte CountImmune systemAntigens CDCarcinoma Non-Small-Cell LungDrug DiscoveryImmune ToleranceMedicineHumansCarcinoma Small CellLung cancerGenetics (clinical)Lungmedicine.diagnostic_testImmunoperoxidasebusiness.industryReceptors Interleukin-2General Medicinerespiratory systemmedicine.diseaserespiratory tract diseasesBronchoalveolar lavagemedicine.anatomical_structureImmunologyCarcinoma Squamous CellMolecular MedicineSarcoidosisbusinessBronchoalveolar Lavage FluidKlinische Wochenschrift
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