0000000000584151
AUTHOR
N. Veronese
showing 29 related works from this author
Nutrition and physical activity in the prevention and treatment of sarcopenia: systematic review
2017
Summary This systematic review summarizes the effect of\ud combined exercise and nutrition intervention on muscle mass\ud and muscle function. A total of 37 RCTs were identified.\ud Results indicate that physical exercise has a positive impact\ud on muscle mass and muscle function in subjects aged 65 years\ud and older. However, any interactive effect of dietary supplementation\ud appears to be limited.\ud Introduction In 2013, Denison et al. conducted a systematic\ud review including 17 randomized controlled trials\ud (RCTs) to explore the effect of combined exercise and\ud nutrition intervention to improve muscle mass, muscle\ud strength, or physical performance in older people.\ud They c…
Higher animal-derived dietary protein intake is associated with lower prevalence of frailty
2019
Background: It is accepted that malnutrition is involved in the pathophysiology of frailty. However, the relationship between dietary animal-derived protein (DAP) intake and the prevalence of frailty is still unclear. Using data from the FRAIL Project, we aimed to determine whether DAP consumption is associated with frailty in community-dwellers aged 65 years and older. Methods: In this cross-sectional study involving only participants older than 65 years, DAP intake was evaluated through specific items of the Mini-Nutritional Assessment (MNA). Frailty status was assessed according to the Cardiovascular Health Study (CHS) model, which consists of five items (unintentional weight loss, weakn…
Sarcopenic osteoarthritis: a new entity in geriatric medicine?
2018
Purpose: Osteoarthritis, a disease characterized by cartilage degradation, abnormal subchondral bone remodeling and some grade of inflammation, and sarcopenia, a condition of low muscle mass associated with reduced strength and function, are prevalent disorders in older adults. In this review, we examine what is known about the relationship between osteoarthritis and sarcopenia, with particular focus on the older population. We also discuss how osteoarthritis and sarcopenia may interact and affect each other in clinical progression and the potential benefits from developing treatments that address such muscular-skeletal interaction. Methods: We searched in Pubmed and Scopus through a combin…
Evaluation of bio-psycho-social frailty in older persons on the territory: The method and the experience of the ‘medesano health house’
2020
Background and aim of the work: Frailty in older people is a situation of risk of dependency caused by many factors. On this consideration, the Medesano city started a survey on the condition of fragility of people >75 aimed at building a monitoring system for timely interventions on the factors of risk and implementation of measures for preventing dependency. Methods: The survey was conducted jointly by the family doctor and the social worker in the City. The multidimensional assessment considered logistic and housing conditions, disease, medications, basic and instumental acitvities of daily living, neurological and psycological conditions. Results: The survey included 761 older people…
Vitamin D status in anorexia nervosa: A meta-analysis
2015
Objective In anorexia nervosa (AN), osteoporosis and osteopenia are common, which have been associated with low circulating levels of vitamin D (VitD) in other settings. We aimed to meta-analyze cross-sectional studies reporting on VitD parameters in patients with AN and healthy controls (HCs). Method Electronic PubMed search from database inception until December 31, 2013 and meta-analysis of cross-sectional studies comparing serum levels of 25-hydroxyvitamin D (25OH-D), 1,25-dihydroxyvitamin D (1,25OH-D) and dietary VitD between patients with AN and HCs, before or after VitD supplementation. We calculated random effects standardized mean differences (SMDs) ±95% confidence intervals (CIs) …
Integrated Small Dense Low-density Lipoprotein Profile in Cardiovascular Disease and Cancer: A longitudinal study
2019
Background/Aim: Low-density lipoproteins (LDL) are a heterogeneous class of particles that differ in size and density from each other. Small dense LDL (sdLDL) particles are considered more atherogenic than larger particles. The aim of the study was to evaluate serum levels of sdLDL in patients who died from cardiovascular diseases (CVD) or cancer in a cohort of patients followed up in the De Bellis Research Hospital for 20 years. Patients and Methods: A total of 75 participants who died of cancer and 87 who died of CVD were enrolled and they were matched for age and sex with 135 healthy controls, i.e. without CVD or cancer and are still alive. Results: Patients who died from cancer had the …
The frail patient with heart disease: An emerging and challenging issue
2018
Frailty and cardiovascular disease (CVD) are two common conditions that may affect clinical outcomes in older people. Epidemiological studies suggest that CVD is one of the most important contributor to the development of frailty in the aged patient, and the latter can therefore be considered a potential CVD risk factor. Moreover, traditional CVD risk factors are also known to be important for developing frailty. This close relationship between CVD and frailty is due, in part, to the shared etiological factors, which include low-grade inflammation, cellular senescence, and endocrine dysregulation. Therefore, the early detection of frailty is important in the management of patients with CVD …
Orthostatic hypotension and health outcomes: an umbrella review of observational studies
2019
To investigate potential relationships between orthostatic hypotension (OH) and negative health outcomes and mortality, through an umbrella review with integrated meta-analyses. Orthostatic hypotension is significantly associated with several negative outcomes in older people, but a suggestive evidence is available only for higher risk of coronary heart disease congestive heart failure, stroke, falls dementia, and all-cause mortality. Orthostatic hypotension seems to be significantly associated with several negative health outcomes in older people, even if only associations with coronary heart disease, congestive heart failure, stroke, falls, dementia, and all-cause mortality are supported …
Association between sarcopenia and diabetes: a systematic review and meta-analysis of observational studies
2019
To summarize the prevalence of diabetes in people with sarcopenia (and vice versa) through a meta-analytic approach of available observational studies. In this work, we have presented the findings of the first full methodological systematic review and meta-analysis of observational studies exploring the relationship between diabetes and sarcopenia. Our findings overall emphasize the reciprocal relationship between diabetes and sarcopenia in terms of risk of occurrence, that is sarcopenia increases the risk of diabetes being present and vice versa. This study provides support for further research into the prognosis of people with both diabetes and sarcopenia and the value of interventional s…
Dietary inflammatory index and mortality: a cohort longitudinal study in a Mediterranean area
2020
Background: Higher Dietary Inflammatory Index (DII®) scores are associated with increased morbidity and mortality. However, little is known about the effects of DII on mortality in Mediterranean countries. Therefore, in the present study, we aimed to investigate the potential association between DII scores and overall, cancer and cardiovascular disease (CVD) mortality in people living in a Mediterranean area. Methods: DII scores were calculated using a validated food-frequency questionnaire. DII scores were then categorised into tertiles. Mortality was ascertained via death certificates. The association between DII scores with overall and cause-specific mortality was assessed via a multivar…
Trends in adherence to the Mediterranean diet in South Italy: A cross sectional study
2019
Background and aims: Increasing literature data show that adherence to the Mediterranean diet is undergoing profound changes in recent years, albeit with marked differences across nations. In Italy, one of the cradles of the Mediterranean diet, the literature regarding the trend for Mediterranean diet adherence is conflicting. Thus, we aimed to explore the trends of adherence to the Mediterranean diet in a large cohort of participants living in South Italy, over 20 years from 1985–86 to 2005–06. Methods and results: Cross-sectional study with two evaluations, one made in 1985–86 and another in 2005–06; all participants were adults aged 30–70 years of age. The adherence to the Mediterranean …
Coffee Intake and Liver Steatosis: A Population Study in a Mediterranean Area
2018
Coffee drinking seems to have several beneficial effects on health outcomes. However, the effect on hepatic steatosis, depending on a high alcohol consumption (AFLD, alcoholic fatty liver disease) or on metabolic factors (non-alcoholic fatty liver disease, NAFLD), is still equivocal. Thus, we aimed to explore the potential association between coffee consumption and the presence and severity of hepatic steatosis in people with NAFLD or AFLD. In this cross-sectional study, coffee drinking was recorded using a semi-quantitative food frequency questionnaire, and categorized as yes vs. no and as 0, 1, 2, ≥3. The degree of fatty liver was assessed through a standardized ultrasound examination (sc…
Erratum to: Self-reported flares are predictors of radiographic progression in rheumatoid arthritis patients in 28-joint disease activity score remis…
2016
Unfortunately, after publication of this article [1], it was noticed that the author name Constantino Botsios was incorrectly spelled during the production process. The corrected name can be seen in the author list above and the original article has also been updated to reflect this. © 2016 Ometto et al.
Attributes and definitions of locomotor capacity in older people: a World Health Organisation (WHO) locomotor capacity working group meeting report
2022
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Nutrition and lipidomic profile in colorectal cancers
2018
Background: Adherence to a healthy diet has been reported to be essential for the primary prevention of colorectal cancer, through a reduction of tissue inflammation, a low concentration of circulating lipoproteins and lower levels of serum cholesterol. Since an altered expression of the fatty acids pattern has been demonstrated to be a crucial event in colorectal carcinogenesis, lipidomic analysis is considered able to identify early diagnostic and prognostic biomarkers of complex diseases such as colorectal cancer. Methods: cell membrane fatty acid profile and serum lipoproteins pattern were evaluated by gas chromatography and electrophoresis method respectively. Results: There is a close…
Association of Osteoarthritis with Increased Risk of Cardiovascular Diseases in the Elderly: Findings from the Progetto Veneto Anziano Study Cohort
2015
Objective The possible relevance of osteoarthritis (OA) as a cardiovascular disease (CVD) risk factor is still debated. The aim of this study was to investigate the association between OA and the onset of CVD in older individuals. Methods Among a sample of 3,099 elderly subjects, 2,158 were identified as having no CVD at baseline and were followed up for a mean ± SD 4.4 ± 1.2 years. OA was defined using a standardized algorithm that investigated disease history, medical documentation (including radiographic reports), symptoms, and physical examination of the joints. Incident CVD was defined as the onset of coronary artery disease, heart failure, stroke/transient ischemic attack, peripheral …
Association between urinary incontinence and frailty: a systematic review and meta-analysis
2018
Purpose: Urinary incontinence (UI) and frailty are common geriatric syndromes. Although literature increasingly supports a relationship between these two conditions, no systematic review and meta-analysis has been performed on this topic. Therefore, we aimed to investigate the potential association between UI and frailty, through a meta-analytic approach. Methods: A systematic search in major databases was undertaken until 15th March 2018 for studies reporting the association between UI and frailty. The prevalence of UI in people with frailty (vs. those without) was pooled through an odds ratio (OR) and 95% confidence intervals (CIs), with a random-effects model. The other outcomes were sum…
Physical activity and exercise in mild cognitive impairment and dementia::an umbrella review of intervention and observational studies
2020
Objectives:\ud \ud The aim of this umbrella review was to determine the effect of physical activity/exercise on improving cognitive and noncognitive outcomes in people with MCI (mild cognitive impairment) and dementia.\ud \ud Design:\ud \ud Umbrella review of systematic reviews (SR), with or without meta-analyses (MAs), of randomized controlled trials (RCTs) and observational studies.\ud \ud Settings and Participants:\ud \ud People with MCI or dementia, confirmed through validated assessment measures. Any form of physical activity/exercise was included. As controls, we included participants not following any prespecified physical activity/exercise intervention or following the same standard…
Leisure-Time Sedentary Behavior and Obesity Among 116,762 Adolescents Aged 12-15 Years from 41 Low- and Middle-Income Countries
2019
Objective: Rates of adolescent obesity are increasing worldwide, with steeper increases being observed in low- and middle-income countries (LMICs). Sedentary behavior (SB) has been associated with various physical and mental health conditions. Little is known about the association between SB and obesity among adolescents in LMICs. This cross-sectional study explored the associations between SB and obesity in adolescents from 41 LMICs. Methods: Obesity was measured using BMI; SB was assessed through self-report and was considered for all times except when subjects were at school or doing homework. Results: Data from the Global School-based Student Health Survey were analyzed in 116,762 adole…
Reducing NAFLD-screening time: A comparative study of eight diagnostic methods offering an alternative to ultrasound scans.
2018
Background & Aims: The use of ultrasound scan (US) in non-alcoholic fatty liver disease (NAFLD) screening overloads US waiting lists. We hypothesized and tested a hybrid two-step method, consisting of applying a formula, to exclude subjects at low risk, before US. Methods: The sample included 2970 males and females (937 with NAFLD) diagnosed by US. We selected eight formulas: Fatty Liver Index (FLI), Hepatic Steatosis Index (HIS), body mass index (BMI), waist circumference (WC), Abdominal Volume Index (AVI), waist-to-height ratio (WHtR), waist/height0.5 (WHT.5R) and Body Roundness Index (BRI), and calculated their performance in the two-step method evaluating percentage reduction of the…
A rare case of sepsis due to Corynebacterium macginleyi from central venous catheter in an elderly woman
2011
Corynebacterium macginleyi is a gram positive rod that causes especially ocular infections: since now only six elderly cases of extraocular infection are described. A 76 years old bedridden woman with a central venous catheter was hospitalized for 10 days of persistent fever. She was treated before with vancomicin and then with imipenem. The clinical conditions improved and the patient was discharged after two weeks of hospitalization. Among recognised risk factors for this infection the advanced age, indwelling devices and immunosuppression seem the most important. On the other hand, the antibiotics of choice are glycopeptides while the association of another antibiotic is recommended in o…
The multidimensional prognostic index (MPI) for the prognostic stratification of older inpatients with COVID-19: A multicenter prospective observatio…
2021
Background: The topic of prognosis in COVID-19 research may be important in adopting appropriate clinical decisions. Multidimensional prognostic index (MPI) is a frailty assessment tool widely used for stratifying prognosis in older people, but data regarding inpatients, affected by COVID-19, are not available. Objectives: To evaluate whether MPI can predict in-hospital mortality and the admission to intensive care unit (ICU) in older inpatients hospitalized for COVID-19 infection. Methods: In this longitudinal, Italian, multi-center study, older patients with COVID-19 were included. MPI was calculated using eight different domains typical of comprehensive geriatric assessment and categoriz…
Associations between cardiac arrhythmia, incident disability in activities of daily living and physical performance: The ilsa study
2020
Background Cardiac arrhythmias are common conditions in older people. Unfortunately, there is limited literature on associations between cardiac arrhythmias and physical performance or disability. We therefore aimed to prospectively investigate associations between cardiac arrhythmias and changes in disability and physical performance during 8 years of follow-up, using data from the Italian Longitudinal Study on Aging (ILSA). Methods Cardiac arrhythmias diagnosis was posed through a screening phase, confirmed by a physician. The onset of disability in activities of daily living (ADL) and the changes in several physical performance tests during follow-up were considered as outcomes. Fully-ad…
<p>Agreement of a Short Form of the Self-Administered Multidimensional Prognostic Index (SELFY-MPI-SF): A Useful Tool for the Self-Assessment o…
2020
Alberto Cella,1 Alberto Ferrari,2 Giuseppe Rengo,3 Vincenzo Solfrizzi,4 Nicola Veronese,5 Matteo Puntoni,6 Sabrina Zora,1 Alberto Pilotto,1,4 Filippo Fimognari7 On behalf of the SELFY-MPI SIGOT Investigators1Geriatric Unit, Department of Geriatric Care, Orthogeriatrics and Rehabilitation, EO Galliera Hospital, Genova, Italy; 2Geriatric Unit, Arcispedale S. Maria Nuova, AUSL Reggio Emilia, Reggio Emilia, Italy; 3Department of Translational Medical Sciences, Division of Geriatrics, Federico II University, Napoli, Italy; 4Department of Interdisciplinary Medicine, University of Bari, Bari, Italy; 5Primary Care Department, Azienda ULSS 3 Serenissima, Venice, Italy; 6Scientific Coordination Unit,…
Association of Antidementia Drugs and Mortality in Community-Dwelling Frail Older Patients With Dementia: The Role of Mortality Risk Assessment
2018
Objective: To evaluate whether treatment with antidementia drugs is associated with reduced mortality in older patients with different mortality risk at baseline. Design: Retrospective. Setting: Community-dwelling. Participants: A total of 6818 older people who underwent a Standardized Multidimensional Assessment Schedule for Adults and Aged Persons (SVaMA) evaluation to determine accessibility to homecare services or nursing home admission from 2005 to 2013 in the Padova Health District, Italy were included. Measurements: Mortality risk at baseline was calculated by the Multidimensional Prognostic Index (MPI), based on information collected with the SVaMA. Participants were categorized to …
Corrigendum to “Inflammation and frailty in the elderly: A systematic review and meta-analysis” (Ageing Research Reviews (2016) 31 (1–18) (S156816371…
2017
Since the publication of our meta-analysis it has come to light that we inadvertently categorised one study (Gale et al. 2013) as a cross sectional study instead of its true design as a longitudinal study. We have recalculated the analyses affected which is isolated to the cross sectional longitudinal biomarkers of C reactive protein. The updated analyses have not significantly changed our findings regarding CRP or the narrative of the paper in any perceptible way. Specifically, the new OR for CRP longitudinal studies is now 1.08 (95%CI 0.87–1.34) compared to a previous value of 1.06 (95%CI: 0.78–1.44) (please see the new Fig. 1a). Similarly, after removing the study of Gale et al., the cro…
Gender differences in coronary heart disease in elderly population
2017
Coronary heart diseases (CHDs) represent one of the leading causes of death in developed countries, and particularly in elderly populations. There are several genderspecific differences in the risk factors, presentation, management, and prognosis of CHDs in middle-aged and elderly adults. Elderly women, for example, tend to present with these diseases at an older age compared to men and are characterized by a greater number of risk factors and comorbidities at diagnosis. As far as symptomatic acute coronary syndromes are concerned, older women are less likely to report critical arterial obstruction, but seem to be more frequently affected by adverse outcomes and higher mortality. These feat…
Development of a European consensus from dentists, dental hygienists and physicians on a standard for oral health care in care-dependent older people…
2020
ObjectivesThis study aimed to obtain a consensus on oral health policy, access to dental care, oral hygiene measures and training levels.BackgroundPoor oral health is widespread in care-dependent older people, but no consensus for a minimum standard of oral health care exists yet.MethodsThe e-Delphi approach was applied to a selected panel of interdisciplinary experts. Data analysis was based on three measurements: (a) ≥70% of experts’ opinion fall into category “agree or strongly agree,” (b) median score on the 5-point Likert scale ≥4, (c) interquartile range ≤1.ResultsA total of 31 experts from 17 European countries participated in this survey. Agreement was achieved for a compulsory dent…
Supplementary Material for: Perceived Stress and Mild Cognitive Impairment among 32,715 Community-Dwelling Older Adults across Six Low- and Middle-In…
2018
Background: Perceived stress may be a modifiable risk factor for mild cognitive impairment (MCI) and ultimately dementia, but studies on this topic from low- and middle-income countries (LMICs) are lacking. Objective: We assessed the association between perceived stress and MCI in six LMICs (China, Ghana, India, Mexico, Russia, and South Africa) using nationally representative data. Methods: Cross-sectional, community-based data on individuals aged ≥50 years from the World Health Organization’s Study on Global Ageing and Adult Health were analyzed. The definition of MCI was based on the National Institute on Ageing-Alzheimer’s Association criteria. A perceived stress score (range 0 [lowest …