0000000000578526

AUTHOR

J. Henry

showing 2 related works from this author

SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study

2021

Abstract Background Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling. Methods The primary outcome was the number needed to vaccinate (NNV) to prevent one COVID-19-related death in 1 year. NNVs were based on postoperative SARS-CoV-2 rates and mortality in an international cohort study (surgical patients), and community SARS-CoV-2 incidence and case fatality data (general population). NNV estimates were stratified by age (18–49, 50–69, 70 or more years) and type of surgery. Best- and worst-case scenarios were used to describe uncertainty. Results NNVs were more favourable in su…

MaleCOVID-19 Vaccinesafe surgery; vaccination modelling; COVID-19Vascular damage Radboud Institute for Health Sciences [Radboudumc 16]MULTICENTERComorbidity030230 surgery0302 clinical medicinephase 3 clinical trial (topic)Case fatality rateProspective StudiesSARS-CoV-2 Vaccination Safe surgeryCOVID-19/epidemiologySARS-CoV-2 ; vaccination ; safe surgeryeducation.field_of_studycase fatality rateVaccinationVaccinationAdolescent; Adult; Aged; COVID-19; COVID-19 Vaccines; Comorbidity; Elective Surgical Procedures; Female; Humans; Male; Middle Aged; Postoperative Complications; Preoperative Period; Prospective Studies; SARS-CoV-2; Vaccination; Young Adulthealth care policyElective Surgical Procedures030220 oncology & carcinogenesisvaccination modellingPreoperative PeriodCOVID-19; SARS-CoV-2; cancer; vaccination; outcome; mortality; infection; modellingCohort studyprospective studyHumanmedicine.medical_specialtyArticle03 medical and health sciencesSARS-CoV-2 vaccinationSDG 3 - Good Health and Well-beingCOVID-19 Vaccines/pharmacologyHumansVaccination/methodsElective surgeryeducationAgedScience & TechnologyElective Surgical Procedureadult; aged; Article; cancer grading; cancer surgery; case fatality rate; computer assisted tomography; elective surgery; female; follow up; health care policy; human; incidence; infection rate; infection risk; major clinical study; male; middle aged; mortality; outcome assessment; phase 3 clinical trial (topic); preoperative care; prospective study; sensitivity analysis; seroprevalence; Severe acute respiratory syndrome coronavirus 2; vaccination; young adult; COVID-19; COVID-19 Vaccines; Comorbidity; Elective Surgical Procedures; Postoperative Complications; Preoperative Period; SARS-CoV-2; Vaccination; surgery.Cura preoperatòriamajor clinical studymortalityinfectionProspective StudieincidenceSurgeryHuman medicinePostoperative Complication610 Medizin und GesundheitAcademicSubjects/MED00910Settore MED/18 - CHIRURGIA GENERALESettore MED/29 - CHIRURGIA MAXILLOFACCIALEcomputer assisted tomographyESTUDOS PROSPECTIVOSsurgerysafe surgeryPostoperative Complicationssensitivity analysisSevere acute respiratory syndrome coronavirus 2preoperative careVacunacióProspective cohort studyseroprevalenceIncidence (epidemiology)covidElective Surgical Procedures/methodsMiddle Agedcancer gradingCOVID vaccinationoutcome/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingSARS-CoV-2; vaccination; surgeryOriginal ArticleFemalecancer surgeryAcademicSubjects/MED00010Life Sciences & BiomedicineAdultCOVID-19 VaccinesAdolescentinternational prospective cohort studyPostoperative Complications/prevention & controlPopulationinfection rateSARS-CoV-2/immunologyNOmodellingYoung Adultmedicinefollow upcancerddc:610infection riskoutcome assessmentLS7_4business.industrySARS-CoV-2Number needed to vaccinatePreoperative careCOVID-193126 Surgery anesthesiology intensive care radiologySettore MED/18Reconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10]elective surgeryEmergency medicinebusiness[SDV.MHEP]Life Sciences [q-bio]/Human health and pathologyThe British Journal of Surgery
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The Large Hadron–Electron Collider at the HL-LHC

2021

The Large Hadron-Electron Collider (LHeC) is designed to move the field of deep inelastic scattering (DIS) to the energy and intensity frontier of particle physics. Exploiting energy-recovery technology, it collides a novel, intense electron beam with a proton or ion beam from the High-Luminosity Large Hadron Collider (HL-LHC). The accelerator and interaction region are designed for concurrent electron-proton and proton-proton operations. This report represents an update to the LHeC's conceptual design report (CDR), published in 2012. It comprises new results on the parton structure of the proton and heavier nuclei, QCD dynamics, and electroweak and top-quark physics. It is shown how the LH…

energy recoverylepton nucleus: scatteringparton: distribution functionhiukkasfysiikka7. Clean energy01 natural sciencesaccelerator physicsHigh Energy Physics - Phenomenology (hep-ph)HEAVY FLAVOR CONTRIBUTIONSenergy-recovery- linacNuclear Experimentcolliding beams [electron p]deep-inelastic scatteringtop and electroweak physicsnew physicsPhysicsSTRUCTURE-FUNCTION RATIOSMonte Carlo [numerical calculations]buildingsprimary [vertex]High Energy Physics - Phenomenologyelectron p: colliding beamskinematicsNuclear Physics - Theoryfinal state: hadronicp: distribution functionbeyond Standard Modelvertex: primarynumerical calculations: Monte Carlodistribution function [parton]High-lumiLHCSTRUCTURE-FUNCTION F-2(X[PHYS.NUCL]Physics [physics]/Nuclear Theory [nucl-th]ion: beam[PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex]114 Physical sciencesNuclear Theory (nucl-th)deep inelastic scatteringquantum chromodynamicsddc:530010306 general physicsdeep-inelastic scattering; high-lumi LHC; QCD; Higgs; top and electroweak physics; nuclear physics; beyond standard Model; energy-recovery- linac; accelerator physics010308 nuclear & particles physicshigh-lumi LHCresolutionscattering [electron p]structure function [nucleus]sensitivitybeam [electron]energy-recovery-linacHiggsacceptanceNuclear TheoryHIGH-ENERGY FACTORIZATIONdistribution function [p]density [parton]Higgs; High-lumi LHCHigh Energy Physics - Experimentdesign [detector]High Energy Physics - Experiment (hep-ex)electron: linear acceleratorelectron hadron: scatteringCERN LHC Coll: upgrade[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]scattering [electron hadron]FCCelectron: beamNuclear Experiment (nucl-ex)linear accelerator [electron]Nuclear ExperimentlatticesuperconductivityEnergy-recoverylinacBeyond Standard ModeNuclear physics; QCDelectron nucleus: colliding beamsparton: densitycolliding beams [electron nucleus]Particle Physics - ExperimentNUCLEON STRUCTURE FUNCTIONSNuclear and High Energy Physicsscattering [lepton nucleus]beam [ion]FOS: Physical sciencesnucleus: structure functionhadronic [final state]electron p: scatteringTRANSVERSE-MOMENTUM DEPENDENCEnuclear physics0103 physical sciencesNuclear Physics - Experimentstructureupgrade [CERN LHC Coll]detector: designParticle Physics - PhenomenologyDEEP-INELASTIC-SCATTERINGelectroweak interaction3-LOOP SPLITTING FUNCTIONSCLASSICAL RADIATION ZEROScalibrationAccelerators and Storage RingsQCDmagnethigh [current]13. Climate action[PHYS.HPHE]Physics [physics]/High Energy Physics - Phenomenology [hep-ph]LHeCPhysics::Accelerator PhysicsJET CROSS-SECTIONSHigh Energy Physics::Experimentcurrent: highJournal of Physics G: Nuclear and Particle Physics
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