0000000000574649

AUTHOR

S. Bolognesi

showing 33 related works from this author

Study of scintillation light collection, production and propagation in a 4 tonne dual-phase LArTPC

2020

The $3 \times 1 \times 1$ m$^3$ demonstrator is a dual phase liquid argon time projection chamber that has recorded cosmic rays events in 2017 at CERN. The light signal in these detectors is crucial to provide precise timing capabilities. The performances of the photon detection system, composed of five PMTs, are discussed. The collected scintillation and electroluminescence light created by passing particles has been studied in various detector conditions. In particular, the scintillation light production and propagation processes have been analyzed and compared to simulations, improving the understanding of some liquid argon properties.

photon: propagationPhotomultiplierCERN LabPhysics - Instrumentation and DetectorsPhysics::Instrumentation and DetectorstutkimuslaitteetPerformance of High Energy Physics DetectorPhase (waves)FOS: Physical sciencesCosmic rayNoble liquid detectors (scintillation ionization double-phase)Scintillator01 natural sciences7. Clean energyHigh Energy Physics - ExperimentHigh Energy Physics - Experiment (hep-ex)Optics0103 physical sciences[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex][PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det]Detectors and Experimental Techniques010306 general physicsInstrumentationphysics.ins-detMathematical Physicsscintillation counterPhysicsScintillationTime projection chamberphotomultiplier010308 nuclear & particles physicsbusiness.industryhep-exDetectorScintillators scintillation and light emission processes (solid gas and liquid scintillators)Instrumentation and Detectors (physics.ins-det)time projection chamber: liquid argonNoble liquid detectors (scintillation ionization double-phase); Performance of High Energy Physics Detectors; Photon detectors for UV visible and IR photons (vacuum) (photomulti-pliers HPDs others); Scintillators scintillation and light emission processes (solid gas and liquidscintillators)Photon detectors for UV visible and IR photons (vacuum) (photomultipliers HPDs others)FIS/01 - FISICA SPERIMENTALEilmaisimetScintillation counterbusinesskosminen säteilyperformanceParticle Physics - Experiment
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Measurement of Coherent π+ Production in Low Energy Neutrino-Carbon Scattering

2016

We report the first measurement of the flux-averaged cross section for charged current coherent π+ production on carbon for neutrino energies less than 1.5 GeV, and with a restriction on the final state phase space volume in the T2K near detector, ND280. Comparisons are made with predictions from the Rein-Sehgal coherent production model and the model by Alvarez-Ruso et al., the latter representing the first implementation of an instance of the new class of microscopic coherent models in a neutrino interaction Monte Carlo event generator. We observe a clear event excess above background, disagreeing with the null results reported by K2K and SciBooNE in a similar neutrino energy region. The …

Physics010308 nuclear & particles physicsScatteringMonte Carlo methodDetectorGeneral Physics and Astronomy7. Clean energy01 natural sciencesNuclear physicsLow energyPhase space0103 physical sciencesHigh Energy Physics::ExperimentNeutrino010306 general physicsCharged currentEvent generatorPhysical Review Letters
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Search for short baseline nu(e) disappearance with the T2K near detector

2015

8 pages.- 6 figures

Nuclear and High Energy PhysicsParticle physicsSterile neutrinoAstronomy & AstrophysicsNeutrino beam7. Clean energy01 natural sciencesHigh Energy Physics - ExperimentPhysics Particles & FieldsNuclear physics0202 Atomic Molecular Nuclear Particle And Plasma Physics0103 physical sciences[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]010306 general physicsNeutrino oscillation0206 Quantum PhysicsNeutrino fluxPhysicsScience & Technologyhep-ex010308 nuclear & particles physicsPhysicsDetectorT2K experimentNuclear & Particles Physics0201 Astronomical And Space SciencesPhysical Sciences
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Volume IV The DUNE far detector single-phase technology

2020

This document was prepared by the DUNE collaboration using the resources of the Fermi National Accelerator Laboratory (Fermilab), a U.S. Department of Energy, Office of Science, HEP User Facility. Fermilab is managed by Fermi Research Alliance, LLC (FRA), acting under Contract No. DE-AC02-07CH11359. The DUNE collaboration also acknowledges the international, national, and regional funding agencies supporting the institutions who have contributed to completing this Technical Design Report.

Technology530 Physicsmedia_common.quotation_subjectNeutrino oscillations liquid Argon TPC DUNE technical design report single phase LArTPCElectronsFREE-ELECTRONS01 natural sciences7. Clean energy09 Engineering030218 nuclear medicine & medical imagingStandard Model03 medical and health sciencesneutrino0302 clinical medicineLIQUID ARGON0103 physical sciencesGrand Unified TheoryHigh Energy PhysicsAerospace engineeringInstrumentationInstruments & InstrumentationMathematical Physicsmedia_commonPhysicsScience & Technology02 Physical Sciences010308 nuclear & particles physicsbusiness.industryDetectorLıquıd ArgonfreeNuclear & Particles PhysicsSymmetry (physics)UniverseLong baseline neutrino experiment CP violationAntimatterNeutrinobusinessEvent (particle physics)
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First results on ProtoDUNE-SP liquid argon time projection chamber performance from a beam test at the CERN Neutrino Platform

2020

The ProtoDUNE-SP detector was constructed and operated on the CERN Neutrino Platform. We thank the CERN management for providing the infrastructure for this experiment and gratefully acknowledge the support of the CERN EP, BE, TE, EN, IT and IPT Departments for NP04/ProtoDUNE-SP. This documentwas prepared by theDUNEcollaboration using the resources of the Fermi National Accelerator Laboratory (Fermilab), a U.S. Department of Energy, Office of Science, HEP User Facility. Fermilab is managed by Fermi Research Alliance, LLC (FRA), acting under Contract No. DE-AC02-07CH11359. This work was supported by CNPq, FAPERJ, FAPEG and FAPESP, Brazil; CFI, IPP and NSERC, Canada; CERN; MSMT, Czech Republi…

TechnologyHIGH-ENERGYPhysics - Instrumentation and DetectorsPhysics::Instrumentation and Detectorsfar detectorbeam transportNoble liquid detectors (scintillation ionization double-phase)Cms Experıment01 natural sciences7. Clean energy09 EngineeringParticle identificationHigh Energy Physics - Experiment030218 nuclear medicine & medical imagingHigh Energy Physics - Experiment (hep-ex)0302 clinical medicineNoble liquid detectors (scintillationDetectors and Experimental TechniquesInstrumentationInstruments & Instrumentationphysics.ins-dettime resolutionMathematical PhysicsPhysics02 Physical SciencesTime projection chamberLarge Hadron ColliderDetectorInstrumentation and Detectors (physics.ins-det)double-phase)Nuclear & Particles PhysicsLIGHTNeutrinoParticle Physics - ExperimentperformanceNoble liquid detectors(scintillation ionization double-phase)noiseCERN LabLarge detector systems for particle and astroparticle physics Noble liquid detectors (scintillation ionization double-phase) Time projection Chambers (TPC)530 Physicsenergy lossTime projection chambersFOS: Physical sciencesParticle detectorNuclear physics03 medical and health sciencesneutrino: deep underground detector0103 physical sciencesionizationDeep Underground Neutrino ExperimentHigh Energy Physics[PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det]signal processingactivity reportScience & Technology010308 nuclear & particles physicshep-exLarge detector systems for particle and astroparticle physicsTime projection Chambers (TPC)530 Physiksensitivitycalibrationtime projection chamber: liquid argonExperimental High Energy PhysicsLarge detector systems for particle and astroparticle physicsingle-phase)Large detector systems for particle and astroparticle physics; Noble liquid detectors (scintillation ionization double-phase); Time projection Chambers (TPC)High Energy Physics::Experimentphoton: detectorparticle identificationcharged particle: irradiationBeam (structure)
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Neutrino interaction classification with a convolutional neural network in the DUNE far detector

2020

The Deep Underground Neutrino Experiment is a next-generation neutrino oscillation experiment that aims to measure CP-violation in the neutrino sector as part of a wider physics program. A deep learning approach based on a convolutional neural network has been developed to provide highly efficient and pure selections of electron neutrino and muon neutrino charged-current interactions. The electron neutrino (antineutrino) selection efficiency peaks at 90% (94%) and exceeds 85% (90%) for reconstructed neutrino energies between 2–5 GeV. The muon neutrino (antineutrino) event selection is found to have a maximum efficiency of 96% (97%) and exceeds 90% (95%) efficiency for reconstructed neutrino…

Neutrino Oscillations. Neutrino detectors.Physics - Instrumentation and DetectorsPhysics::Instrumentation and Detectorsfar detector01 natural sciencesPhysics Particles & FieldsHigh Energy Physics - Experimentcharged currentHigh Energy Physics - Experiment (hep-ex)[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]Particle Physics ExperimentsMuon neutrinoneutrino/e: particle identificationNeutrino detectorsDetectors and Experimental Techniquesphysics.ins-detCharged currentneutrino: interactionInformáticaPhysicsTelecomunicacionesNeutrino oscillationsPhysicsNeutrino interactions neural network DUNE Deep Underground Neutrino ExperimentInstrumentation and Detectors (physics.ins-det)Experiment (hep-ex)Neutrino detectorPhysical SciencesCP violationNeutrinoParticle Physics - ExperimentParticle physicsdata analysis method530 Physicsneural networkAstrophysics::High Energy Astrophysical PhenomenaCONSERVATIONFOS: Physical sciencesAstronomy & AstrophysicsDeep Learningneutrino: deep underground detectorneutrino physics0103 physical sciencesNeutrino Oscillations. Neutrino detectorsObject DetectionNeutrinoCP: violationDeep Underground Neutrino ExperimentHigh Energy Physics[PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det]Neutrinos010306 general physicsNeutrino oscillationneutrino/mu: particle identificationIOUScience & TechnologyDUNENeutrino interactions010308 nuclear & particles physicshep-exHigh Energy Physics::PhenomenologyFísicaNeutrino InteractionDetector530 PhysiksensitivityefficiencyHigh Energy Physics::ExperimentElectron neutrino
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Combined Analysis of Neutrino and Antineutrino Oscillations at T2K.

2017

T2K reports its first results in the search for CP violation in neutrino oscillations using appearance and disappearance channels for neutrino- and antineutrino-mode beams. The data include all runs from January 2010 to May 2016 and comprise 7.482 ×10^(20) protons on target in neutrino mode, which yielded in the far detector 32 e-like and 135 μ-like events, and 7.471 × 10^(20) protons on target in antineutrino mode, which yielded 4 e-like and 66 μ-like events. Reactor measurements of sin(2)2θ(13) have been used as an additional constraint. The one-dimensional confidence interval at 90% for the phase δCP spans the range (−3.13, −0.39) for normal mass ordering. The CP conservation hypothesis …

Particle physicsGeneral PhysicsNeutrino oscillations; CP violation; Neutrino detectors530 PhysicsPhysics MultidisciplinaryFOS: Physical sciencesGeneral Physics and Astronomy01 natural sciences7. Clean energy09 EngineeringHigh Energy Physics - ExperimentNuclear physicsHigh Energy Physics - Experiment (hep-ex)Physics and Astronomy (all)0103 physical sciences[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]Neutrino detectors010306 general physicsNeutrino oscillationGeneralLiterature_REFERENCE(e.g.dictionariesencyclopediasglossaries)01 Mathematical SciencesComputingMilieux_MISCELLANEOUSQCPhysicsScience & Technology02 Physical Sciences010308 nuclear & particles physicshep-exNeutrino oscillationsPhysicsCP violationNeutrino detectorantineutrino oscillationsT2K CollaborationPhysical SciencesCP violationNeutrinoPhysical review letters
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Search for Electron Antineutrino Appearance in a Long-baseline Muon Antineutrino Beam

2020

Electron antineutrino appearance is measured by the T2K experiment in an accelerator-produced antineutrino beam, using additional neutrino beam operation to constrain parameters of the Pontecorvo-Maki-Nakagawa-Sakata (PMNS) mixing matrix. T2K observes 15 candidate electron antineutrino events with a background expectation of 9.3 events. Including information from the kinematic distribution of observed events, the hypothesis of no electron antineutrino appearance is disfavored with a significance of 2.40 σ and no discrepancy between data and PMNS predictions is found. A complementary analysis that introduces an additional free parameter which allows non-PMNS values of electron neutrino and a…

muon antineutrino beamGeneral Physics and Astronomyantineutrino/mu: secondary beamKAMIOKANDEantineutrino/e: particle identification01 natural sciences09 EngineeringHigh Energy Physics - ExperimentHigh Energy Physics - Experiment (hep-ex)secondary beam [neutrino/mu][PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]neutrino/e: particle identificationQCPhysics02 Physical SciencesPhysicsJ-PARC LabT2K experimentelectron antineutrinoT2K CollaborationkinematicsPhysical SciencesParticle Physics - ExperimentT2K experiment in an accelerator-producedGeneral Physics530 PhysicsPhysics MultidisciplinaryFOS: Physical sciencesparticle identification [antineutrino/e]Neutrino beamsecondary beam [antineutrino/mu]530Physics::GeophysicsNuclear physics0103 physical sciencesmixingddc:530010306 general physics01 Mathematical SciencesMuonScience & Technologyparticle identification [neutrino/e]hep-exbackgroundHigh Energy Physics - Experiment; High Energy Physics - Experimentneutrino/mu: secondary beamantineutrino: oscillationoscillation [antineutrino]Elementary Particles and FieldsHigh Energy Physics::ExperimentPMNSElectron neutrinoBeam (structure)Free parameterexperimental results
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Measurements of ν̅ μ and ν̅ μ + ν μ charged-current cross-sections without detected pions or protons on water and hydrocarbon at a mean anti-neutrino…

2021

Abstract We report measurements of the flux-integrated ν̅μ and ν̅μ + νμ charged-current cross-sections on water and hydrocarbon targets using the T2K anti-neutrino beam with a mean beam energy of 0.86 GeV. The signal is defined as the (anti-)neutrino charged-current interaction with one induced $\mu^\pm$ and no detected charged pion or proton. These measurements are performed using a new WAGASCI module recently added to the T2K setup in combination with the INGRID Proton Module. The phase space of muons is restricted to the high-detection efficiency region, $p_{\mu}>400~{\rm MeV}/c$ and $\theta_{\mu}<30^{\circ}$, in the laboratory frame. An absence of pions and protons in the …

chemistry.chemical_classificationPhysicsParticle physicsMuonProton010308 nuclear & particles physicsGeneral Physics and Astronomy01 natural sciencesHydrocarbonPionchemistry0103 physical sciences010306 general physicsNucleonEnergy (signal processing)Charged currentBar (unit)Progress of Theoretical and Experimental Physics
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First T2K measurement of transverse kinematic imbalance in the muon-neutrino charged-current single- π+ production channel containing at least one pr…

2021

This paper reports the first T2K measurement of the transverse kinematic imbalance in the single-$\pi^+$ production channel of neutrino interactions. We measure the differential cross sections in the muon-neutrino charged-current interaction on hydrocarbon with a single $\pi^+$ and at least one proton in the final state, at the ND280 off-axis near detector of the T2K experiment. The extracted cross sections are compared to the predictions from different neutrino-nucleus interaction event generators. Overall, the results show a preference for models which have a more realistic treatment of nuclear medium effects including the initial nuclear state and final-state interactions.

PhysicsProtonPhysics::Instrumentation and Detectors010308 nuclear & particles physicsMonte Carlo methodT2K experiment01 natural sciences7. Clean energyNuclear physicsTransverse plane0103 physical sciencesMuon neutrinoNeutrino010306 general physicsEvent (particle physics)Charged currentPhysical Review D
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Measurement of the muon neutrino inclusive charged-current cross section in the energy range of 1–3 GeV with the T2K INGRID detector

2016

International audience; We report a measurement of the $\nu_{\mu}$-nucleus inclusive charged current cross section (=$\sigma^{cc}$) on iron using data from exposed to the J-PARC neutrino beam. The detector consists of 14 modules in total, which are spread over a range of off-axis angles from 0$^\circ$ to 1.1$^\circ$. The variation in the neutrino energy spectrum as a function of the off-axis angle, combined with event topology information, is used to calculate this cross section as a function of neutrino energy. The cross section is measured to be $\sigma^{cc}(1.1\text{ GeV}) = 1.10 \pm 0.15$ $(10^{-38}\text{cm}^2/\text{nucleon})$, $\sigma^{cc}(2.0\text{ GeV}) = 2.07 \pm 0.27$ $(10^{-38}\te…

COLLISIONSNuclear and High Energy PhysicsParticle physicsMULTIPLICITY DISTRIBUTIONSPhysics::Instrumentation and Detectors530 PhysicsFOS: Physical sciencesneutrino scatteringAstronomy & Astrophysics01 natural sciences7. Clean energyHigh Energy Physics - ExperimentPhysics Particles & FieldsNuclear physicsHigh Energy Physics - Experiment (hep-ex)Cross section (physics)0202 Atomic Molecular Nuclear Particle And Plasma PhysicsMONTE-CARLO0103 physical sciencesPION ABSORPTION[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]Muon neutrino010306 general physicsNuclear Experiment0206 Quantum PhysicsCharged currentPhysicsRange (particle radiation)Science & TechnologyNUCLEIhep-ex010308 nuclear & particles physicsPhysicsneutrinoscross sectionsNuclear & Particles Physics0201 Astronomical And Space SciencesPhysical SciencesSIMULATIONHigh Energy Physics::ExperimentNeutrinoNucleonEvent (particle physics)Energy (signal processing)
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Search for heavy neutrinos with the T2K near detector ND280

2019

This paper reports on the search for heavy neutrinos with masses in the range 140<MN<493  MeV/c2 using the off-axis near detector ND280 of the T2K experiment. These particles can be produced from kaon decays in the standard neutrino beam and then subsequently decay in ND280. The decay modes under consideration are N→ℓ±απ∓ and N→ℓ+αℓ−β(−)ν(α,β=e,μ). A search for such events has been made using the Time Projection Chambers of ND280, where the background has been reduced to less than two events in the current dataset in all channels. No excess has been observed in the signal region. A combined Bayesian statistical approach has been applied to extract upper limits on the mixing elements of heav…

decay modes [neutrino]GENERAL-THEORYmixing [neutrino]Physics::Instrumentation and Detectorsneutrino: heavy: search forKAMIOKANDE01 natural sciencesHigh Energy Physics - ExperimentPhysics Particles & FieldsHigh Energy Physics - Experiment (hep-ex)LIMITSsecondary beam [neutrino/mu]neutrino: decay modes[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]Particle Physics Experimentsneutrino: massmedia_commonPhysicsVMSMJ-PARC LabPhysicsstatistical analysis: BayesianK: decayheavy neutrinos T2K Experiment Time Projection Chambersmass dependenceGeneral theoryT2K ExperimentTime Projection ChambersPhysical SciencesChristian ministrydata analysis methodFOS: Physical sciencesLibrary scienceheavy: search for [neutrino]Astronomy & AstrophysicsBayesian [statistical analysis]530near detector0103 physical sciencesDARK-MATTERmedia_common.cataloged_instanceddc:530Early careerEuropean unionS077A00010306 general physicsS077A01heavy neutrinosScience & Technology010308 nuclear & particles physicsbackgroundhep-exHigh Energy Physics::PhenomenologyFísicaneutrino/mu: secondary beamtime projection chamberdecay [K]mass [neutrino]Hypothetical particle physics models Particle phenomenaHigh Energy Physics::Experimentneutrino: mixingstatisticalexperimental resultsPhysical Review D
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Updated T2K measurements of muon neutrino and antineutrino disappearance using 1.5×1021 protons on target

2017

We report measurements by the T2K experiment of the parameters $\theta_{23}$ and $\Delta m^{2}_{32}$ governing the disappearance of muon neutrinos and antineutrinos in the three flavor neutrino oscillation model. Utilizing the ability of the experiment to run with either a mainly neutrino or a mainly antineutrino beam, the parameters are measured separately for neutrinos and antineutrinos. Using $7.482 \times 10^{20}$ POT in neutrino running mode and $7.471 \times 10^{20}$ POT in antineutrino mode, T2K obtained, $\sin^{2}(\theta_{23})=0.51^{+0.08}_{-0.07}$ and $\Delta m^{2}_{32} = 2.53^{+0.15}_{-0.13} \times 10^{-3}$eV$^{2}$/c$^{4}$ for neutrinos, and $\sin^{2}({\overline{\theta}}_{23})=0.4…

PhysicsNuclear physicsParticle physicsMuon010308 nuclear & particles physics0103 physical sciencesT2K experimentMuon neutrinoNeutrino010306 general physicsNeutrino oscillation7. Clean energy01 natural sciencesPhysical Review D
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Measurement of the $\nu_{\mu}$ charged current quasi-elastic cross-section on carbon with the T2K on-axis neutrino beam

2015

17 pages.- 21 figures

Particle physicsNuclear and High Energy Physicschemistry.chemical_elementPion productionAstronomy & AstrophysicsMASSNeutrino beamPION-PRODUCTION7. Clean energy01 natural sciencesPhysics Particles & FieldsHigh Energy Physics - ExperimentNuclear physicsScatteringCross section (physics)0202 Atomic Molecular Nuclear Particle And Plasma Physics0103 physical sciences[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]Neutron010306 general physicsNeutrino oscillationNuclear Experiment0206 Quantum PhysicsCharged currentPhysicsScience & Technologyhep-ex010308 nuclear & particles physicsScatteringPhysicsDetectorNuclear & Particles PhysicsMODEL0201 Astronomical And Space ScienceschemistryPhysical SciencesHigh Energy Physics::ExperimentNeutrinoCarbonNuclear targets
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Measurement of double-differential muon neutrino charged-current interactions onC8H8without pions in the final state using the T2K off-axis beam

2016

We report the measurement of muon neutrino charged-current interactions on carbon without pions in the final state at the T2K beam energy using 5.734×1020 protons on target. For the first time the measurement is reported as a flux-integrated, double-differential cross section in muon kinematic variables (cosθμ, pμ), without correcting for events where a pion is produced and then absorbed by final state interactions. Two analyses are performed with different selections, background evaluations and cross-section extraction methods to demonstrate the robustness of the results against biases due to model-dependent assumptions. The measurements compare favorably with recent models which include n…

PhysicsParticle physicsMuon010308 nuclear & particles physicsMonte Carlo method01 natural sciences7. Clean energyNuclear physicsCross section (physics)PionPhase space0103 physical sciencesHigh Energy Physics::ExperimentMuon neutrinoNuclear Experiment010306 general physicsBeam (structure)Charged currentPhysical Review D
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Search for Lorentz and CPT violation using sidereal time dependence of neutrino flavor transitions over a short baseline

2017

A class of extensions of the Standard Model allows Lorentz and CPT violations, which can be identified by the observation of sidereal modulations in the neutrino interaction rate. A search for such modulations was performed using the T2K on-axis near detector. Two complementary methods were used in this study, both of which resulted in no evidence of a signal. Limits on associated Lorentz and CPT-violating terms from the Standard Model extension have been derived by taking into account their correlations in this model for the first time. These results imply such symmetry violations are suppressed by a factor of more than 1020 at the GeV scale.

Physics and Astronomy (miscellaneous)CPT symmetryAstrophysicsKAMIOKANDE01 natural scienceshigh energy physicsPhysics Particles & FieldsHigh Energy Physics - ExperimentHigh Energy Physics - Experiment (hep-ex)Standard-Model Extension[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]neutrino: interactionPhysicssymmetry: violationPhysicsJ-PARC LabCPT symmetrysuppressionLorentz symmetryviolation: LorentzmodulationSidereal timePhysical Sciencesneutrino: flavorsymbolsNeutrinoupper limitParticle physicsdata analysis method530 PhysicsLorentz transformationFOS: Physical sciencesCPT: violationAstronomy & AstrophysicsStandard Modelsymbols.namesakenear detectorstatistical analysis0103 physical sciences010306 general physicsNeutrino oscillationneutrino oscillationsScience & Technology010308 nuclear & particles physicshep-exHigh Energy Physics::PhenomenologySymmetry (physics)neutrino/mu: secondary beamcorrelationtime dependenceHigh Energy Physics::Experimentneutrino: oscillationexperimental results
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A 4 tonne demonstrator for large-scale dual-phase liquid argon time projection chambers

2018

A 10 kilo-tonne dual-phase liquid argon TPC is one of the detector options considered for the Deep Underground Neutrino Experiment (DUNE). The detector technology relies on amplification of the ionisation charge in ultra-pure argon vapour and offers several advantages compared to the traditional single-phase liquid argon TPCs. A 4.2 tonne dual-phase liquid argon TPC prototype, the largest of its kind, with an active volume of \three has been constructed and operated at CERN. In this paper we describe in detail the experimental setup and detector components as well as report on the operation experience. We also present the first results on the achieved charge amplification, prompt scintillat…

Physics - Instrumentation and DetectorsPhysics::Instrumentation and Detectorshiukkasfysiikka01 natural sciences7. Clean energyHigh Energy Physics - ExperimentNeutrino detectorHigh Energy Physics - Experiment (hep-ex)Ionization[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]Neutrino detectorsDetectors and Experimental TechniquesNuclear ExperimentInstrumentationphysics.ins-detMathematical Physicsgas: admixtureLarge Hadron ColliderDetectorneutriinotInstrumentation and Detectors (physics.ins-det)experimental equipmentneutrino: detectorNeutrino detectorTime projection chamberilmaisimettime projection chambersLarge scale cryogenic liquid detectors [8]photon: yieldParticle Physics - ExperimentperformanceMaterials scienceCERN LabTime projection chambersParticle tracking detectors (Gaseous detectors)ionization: yieldparticle tracking detectors (gaseous detectors)tutkimuslaitteetFOS: Physical scienceschemistry.chemical_elementNeutrino detectors; Particle tracking detectors (Gaseous detectors); Time projection chambersOptics0103 physical sciencesDeep Underground Neutrino Experiment[PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det]010306 general physicsScintillationArgon010308 nuclear & particles physicsbusiness.industryhep-extime projection chamber: liquid argonchemistrymuon: cosmic radiationHigh Energy Physics::ExperimentbusinessTonneneutrino detectors
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Volume I. Introduction to DUNE

2020

Journal of Instrumentation 15(08), T08008 (1-228) (2020). doi:10.1088/1748-0221/15/08/T08008

detector: technologydeep underground detector [neutrino]530 PhysicsPhysics::Instrumentation and DetectorsData managementmedia_common.quotation_subjectfar detector610Long baseline neutrino experiment CP violation01 natural sciences030218 nuclear medicine & medical imagingNeutrino oscillations. Neutrino Detectors. CP violation. Matter stabilitydesign [detector]03 medical and health sciencesneutrinoneutrino: deep underground detector0302 clinical medicinenear detector0103 physical sciencesDeep Underground Neutrino Experimentddc:610Neutrino oscillationInstrumentationdetector: designMathematical Physicsactivity reportmedia_common010308 nuclear & particles physicsbusiness.industryNeutrino oscillations. Neutrino Detectors. CP violation. Matter stability.DetectorVolume (computing)Modular designtime projection chamber: liquid argonUniversetechnology [detector]liquid argon [time projection chamber]Systems engineeringHigh Energy Physics::ExperimentNeutrino oscillations DUNE technical design report executive summary detector technologiesdata managementNeutrinobusiness
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Search forBs0→μ+μ−andB0→μ+μ−Decays with CDF II

2011

A search has been performed for B{sub s}{sup 0} {yields} {mu}{sup +}{mu}{sup -} and B{sup 0} {yields} {mu}{sup +}{mu}{sup -} decays using 7 fb{sup -1} of integrated luminosity collected by the CDF II detector at the Fermilab Tevatron collider. The observed number of B{sup 0} candidates is consistent with background-only expectations and yields an upper limit on the branching fraction of {Beta}(B{sup 0} {yields} {mu}{sup +}{mu}{sup -}) < 6.0 x 10{sup -9} at 95% confidence level. We observe an excess of B{sub s}{sup 0} candidates. The probability that the background processes alone could produce such an excess or larger is 0.27%. The probability that the combination of background and the expe…

Flight directionNuclear and High Energy PhysicsParticle physicsMesonTevatronGeneral Physics and Astronomy01 natural sciences7. Clean energyLuminosityStandard Modellaw.inventionNuclear physicsParticle decaychemistry.chemical_compoundlawTheoryofComputation_ANALYSISOFALGORITHMSANDPROBLEMCOMPLEXITY0103 physical sciencesInvariant massLimit (mathematics)FermilabCollider010306 general physicsPhysicsMuon010308 nuclear & particles physicsBranching fractionSupersymmetryD0 experimentIMesCrystallographychemistryDecay lengthHigh Energy Physics::ExperimentLeptonPhysical Review Letters
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Characterization of nuclear effects in muon-neutrino scattering on hydrocarbon with a measurement of final-state kinematics and correlations in charg…

2018

This paper reports measurements of final-state proton multiplicity, muon and proton kinematics, and their correlations in charged-current pionless neutrino interactions, measured by the T2K ND280 near detector in its plastic scintillator (C$_8$H$_8$) target. The data were taken between years 2010 and 2013, corresponding to approximately 6$\times10^{20}$ protons on target. Thanks to their exploration of the proton kinematics and of kinematic imbalances between the proton and muon kinematics, the results offer a novel probe of the nuclear-medium effects most pertinent to the (sub-)GeV neutrino-nucleus interactions that are used in accelerator-based long-baseline neutrino oscillation measureme…

Fermi gasProtoninteraction: modelPhysics and Astronomy (miscellaneous)Physics::Instrumentation and DetectorsKinematicsKAMIOKANDE7. Clean energy01 natural sciencesPhysics Particles & Fieldscharged currentHigh Energy Physics - ExperimentHigh Energy Physics - Experiment (hep-ex)[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]Particle Physics ExperimentsMuon neutrinoneutrino oscillationAXISNuclear ExperimentHigh Energy Physics - Experiment; High Energy Physics - Experiment; Physics and Astronomy (miscellaneous)Charged currentneutrino: interactionPhysicsCHALLENGESPhysicsJ-PARC Labp: final state3. Good healthtransversekinematicsPhysical SciencesNeutrinospectral representationFOS: Physical sciencesddc:500.2Astronomy & AstrophysicsREGIONNuclear physicsphase spacenear detectormuon0103 physical sciencesEXCITATIONddc:530010306 general physicsNeutrino oscillationDETECTORnuclear matter effectscintillation counterp: multiplicityMuonScience & Technology010308 nuclear & particles physicshep-exnucleusscatteringnuclear matter: effectneutrino nucleus: interactionfinal-state interactionneutrino/mu: secondary beamPhase spacecorrelationPhysics::Accelerator Physicsneutrino nucleus interactionneutrino: oscillationexperimental results
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Measurement of theνμcharged-current quasielastic cross section on carbon with the ND280 detector at T2K

2015

We thank the J-PARC staff for superb accelerator performance and the CERN NA61 Collaboration for providing valuable particle production data. We acknowledge the support of MEXT, Japan; NSERC, NRC, and CFI, Canada; CEA and CNRS/IN2P3, France; DFG, Germany; INFN, Italy; National Science Centre (NCN), Poland; RSF, RFBR, and MES, Russia; MINECO and ERDF funds, Spain; SNSF and SER, Switzerland; STFC, UK; and DOE, USA. We also thank CERN for the UA1/NOMAD magnet, DESY for the HERA-B magnet mover system, NII for SINET4, the WestGrid and SciNet consortia in Compute Canada, GridPP, UK. In addition participation of individual researchers and institutions has been further supported by funds from ERC (…

PhysicsNuclear physicsNuclear and High Energy Physics010308 nuclear & particles physics0103 physical sciencesLibrary scienceDESYEarly career010306 general physics7. Clean energy01 natural sciencesNeutrino scatteringPhysical Review D
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Measurement of thett¯production cross section inpp¯collisions ats=1.96  TeVusing soft electronb-tagging

2010

The authors present a measurement of the t{bar t} production cross section using events with one charged lepton and jets from p{bar p} collisions at a center-of-mass energy of 1.96 TeV. A b-tagging algorithm based on the probability of displaced tracks coming from the event interaction vertex is applied to identify b quarks from top decay. Using 318 pb{sup -1} of data collected with the CDF II detector, they measure the t{bar t} production cross section in events with at least one restrictive (tight) b-tagged jet and obtain 8.9{sub -1.0}{sup +1.0}(stat.){sub -1.0}{sup +1.1}(syst.) pb. The cross section value assumes a top quark mass of m{sub t} is presented in the paper. This result is cons…

Top quarkCollider physicsHadronTevatronGeneral Physics and AstronomyElementary particleKinematicsElectronJet (particle physics)01 natural sciences7. Clean energyParticle identificationlaw.inventionlawInvariant massFermilabNuclear ExperimentQuantum chromodynamicsPhysicsLarge Hadron ColliderLuminosity (scattering theory)Supersymmetryb-taggingHadronizationTransverse planeProduction (computer science)Collider Detector at FermilabQuarkSemileptonic decayNuclear and High Energy PhysicsParticle physicsBar (music)Astrophysics::High Energy Astrophysical PhenomenaBottom quarkMeasure (mathematics)Standard ModelNuclear physicsCross section (physics)Particle decay0103 physical sciencesCollider010306 general physicsCompact Muon SolenoidMuonBranching fraction010308 nuclear & particles physicsHigh Energy Physics::PhenomenologyMultiplicity (mathematics)FermionVertex (geometry)Pair productionHigh Energy Physics::ExperimentEnergy (signal processing)Bar (unit)LeptonPhysical Review D
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Search for CP Violation in Neutrino and Antineutrino Oscillations by the T2K Experiment with 2.2×1021 Protons on Target

2018

The T2K experiment measures muon neutrino disappearance and electron neutrino appearance in accelerator-produced neutrino and antineutrino beams. With an exposure of $14.7(7.6)\times 10^{20}$ protons on target in neutrino (antineutrino) mode, 89 $\nu_e$ candidates and 7 anti-$\nu_e$ candidates were observed while 67.5 and 9.0 are expected for $\delta_{CP}=0$ and normal mass ordering. The obtained $2\sigma$ confidence interval for the $CP$ violating phase, $\delta_{CP}$, does not include the $CP$-conserving cases ($\delta_{CP}=0,\pi$). The best-fit values of other parameters are $\sin^2\theta_{23} = 0.526^{+0.032}_{-0.036}$ and $\Delta m^2_{32}=2.463\pm0.065\times10^{-3} \mathrm{eV}^2/c^4$.

PhysicsParticle physics010308 nuclear & particles physicsT2K experimentGeneral Physics and Astronomy01 natural sciencesNeutrino detector0103 physical sciencesCP violationMuon neutrinoNeutrino010306 general physicsNeutrino oscillationElectron neutrinoPhysical Review Letters
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First measurement of the charged current ν¯μ double differential cross section on a water target without pions in the final state

2020

We thank the J-PARC staff for superb accelerator performance. We thank the CERN NA61/SHINE Collaboration for providing valuable particle production data. We acknowledge the support of MEXT, Japan; NSERC (Grant No. SAPPJ-2014-00031), the NRC and CFI, Canada; the CEA and CNRS/IN2P3, France; the DFG, Germany; the INFN, Italy; the National Science Centre and Ministry of Science and Higher Education, Poland; the RSF (Grant No. 19-12-00325) and the Ministry of Science and Higher Education, Russia; MINECO and ERDF funds, Spain; the SNSF and SERI, Switzerland; the STFC, UK; and the DOE, USA. We also thank CERN for the UA1/NOMAD magnet, DESY for the HERA-B magnet mover system, NII for SINET4, the We…

PhysicsScattering cross-section010308 nuclear & particles physics0103 physical sciencesmedia_common.cataloged_instanceLibrary scienceChristian ministryEarly careerEuropean union010306 general physics01 natural sciencesmedia_commonPhysical Review D
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Volume III. DUNE far detector technical coordination

2020

The preponderance of matter over antimatter in the early universe, the dynamics of the supernovae that produced the heavy elements necessary for life, and whether protons eventually decay-these mysteries at the forefront of particle physics and astrophysics are key to understanding the early evolution of our universe, its current state, and its eventual fate. The Deep Underground Neutrino Experiment (DUNE) is an international world-class experiment dedicated to addressing these questions as it searches for leptonic charge-parity symmetry violation, stands ready to capture supernova neutrino bursts, and seeks to observe nucleon decay as a signature of a grand unified theory underlying the st…

Technology530 PhysicsPhysics::Instrumentation and Detectorsmedia_common.quotation_subjectContext (language use)01 natural sciences09 Engineering030218 nuclear medicine & medical imagingneutrino03 medical and health sciences0302 clinical medicine0103 physical sciencesGrand Unified TheoryDeep Underground Neutrino ExperimentHigh Energy PhysicsInstruments & InstrumentationNeutrino oscillations liquid Argon TPC technical design report technical coordinationInstrumentationMathematical Physicsmedia_commonScience & Technology02 Physical Sciences010308 nuclear & particles physicsDetectorVolume (computing)530 PhysikNuclear & Particles PhysicsUniverseSystems engineeringHigh Energy Physics::ExperimentState (computer science)NeutrinoLong baseline neutrino experiment CP violationJournal of Instrumentation
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First measurement of the muon neutrino charged current single pion production cross section on water with the T2K near detector

2017

The T2K off-axis near detector, ND280, is used to make the first differential cross section measurements of muon neutrino charged current single positive pion production on a water target at energies ∼0.8  GeV. The differential measurements are presented as a function of the muon and pion kinematics, in the restricted phase space defined by pπ+>200  MeV/c, pμ>200  MeV/c, cos(θπ+)>0.3 and cos(θμ)>0.3. The total flux integrated νμ charged current single positive pion production cross section on water in the restricted phase space is measured to be ⟨σ⟩ϕ=4.25±0.48(stat)±1.56(syst)×10-40  cm2/nucleon. The total cross section is consistent with the NEUT prediction (5.03×10-40  cm2/nucleon) and 2σ…

Particle physicssingle production [pi]Physics and Astronomy (miscellaneous)Physics::Instrumentation and Detectorswaterneutrinoproduction [pi]FOS: Physical sciencesFluxKAMIOKANDE01 natural sciencesHigh Energy Physics - Experimentcharged currentNuclear physicsHigh Energy Physics - Experiment (hep-ex)phase spacePionnear detectormeasured [differential cross section]secondary beam [neutrino/mu]0103 physical sciences[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]Muon neutrinoddc:530High Energy Physicsmeasured [total cross section]010306 general physicsNuclear Experimentneutrino nucleusCharged currentPhysicsMuon010308 nuclear & particles physicsGenerator (category theory)hep-exJ-PARC Labinteraction [neutrino nucleus]flux [neutrino]Monte Carlo [numerical calculations]3. Good healthkinematicsProduction (computer science)High Energy Physics::ExperimentNucleonParticle Physics - Experimentexperimental results
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Measurement of the single π0 production rate in neutral current neutrino interactions on water

2018

The single π0 production rate in neutral current neutrino interactions on water in a neutrino beam with a peak neutrino energy of 0.6 GeV has been measured using the POD, one of the subdetectors of the T2K near detector. The production rate was measured for data taking periods when the POD contained water (2.64×1020 protons-on-target) and also periods without water (3.49×1020 protons-on-target). A measurement of the neutral current single π0 production rate on water is made using appropriate subtraction of the production rate with water in from the rate with water out of the target region. The subtraction analysis yields 106±41±69 signal events where the uncertainties are statistical (stat.…

PhysicsParticle physicsNeutral currentPhysics::Instrumentation and Detectors010308 nuclear & particles physicsAstrophysics::High Energy Astrophysical PhenomenaDetectorFluxInteraction energy01 natural sciences7. Clean energyNuclear physicsCross section (physics)0103 physical sciencesMass spectrumHigh Energy Physics::ExperimentNeutrinoNuclear Experiment010306 general physicsNucleonPhysical Review D
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SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study

2021

Abstract Background Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling. Methods The primary outcome was the number needed to vaccinate (NNV) to prevent one COVID-19-related death in 1 year. NNVs were based on postoperative SARS-CoV-2 rates and mortality in an international cohort study (surgical patients), and community SARS-CoV-2 incidence and case fatality data (general population). NNV estimates were stratified by age (18–49, 50–69, 70 or more years) and type of surgery. Best- and worst-case scenarios were used to describe uncertainty. Results NNVs were more favourable in su…

MaleCOVID-19 Vaccinesafe surgery; vaccination modelling; COVID-19Vascular damage Radboud Institute for Health Sciences [Radboudumc 16]MULTICENTERComorbidity030230 surgery0302 clinical medicinephase 3 clinical trial (topic)Case fatality rateProspective StudiesSARS-CoV-2 Vaccination Safe surgeryCOVID-19/epidemiologySARS-CoV-2 ; vaccination ; safe surgeryeducation.field_of_studycase fatality rateVaccinationVaccinationAdolescent; Adult; Aged; COVID-19; COVID-19 Vaccines; Comorbidity; Elective Surgical Procedures; Female; Humans; Male; Middle Aged; Postoperative Complications; Preoperative Period; Prospective Studies; SARS-CoV-2; Vaccination; Young Adulthealth care policyElective Surgical Procedures030220 oncology & carcinogenesisvaccination modellingPreoperative PeriodCOVID-19; SARS-CoV-2; cancer; vaccination; outcome; mortality; infection; modellingCohort studyprospective studyHumanmedicine.medical_specialtyArticle03 medical and health sciencesSARS-CoV-2 vaccinationSDG 3 - Good Health and Well-beingCOVID-19 Vaccines/pharmacologyHumansVaccination/methodsElective surgeryeducationAgedScience & TechnologyElective Surgical Procedureadult; aged; Article; cancer grading; cancer surgery; case fatality rate; computer assisted tomography; elective surgery; female; follow up; health care policy; human; incidence; infection rate; infection risk; major clinical study; male; middle aged; mortality; outcome assessment; phase 3 clinical trial (topic); preoperative care; prospective study; sensitivity analysis; seroprevalence; Severe acute respiratory syndrome coronavirus 2; vaccination; young adult; COVID-19; COVID-19 Vaccines; Comorbidity; Elective Surgical Procedures; Postoperative Complications; Preoperative Period; SARS-CoV-2; Vaccination; surgery.Cura preoperatòriamajor clinical studymortalityinfectionProspective StudieincidenceSurgeryHuman medicinePostoperative Complication610 Medizin und GesundheitAcademicSubjects/MED00910Settore MED/18 - CHIRURGIA GENERALESettore MED/29 - CHIRURGIA MAXILLOFACCIALEcomputer assisted tomographyESTUDOS PROSPECTIVOSsurgerysafe surgeryPostoperative Complicationssensitivity analysisSevere acute respiratory syndrome coronavirus 2preoperative careVacunacióProspective cohort studyseroprevalenceIncidence (epidemiology)covidElective Surgical Procedures/methodsMiddle Agedcancer gradingCOVID vaccinationoutcome/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingSARS-CoV-2; vaccination; surgeryOriginal ArticleFemalecancer surgeryAcademicSubjects/MED00010Life Sciences & BiomedicineAdultCOVID-19 VaccinesAdolescentinternational prospective cohort studyPostoperative Complications/prevention & controlPopulationinfection rateSARS-CoV-2/immunologyNOmodellingYoung Adultmedicinefollow upcancerddc:610infection riskoutcome assessmentLS7_4business.industrySARS-CoV-2Number needed to vaccinatePreoperative careCOVID-193126 Surgery anesthesiology intensive care radiologySettore MED/18Reconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10]elective surgeryEmergency medicinebusiness[SDV.MHEP]Life Sciences [q-bio]/Human health and pathologyThe British Journal of Surgery
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Factors associated with first- versus second-generation long-acting antipsychotics prescribed under ordinary clinical practice in Italy

2018

Background For many years, long-acting intramuscular (LAI) antipsychotics have been prescribed predominantly to chronic and severe patients, as a last resort when other treatments failed. Recently, a broader and earlier use of LAIs, particularly second-generation LAIs, has been emphasized. To date, few studies attempted to frame how this change in prescribing took place in real-world practice. Therefore, this study aimed to describe the clinical features of patients prescribed with LAIs, and to explore possible prescribing differences between first- and second-generations LAIs under ordinary clinical practice in Italy. Methods The STAR Network "Depot" Study is an observational, longitudinal…

Genetics and Molecular Biology (all)MalePediatricsEuropean PeopleBipolar DisorderCross-sectional studyEconomicsEpidemiologymedicine.medical_treatmentassessmentviruseslcsh:MedicineSocial SciencesLongitudinal StudieBiochemistryPrescriptionGeographical locations0302 clinical medicineMathematical and Statistical TechniquesBiochemistry Genetics and Molecular Biology (all); Agricultural and Biological Sciences (all)immune system diseasesEpidemiologyMedicine and Health Scienceslong-acting intramuscular (LAI) antipsychotics; clinical practice; assessment; second-generation antipsychotic (SGA) LAIsAntipsychoticsEthnicitiesLongitudinal Studieslcsh:ScienceMultidisciplinaryvirus diseasesDrugsMiddle Agedclinical practiceItalian PeopleEuropePrescriptionsItalyPhysical SciencesAripiprazoleFemaleBivariate AnalysisStatistics (Mathematics)medicine.drugHumanResearch ArticleAntipsychotic AgentsEmploymentAdultmedicine.medical_specialtyAdolescentResearch and Analysis Methods03 medical and health sciencesMental Health and PsychiatrymedicineHumansPaliperidoneBipolar disorderEuropean UnionStatistical MethodsAntipsychoticCross-Sectional StudiePharmacologyRisperidoneBiochemistry Genetics and Molecular Biology (all)business.industryMood Disorderslcsh:Rmedicine.disease030227 psychiatryAntipsychotic AgentCross-Sectional StudiesAgricultural and Biological Sciences (all)Labor EconomicsMultivariate AnalysisSchizophreniaObservational studylcsh:QPopulation Groupingslong-acting intramuscular (LAI) antipsychoticsPeople and placesbusiness030217 neurology & neurosurgerysecond-generation antipsychotic (SGA) LAIsMathematicsPLoS ONE
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Comparing Long-Acting Antipsychotic Discontinuation Rates Under Ordinary Clinical Circumstances: A Survival Analysis from an Observational, Pragmatic…

2021

Background Recent guidelines suggested a wider use of long-acting injectable antipsychotics (LAI) than previously, but naturalistic data on the consequences of LAI use in terms of discontinuation rates and associated factors are still sparse, making it hard for clinicians to be informed on plausible treatment courses. Objective Our objective was to assess, under real-world clinical circumstances, LAI discontinuation rates over a period of 12 months after a first prescription, reasons for discontinuation, and associated factors. Methods The STAR Network ‘Depot Study’ was a naturalistic, multicentre, observational prospective study that enrolled subjects initiating a LAI without restrictions …

MalePediatricsrespectively)0302 clinical medicineDelayed-Action PreparationBrief Psychiatric Rating ScalePharmacology (medical)he STAR Network ‘Depot Study’ prospectively followed 394 subjects initiating treatment with long-acting injections (LAIs) of antipsychotics under naturalistic conditions for 12 months. LAI discontinuation was frequent in everyday clinical practice in ItalyOriginal Research ArticleProspective StudiesProspective cohort studytreatmentMental DisordersHazard ratiowhereas more than half of participants initiating risperidone LAI and olanzapine LAI discontinued during the 12 months of follow-up (51.4 and 62.5%Psychiatric Status Rating ScaleMiddle Agedside efectsPsychiatry and Mental healthItalyMental DisorderFemalehe STAR Network ‘Depot Study’ prospectively followed 394 subjects initiating treatment with long-acting injections (LAIs) of antipsychotics under naturalistic conditions for 12 months. LAI discontinuation was frequent in everyday clinical practice in Italy occurring in almost 40% of the entire sample; side efects participant refusal to continue LAIs and LAIs no longer being required were the most frequently reported reasons for discontinuation. Paliperidone LAI and aripiprazole LAI were the least discontinued medications (33.9 and 35.4% respectively) whereas more than half of participants initiating risperidone LAI and olanzapine LAI discontinued during the 12 months of follow-up (51.4 and 62.5% respectively). In multivariate analysis being prescribed olanzapine LAI and poor medication adherence at baseline were signifcantly associated with higher discontinuation risk.HumanAntipsychotic Agentsmedicine.drugPsychopathologyAdultmedicine.medical_specialtyDiscontinuationFollow-Up StudieMedication Adherence03 medical and health sciencesmedicineHumansPaliperidoneAdverse effectSettore MED/25 - Psichiatriadiscontinuation ratesPsychiatric Status Rating Scalesrespectively). In multivariate analysisbusiness.industryLong-Acting Antipsychoticlong-acting injectable antipsychoticsSurvival AnalysisConfidence intervalparticipant refusal to continue LAIs and LAIs no longer being required were the most frequently reported reasons for discontinuation. Paliperidone LAI and aripiprazole LAI were the least discontinued medications (33.9 and 35.4%030227 psychiatryDiscontinuationProspective StudieAntipsychotic Agentoccurring in almost 40% of the entire sampleDelayed-Action PreparationsNeurology (clinical)business030217 neurology & neurosurgerybeing prescribed olanzapine LAI and poor medication adherence at baseline were signifcantly associated with higher discontinuation riskFollow-Up Studies
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Simultaneous measurement of the muon neutrino charged-current cross section on oxygen and carbon without pions in the final state at T2K

2020

Authors: K. Abe,56 N. Akhlaq,45 R. Akutsu,57 A. Ali,32 C. Alt,11 C. Andreopoulos,54,34 L. Anthony,21 M. Antonova,19 S. Aoki,31 A. Ariga,2 T. Arihara,59 Y. Asada,69 Y. Ashida,32 E. T. Atkin,21 Y. Awataguchi,59 S. Ban,32 M. Barbi,46 G. J. Barker,66 G. Barr,42 D. Barrow,42 M. Batkiewicz-Kwasniak,15 A. Beloshapkin,26 F. Bench,34 V. Berardi,22 L. Berns,58 S. Bhadra,70 S. Bienstock,53 S. Bolognesi,6 T. Bonus,68 B. Bourguille,18 S. B. Boyd,66 A. Bravar,13 D. Bravo Berguño,1 C. Bronner,56 S. Bron,13 A. Bubak,51 M. Buizza Avanzini ,10 T. Campbell,7 S. Cao,16 S. L. Cartwright,50 M. G. Catanesi,22 A. Cervera,19 D. Cherdack,17 N. Chikuma,55 G. Christodoulou,12 M. Cicerchia,24,† J. Coleman,34 G. Collazu…

Fermi gasPhysics::Instrumentation and DetectorsMonte Carlo methodmeasured [channel cross section]KAMIOKANDEmuon neutrino01 natural sciencesPhysics Particles & FieldsHigh Energy Physics - ExperimentHigh Energy Physics - Experiment (hep-ex)secondary beam [neutrino/mu][PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]Particle Physics ExperimentsMuon neutrinoQDCharged currentQCPhysicsneutrino: energy spectrumJ-PARC LabPhysicsinteraction [neutrino nucleus]T2K experimentoscillation [neutrino]Monte Carlo [numerical calculations]suppressionNuclear & Particles PhysicskinematicsPhysical Sciences0202 Atomic Molecular Nuclear Particle and Plasma PhysicsGround statenumerical calculations: Monte Carlochannel cross section: measuredParticle Physics - Experiment530 PhysicsFOS: Physical sciencesAstronomy & Astrophysics530Nuclear physicsPionnear detector0103 physical sciencessimultaneous measurement0201 Astronomical and Space SciencesSCATTERINGddc:530010306 general physicsNeutrino oscillation0206 Quantum Physicscross section: charged currentMuonScience & Technologynucleus: ground stateNUCLEI010308 nuclear & particles physicsnucleus: targethep-excarbonenergy spectrum [neutrino]neutrino nucleus: interactionground state [nucleus]neutrino/mu: secondary beamtarget [nucleus]random phase approximationcharged current [cross section]High Energy Physics::Experimentneutrino: oscillationoxygenexperimental resultsPhysical Review D
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LBNO-DEMO: Large-scale neutrino detector demonstrators for phased performance assessment in view of a long-baseline oscillation experiment

2014

In June 2012, an Expression of Interest for a long-baseline experiment (LBNO) has been submitted to the CERN SPSC. LBNO considers three types of neutrino detector technologies: a double-phase liquid argon (LAr) TPC and a magnetised iron detector as far detectors. For the near detector, a high-pressure gas TPC embedded in a calorimeter and a magnet is the baseline design. A mandatory milestone is a concrete prototyping effort towards the envisioned large-scale detectors, and an accompanying campaign of measurements aimed at assessing the detector associated systematic errors. The proposed $6\times 6\times 6$m$^3$ DLAr is an industrial prototype of the design discussed in the EoI and scalable…

High Energy Physics - Experiment (hep-ex)Physics - Instrumentation and DetectorsPhysics::Instrumentation and Detectors[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]FOS: Physical sciencesHigh Energy Physics::ExperimentInstrumentation and Detectors (physics.ins-det)[PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det]High Energy Physics - Experiment
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Prevalence and correlates of QTc prolongation in Italian psychiatric care: cross-sectional multicentre study.

2016

Aims.In recent years several warnings have been issued by regulatory authorities on the risk of electrocardiogram abnormalities in individuals exposed to psychotropic drugs. As a consequence of these warnings, monitoring of the QT interval corrected for heart rate (QTc) has become increasingly common. This study was conducted to measure the frequency of QTc prolongation in unselected psychiatric patients, and to document the associated factors using a cross-sectional approach.Method.The study was carried out in 35 Italian psychiatric services that are part of the STAR (Servizi Territoriali Associati per la Ricerca) Network, a research group established to produce scientific knowledge by col…

AdultMalemedicine.medical_specialtyPsychotropic drugsEpidemiologymedicine.medical_treatmentLong QT syndromeAntidepressantDrug overdoseAdverse effectQT intervalAntipsychotic03 medical and health sciencesElectrocardiography0302 clinical medicineRisk FactorsPsychotropic drugmedicinePrevalenceHumanscardiovascular diseasesAntipsychoticAdverse effectPsychiatrySettore MED/25 - PsichiatriaPolypharmacybusiness.industryEnvironmental and Occupational HealthPublic Health Environmental and Occupational HealthAdverse effect; Antidepressant; Antipsychotic; Psychotropic drugs; Epidemiology; Public Health; Environmental and Occupational Health; Psychiatry and Mental HealthOriginal Articlesmedicine.diseaseAdverse effect; Antidepressant; Antipsychotic; Psychotropic drugs; Epidemiology; Public Health Environmental and Occupational Health; Psychiatry and Mental Health030227 psychiatrySubstance abuseLong QT SyndromeCross-Sectional StudiesItalyPsychiatry and Mental HealthPolypharmacyAripiprazoleFemalePublic HealthbusinessAntidepressant; adverse effect; antipsychotic; psychotropic drugsAdverse effect; Antidepressant; Antipsychotic; Psychotropic drugs; Adult; Antipsychotic Agents; Cross-Sectional Studies; Electrocardiography; Female; Humans; Italy; Long QT Syndrome; Male; Prevalence; Risk Factors; Polypharmacy; Epidemiology; Public Health Environmental and Occupational Health; Psychiatry and Mental Health030217 neurology & neurosurgerymedicine.drugAntipsychotic AgentsEpidemiology and psychiatric sciences
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