0000000000562001
AUTHOR
Jānis Eglītis
Tautas nobalsošanas un to iespaids uz iedzīvotāju uzticēšanos demokrātiskām institūcijām Latvijā
Viena no liberālo demokrātiju iezīmēm ir sabiedrības neuzticēšanās, vilšanās un atsvešināšanās no politikas. Lai situāciju uzlabotos, valstij esot jānodrošina, ka cilvēki ar tiešās demokrātijas procedūru palīdzību vairāk līdzdarbojas politikā. Darbā pētu kā tiešā demokrātija Latvijā ietekmē iedzīvotāju uzticēšanos valsts pārvaldei. Darba gaitā tika veikts teorētisks un empīrisks pētījums. Analizēts tiešās demokrātijas blakus efekti, un tiešās demokrātijas regulējums un prakse Latvijā. Tiek secināts,ka referendumu augošā popularitāte ir saistīta ar sabiedrības pieaugošo cinismu un neapmierinātību ar valsts pārvaldi un „viltus populismu” no politiskās elites grupējumiem. Lai arī vēlētāju iesa…
Heavy Resistance Training in Breast Cancer Patients Undergoing Adjuvant Therapy.
BACKGROUND AND PURPOSE Adjuvant breast cancer therapy may reduce maximal muscle strength, muscle mass, and functional performance. Although maximal strength training (MST) has the potential to counteract this debilitating outcome and is shown to be superior to low- and moderate-intensity strength training, it is unknown if it can elicit effective adaptations in patients suffering treatment-induced adverse side effects. METHODS Fifty-five newly diagnosed stage I to III breast cancer patients (49 ± 7 yr) scheduled for adjuvant therapy were randomized to MST or a control group. The MST group performed 4 × 4 repetitions of dynamic leg press at approximately 90% of one-repetition maximum (1RM) t…
CD63 and Dna Mismatch Repair Protein Expression in Prostate Cancer
Abstract Protein expression levels in immunohistochemistry and molecular biomarkers have been reported for their ability to predict recurrence, progression, development of metastases, and patient survival. The molecular features in low- and high-grade prostate cancer can differ and influence treatment decision and prognosis. The objective of the current study was to compare the expression of exosomal biomarkers CD63 and mismatch repair proteins (MSH2, MSH6, MLH1, and PMS2) by immunohistochemistry (IHC) in tissue of patients with prostate cancer and benign hyperplasia. Altogether, 62 patients with prostate acinar adenocarcinoma and 20 patients with prostate benign hyperplasia were enrolled i…