0000000000560611

AUTHOR

Gino Schilirò

showing 2 related works from this author

Photon scattering as a probe of microviscosity and channel size in gels such as sickle haemoglobin.

1983

The aggregation of sickle-cell haemoglobin (HbS) is one of the most physiologically important and widely studied macromolecular gelation processes. Both the thermodynamics and kinetics of the process are important in determining the pathological consequences of deoxygenation of the red cells (and both must be understood if a rational strategy is to be developed for pharmacological intervention). We describe here a new and versatile technique for the study of the structure and formation of the HbS aggregates, that should be widely applicable to gel systems generally. We use laser autocorrelation spectroscopy to observe the diffusion of monodisperse polystyrene latex spheres in the interstice…

MultidisciplinaryChemical PhenomenaScatteringChemistryChemistry PhysicalProtein ConformationViscosityDiffusionLasersKineticsDispersityHemoglobin SickleMicrospheresMicroviscosityDiffusionKineticsBiophysicsPhysical chemistryHumansScattering RadiationSpectroscopyDeoxygenationGelsMacromoleculeProtein BindingNature
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Road Traffic Pollution and Childhood Leukemia: A Nationwide Case-control Study in Italy

2016

Background The association of childhood leukemia with traffic pollution was considered in a number of studies from 1989 onwards, with results not entirely consistent and little information regarding subtypes. Aim of the study We used the data of the Italian SETIL case-control on childhood leukemia to explore the risk by leukemia subtypes associated to exposure to vehicular traffic. Methods We included in the analyses 648 cases of childhood leukemia (565 Acute lymphoblastic–ALL and 80 Acute non lymphoblastic-AnLL) and 980 controls. Information on traffic exposure was collected from questionnaire interviews and from the geocoding of house addresses, for all periods of life of the children. Re…

MyeloidMaleFuture studies010501 environmental sciencesSettore MED/42 - Igiene Generale E Applicata01 natural sciences0302 clinical medicineEconomicahemic and lymphatic diseasesMedicine030212 general & internal medicineChildRoad trafficacute non lymphoblastic leukemia; childhood; environment; leukemia; road traffic; air pollution; case-control studies; child; child preschool; female; humans; infant; Italy; leukemia myeloid acute; male; precursor cell lymphoblastic leukemia-lymphoma; risk; motor vehicles; medicine (all)LeukemiaTraffic pollutionMedicine (all)General MedicinePrecursor Cell Lymphoblastic Leukemia-LymphomaLeukemiaMotor VehiclesLeukemia Myeloid AcuteItalyAcute non Lymphoblastic LeukemiaSettore MED/38 - PEDIATRIA GENERALE E SPECIALISTICARoad TrafficChild PreschoolFemaleMedical emergencyCase-Control StudieHumanRiskChildhood leukemiaSocio-culturaleAcuteEnvironmentPrecursor Cell Lymphoblastic Leukemia Lymphoma03 medical and health sciencesEnvironmental healthAir PollutionHumansPreschool0105 earth and related environmental sciencesbusiness.industryCase-control studyType specificAmbientaleInfantmedicine.diseaseChildhoodCase-Control StudiesMotor Vehiclebusiness
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